Drug Toxicology Phencyclidine, with Confirmation, Oral Fluid
*Build Your Own Panel Eligible [?]
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$371
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Description:
Oral fluid is composed of saliva, mixed with buccal and mucosal transudates, cellular debris, bacteria, and residue of ingested products. Oral fluid as a test matrix shows promise for detection of recent drug use, and a significant body of scientific literature documents drug disposition and detection times. Researchers comparing effectiveness of oral fluid and urine drug testing found a similar pattern and frequency of positive drug test results in the general workforce over the same general period. Similarly in pain clinics, the pattern of licit and illicit drugs and metabolites observed in oral fluid paralleled results reported for urine, with some minor differences in detection rates for different drug classes. In some cases, oral fluid testing may be an acceptable alternative or the only available matrix. As an ultra-filtrate of blood, however, it shares the limitations of a decreased window of detection versus conventional urine drug testing.
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Price:
$371
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Drug Toxicology Phentermine, with Confirmation, Oral Fluid
*Build Your Own Panel Eligible [?]
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$371
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Description:
Phentermine is a prescription stimulant. Because taking phentermine comes with a risk of dependence, it is considered a controlled substance. It's chemically similar to the stimulant amphetamine, which is also a controlled substance. The test is a definitive assay using Liquid Chromatography Mass Spectroscopy methodology. Therapeutic urine drug monitoring of phentermine is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.
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Price:
$371
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Drug Toxicology Pregabalin, with Confirmation, Oral Fluid
*Build Your Own Panel Eligible [?]
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$371
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Description:
Pregabalin is used as an adjunct therapy for partial seizures, for the treatment of generalized anxiety disorder, neuropathic pain and fibromyalgia. Oral fluid is composed of saliva, mixed with buccal and mucosal transudates, cellular debris, bacteria, and residue of ingested products. Oral fluid as a test matrix shows promise for detection of recent drug use, and a significant body of scientific literature documents drug disposition and detection times. Researchers comparing effectiveness of oral fluid and urine drug testing found a similar pattern and frequency of positive drug test results in the general workforce over the same general period. Similarly in pain clinics, the pattern of licit and illicit drugs and metabolites observed in oral fluid paralleled results reported for urine, with some minor differences in detection rates for different drug classes. In some cases, oral fluid testing may be an acceptable alternative or the only available matrix. As an ultra-filtrate of blood, however, it shares the limitations of a decreased window of detection versus conventional urine drug testing.
Categories:
Price:
$371
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Drug Toxicology Zolpidem, with Confirmation, Oral Fluid
*Build Your Own Panel Eligible [?]
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$371
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Description:
Oral fluid is composed of saliva, mixed with buccal and mucosal transudates, cellular debris, bacteria, and residue of ingested products. Oral fluid as a test matrix shows promise for detection of recent drug use, and a significant body of scientific literature documents drug disposition and detection times. Researchers comparing effectiveness of oral fluid and urine drug testing found a similar pattern and frequency of positive drug test results in the general workforce over the same general period. Similarly in pain clinics, the pattern of licit and illicit drugs and metabolites observed in oral fluid paralleled results reported for urine, with some minor differences in detection rates for different drug classes. In some cases, oral fluid testing may be an acceptable alternative or the only available matrix. As an ultra-filtrate of blood, however, it shares the limitations of a decreased window of detection versus conventional urine drug testing.
Categories:
Price:
$371
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dRVVT Screen with Reflex to dRVVT Confirm and dRVVT 1:1 Mix
*Build Your Own Panel Eligible [?]
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$114
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Description:
The dilute Russell Viper Venom time integrated test is a sensitive method for the detection of Lupus Anticoagulants (LA). LA are autoantibodies that target protein-phospholipid complexes and are found in a variety of clinical conditions. In some patients, a confirmed positive result is associated with an increased thrombotic risk, and is often found in women who have recurrent fetal loss. As Lupus anticoagulants reflect a heterogenous group of antibodies, international consensus guidelines on testing require at least two screening assays be used for a complete evaluation. Refer to Lupus Anticoagulant Comprehensive Evaluation which includes the DRVVT plus a second pathway of testing, the PTT-LA with reflex to Hexagonal Phase Confirm and Thrombin Time. Note: Target specific anticoagulant therapy (anti-XA, anti-thrombin) may cause false positive results.
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Price:
$114
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Duck Feathers (e86) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This allergen-specific IgE antibody test quantifies an individual’s IgE response to duck feathers. It is an in vitro quantitative assay that is intended to be used in conjunction with other clinical information to aid in the diagnosis of allergic diseases [1]. While allergen-specific serum IgE testing is considered comparable to skin testing in many instances, both the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology recognize that allergen-specific serum IgE testing may be preferred in some clinical situations. These include 1) the presence of widespread skin disease, 2) the recent use of antihistamines or other medications that can affect the results of allergy skin tests, 3) uncooperative patients, and 4) medical history suggesting that allergen skin testing would pose a significant risk for a serious allergic reaction [1]. A definitive clinical diagnosis of allergy should not be based on the results of any single diagnostic method, but should be made by a trained healthcare provider after all clinical and laboratory findings have been evaluated. More specific information about this allergen can be found at http://www.phadia.com/en/Products/Allergy-testing-products/ImmunoCAP-Allergen-Information/Epidermals-and-Animal-Proteins/Allergens/Duck-feathers/ Reference 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(Suppl 3):S1-S148.
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Price:
$49
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Duloxetine, Serum/Plasma
*Build Your Own Panel Eligible [?]
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$494
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Description:
Antidepressant.
Categories:
Price:
$494
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Dystonia (DYT1) DNA Test
*Build Your Own Panel Eligible [?]
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$1300
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Description:
Detects GAG deletion in the DYT1 gene in patient with Dystonia-1, Torsion. Patients exhibit generalized or focal early-onset idiopathic torsion dystonia.
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Price:
$1300
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Eastern Equine Encephalitis Virus Antibodies (IgG, IgM), IFA
*Build Your Own Panel Eligible [?]
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$452
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Description:
IgG titers ≥1: 16 suggest exposure (either past or recent), while the presence of IgM indicated recent infection.
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Price:
$452
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E-Cadherin, IHC with Interpretation
*Build Your Own Panel Eligible [?]
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$428
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Description:
- Analyze tissue samples for cell abnormalities
- Detect changes in cell structure patterns
- Support your biopsy follow-up decisions
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Price:
$428
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Echinococcus Antibody (IgG), EIA with Reflex to Western Blot
*Build Your Own Panel Eligible [?]
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$300
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Description:
Echinococcus IgG detection is an important tool for diagnosing hydatid disease, since infected individuals do not exhibit fecal shedding of E. granulosus eggs.
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Price:
$300
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Echovirus Antibody Panel
*Build Your Own Panel Eligible [?]
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$429
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Description:
The current echovirus panel includes serotypes 4, 7, 9, 11, and 30. The echovirus serotypes used in this panel will vary depending upon current epidemiological data available from inhouse isolations CDC reports. Generally, the serotypes used are those most commonly associated with viral meningitis. Although there is cross-reactivity among the enteroviruses, most healthy people do not have detectable CF titers (>1:8). Therefore, detectable titers, especially those >1:32, should be considered diagnostic. Confirmed serodiagnosis is made by demonstration of a four-fold change in titers between acute and convalescent sera.
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Price:
$429
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Egg Component Panel
*Build Your Own Panel Eligible [?]
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$115
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Description:
For use in the identification and severity of which specific egg protein a patient is allergic. This knowledge enables the clinician and the patient to make the correct treatment and lifestyle choices to mitigate exposure and reaction risk.
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Price:
$115
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Egg Mix (Yolk & White) (f245) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This test detects the presence of specific IgE against egg mix (yolk and white). A positive test only indicates that a person is sensitized and potentially allergic to this allergen. A diagnosis of allergy requires clinical signs and symptoms that appear to be associated with exposure to the allergen in addition to the detection of markers of IgE sensitization [1].More specific information about this allergen can be found on the following website: https://www.thermofisher.com/phadia/us/en/resources/allergen-encyclopedia.htmlReference1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.
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Price:
$49
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Eggplant (f262) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This test quantifies an individual’s IgE response to eggplant. It is an in vitro quantitative assay, which is intended to be used in conjunction with other clinical information to aid in the diagnosis of food allergy [1]. While allergen-specific serum IgE testing is considered comparable to skin testing in many instances, both the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology recognize that allergen-specific serum IgE testing may be preferred in some clinical situations. These include 1) the presence of widespread skin disease, 2) the recent use of antihistamines or other medications that can affect the results of allergy skin tests, 3) uncooperative patients, and 4) medical history suggesting that allergen skin testing would pose a significant risk for a serious allergic reaction [1]. Food-specific IgE tests are extremely sensitive. However, a positive test result only indicates that a patient is IgE sensitized to the food of concern. Many IgE-sensitized patients do not develop any symptoms when this food is ingested. A diagnosis of food allergy should only be made by a trained medical provider, after conducting a thorough clinical evaluation [2,3]. While food-specific IgE test results may contribute to that evaluation, they cannot replace it. In this regard, detection of food-specific IgE in serum provides evidence of IgE sensitization, but a history of clinical reactivity to the food of concern, is required to make a diagnosis of IgE-mediated food allergy. Moreover, several forms of food hypersensitivity are not associated with the presence of food-specific IgE in serum. More specific information about this allergen can be found at http://www.phadia.com/en/products/allergy-testing-products/immunocap-allergen-information/food-of-plant-origin/vegetables/aubergine-eggplant/ References 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(suppl 3):S1-S148. 2. Sampson HA, et al. J Allergy Clin Immunol. 2014;134(5):1016-1025. 3. Boyce JA, et al. J Allergy Clin Immunol. 2010;126(6 suppl):S1-S58.
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Price:
$49
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Egg White (f1) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This test detects the presence of specific IgE against egg whites. A positive test only indicates that a person is sensitized and potentially allergic to this allergen. A diagnosis of allergy requires clinical signs and symptoms that appear to be associated with exposure to the allergen in addition to the detection of markers of IgE sensitization [1].More specific information about this allergen can be found on the following website: https://www.thermofisher.com/phadia/us/en/resources/allergen-encyclopedia.htmlReference1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.
Categories:
Price:
$49
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Egg White (f1) IgE with Reflex to Egg Component Panel
*Build Your Own Panel Eligible [?]
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$49
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Description:
Patients with positive allergen IgE results may not have a true food allergy. Food component IgE tests offer more specific information to better predict the likelihood that a true food allergy exists and other details of potential clinical relevance.
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Price:
$49
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Egg white (f1) IgG
*Build Your Own Panel Eligible [?]
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$118
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Description:
- Detect egg white food sensitivity
- Screen digestive discomfort after eating
- Track skin reactions from food
Categories:
Price:
$118
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Egg Whole IgG4
*Build Your Own Panel Eligible [?]
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$254
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Description:
- Detect possible egg food sensitivity
- Screen digestive discomfort after eggs
- Track immune response to eggs
Categories:
Price:
$254
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Egg Yolk (f75) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This test detects the presence of specific IgE against egg yolk. A positive test only indicates that a person is sensitized and potentially allergic to this allergen. A diagnosis of allergy requires clinical signs and symptoms that appear to be associated with exposure to the allergen in addition to the detection of markers of IgE sensitization [1].More specific information about this allergen can be found on the following website: https://www.thermofisher.com/phadia/us/en/resources/allergen-encyclopedia.htmlReference1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.
Categories:
Price:
$49
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Egg Yolk (f75) IgG
*Build Your Own Panel Eligible [?]
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$118
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Description:
- Check egg yolk sensitivity reactions
- Screen digestive discomfort after eggs
- Identify possible dietary trigger foods
Categories:
Price:
$118
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Ehrlichia chaffeensis Antibodies (IgG, IgM) with Reflex to Titers
*Build Your Own Panel Eligible [?]
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$432
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Description:
This test is for the detection of IgG and IgM antibodies against Ehrlichia chaffeensis to aid in the diagnosis of Ehrlichiosis (human monocytic ehrlichiosis). Ehrlichiosis is a tickborne disease caused by transmission of the bacteria via the bite of an infected tick. It is most common in the eastern to southeastern and south-central United States.Testing for E. chaffeensis is based on a clinical evaluation and risk of tick exposure with consideration to the geographic region. Symptoms may be nonspecific, including headache, fever/chills, malaise, myalgia, gastrointestinal symptoms, and rash. Infection can have similarities with other tickborne illnesses with overlapping vectors, geographic endemicity, and similar clinical signs and symptoms, including Anaplasma spp, Borrelia burgdorferi (Lyme disease) and Babesia microti.Negative results can occur early in infection. Nucleic acid amplification tests are the preferred method for diagnosis during acute infection. Seroconversion or a four-fold increase between acute and convalescent sera can be used to support a diagnosis. The presence of IgG alone may indicate past infection, and IgM may persist for many months after infection has resolved. Antibody levels may remain elevated for several years after acute illness. Cross-reactivity between related organisms Anaplasma and Ehrlichia spp, can occur. Therefore, interpretation of serologic results is done in the context of pertinent clinical picture, including timing from symptom onset.References:1. Tickborne Diseases of the United States. A Reference Manual for Healthcare Providers, Sixth Edition, 2022. Centers for Disease Control and Prevention.2. Clinical Testing and Diagnosis for Ehrlichiosis Centers for Disease Control and Prevention. Last updated May 15, 2024. https://www.cdc.gov/ehrlichiosis/hcp/diagnosis-testing/index.html.3. Miller, MJ. Et al. Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2024 Update by the Infectious Diseases Society of America (IDSA) and the American Society for Microbiology (ASM). Clin Infect Dis. 2024 Mar 5: ciae104.doi: 10.1093/cid/ciae104.4. Biggs, HM, et al. Diagnosis and Management of Tickborne Rickettsial Diseases: Rocky Mountain Spotted Fever and Other Spotted Fever Group Rickettsioses, Ehrlichioses, and Anaplasmosis - United States. MMWR Recomm Rep. 2016 May 13;65(2):1-44.
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Price:
$432
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Ehrlichia chaffeensis DNA, Real-Time PCR
*Build Your Own Panel Eligible [?]
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$724
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Description:
Ehrlichia chaffeensis DNA PCR is a highly sensitive method to detect the presence of ehrlichia chaffeensis DNA in clinical specimens. The diagnosis of ehrlichia chaffeensis infection should not rely solely upon the result of PCR assay. A positive result should be considered in conjunction with clinical presentation and additional established clinical tests. Moreover, this assay cannot differentiate between viable and nonviable organisms. A negative PCR result indicates the absence of ehrlichia chaffeensis DNA at detectable levels in the sample tested and does not exclude the diagnosis of disease.
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Price:
$724
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Ehrlichia ewingii DNA, Real-Time PCR
*Build Your Own Panel Eligible [?]
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$614
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Description:
The Ehrlichia ewingii DNA PCR test is highly sensitive and specific, and can be used to confirm the diagnosis of human ehrlichiosis especially during the acute phase of the disease.
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Price:
$614
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ELANE Genetic Analysis
*Build Your Own Panel Eligible [?]
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$1002
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Description:
ELA2-related neutropenia includes congential and cyclic neutropenia. Both are characterized by recurrent fever, infections and inflammation of the mouth, skin and pharynx. Diagnosis of these disorders is based on clinical findings and serial measurement of the absolute neutrophil count (ANC). Cyclic neutropenia is distinguished from congenital neutropenia by regular oscillations of the anc and generally milder infectious complications. Identification of a mutation in the ELA2 gene confirms a diagnosis of congenital or cyclic neutropenia. ELA2-related neutropenia is inherited in an autosomal dominant manner. ELA2 is the only gene known to cause these disorders. Mutations in ELA2 have been reported in 90-100% of cyclic neutropenia patients and 38-80% of congenital neutropenia patients. The mutation detection rate is highest in patients with the classic clinical symptoms defining these disorders.
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Price:
$1002
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Electrolyte Panel
*Build Your Own Panel Eligible [?]
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$44
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Description:
The Electrolyte Panel is performed to check for kidney problems, acids in your blood, a sodium or potassium problem and diabetes.
Significant deviations from the normal range may require further evaluation by your physician.
Includes:
Carbon Dioxide
Chloride
Potassium
Sodium
**** Electrolyte Panel is included in the Comprehensive Metabolic Profile (CMP) and Kidney Function Profile.***
Patient Instructions:
No fasting needed.
Categories:
Fitness, nutrition, anti-aging,
Hormones & metabolism,
Price:
$44
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Electrolytes, Feces
*Build Your Own Panel Eligible [?]
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$429
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Description:
This panel measures sodium, potassium, and chloride in liquid stool. Measurements of electrolytes and osmotic gap in liquid stool help differentiate between secretory and osmotic diarrhea and, thus, guide further evaluation of chronic diarrhea [1,2].Diarrhea can be categorized as secretory or osmotic depending on how the water content of stool is drawn in the intestine lumen. Secretory diarrhea is caused by defective electrolyte absorption that increases the stool's electrolyte levels. Conditions associated with secretory diarrhea include infection, neuroendocrine tumors, congenital chloridorrhea, intestinal resection, and diffuse mucosal disease [1]. Osmotic diarrhea is caused by the osmotic effect of a substance that retains water in the intestine lumen and leads to decreased electrolyte levels in the stool. Conditions associated with osmotic diarrhea include ingesting poorly absorbed solutes (eg, sorbitol, mannitol, and laxatives containing magnesium) and enzyme dysfunction (eg, lactose intolerance) [2].Osmotic gap, calculated as the difference between the stool osmolality and twice the sum of the stool sodium and potassium levels, is useful in assessing the contribution of stool electrolytes to osmolality and differentiating between secretory and osmotic diarrhea [1,2].A theoretical fecal osmolality, approximately the same as plasma osmolality (290 mOsm/kg), is used in the calculation.Measurement of chloride in liquid stool aids in the diagnosis of congenital or secondary chloridorrhea, which is characterized by increased excretion of chloride in stool. Low levels of chloride in liquid stool may also be seen in sodium sulfate-induced diarrhea [2]. The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.References1. Schiller LR. Pract Res Clin Gastroenterol. 2012;26(5):551-562.2. Block DR, et al. Body fluids. In: Rifai R, et al. eds. Tietz Textbook of Laboratory Medicine. 7th ed. Elsevier Inc; 2022.
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Price:
$429
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Electron Microscopy
*Build Your Own Panel Eligible [?]
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$1901
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Description:
Electron microscopy uses specialized microscopes with a beam of electrons as the source of illumination. Electron optics are analogous to glass lenses of an optical light microscope. Wavelengths of an electron can be up to 100,000 times shorter than that of visible light. Therefore, electron microscopes provide higher resolutions of about 0.1 nm, compared to about 200 nm with light microscopy.
Categories:
Price:
$1901
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Elm, American IgG4
*Build Your Own Panel Eligible [?]
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$254
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Description:
- Identify elm pollen allergy triggers
- Track seasonal sneezing and congestion causes
- Screen for tree pollen immune reactions
Categories:
Price:
$254
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Elm Cedar IgE (ulmus crassifolia)
*Build Your Own Panel Eligible [?]
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$308
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Description:
- Check for elm pollen allergies
- Identify seasonal sneezing triggers
- Screen for tree allergy sensitivity
Categories:
Price:
$308
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Elm (t8) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This test quantifies an individual’s IgE response to elm. It is an in vitro quantitative assay, which is intended to be used in conjunction with other clinical information to aid in the diagnosis of allergic diseases [1]. While allergen-specific serum IgE testing is considered comparable to skin testing in many instances, both the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology recognize that allergen-specific serum IgE testing may be preferred in some clinical situations. These include 1) the presence of widespread skin disease, 2) the recent use of antihistamines or other medications that can affect the results of allergy skin tests, 3) uncooperative patients, and 4) medical history suggesting that allergen skin testing would pose a significant risk for a serious allergic reaction [1]. A definitive clinical diagnosis of allergy should not be based on the results of any single diagnostic method, but should be made by a trained healthcare professional after all clinical and laboratory findings have been evaluated. More specific information about tree pollens can be found at http://www.phadia.com/en/products/allergy-testing-products/immunocap-allergen-information/tree-pollens/allergens/elm-/ Reference 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(suppl 3):S1-S148.
Categories:
Price:
$49
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EML4 ALK Gene Fusion, PCR
*Build Your Own Panel Eligible [?]
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$638
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Description:
Recently, inhibitors of anaplastic lymphoma kinase (ALK) have been used successfully in treating patients harboring gene fusions between echinoderm microtubule-associated protein-like 4 (EML4) and ALK. This is a reverse transcription PCR-based exon scanning approach to encompass fusion variants spanning nearly the entire EML4 gene.
Categories:
Price:
$638
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Encephalitis Antibody Evaluation with Reflex to Titer and Line Blot, Serum
*Build Your Own Panel Eligible [?]
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$15648
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Description:
The Encephalitis Antibody Panel provides an evaluation of possible autoantibodies in patients with suspected autoimmune encephalitis, and optimizes the likelihood of detecting neuronal specific autoantibodies, whether present singly or occurring as multiple autoantibodies.
Categories:
Price:
$15648
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Endomysial Antibody (IgA) Screen with Reflex to Titer
*Build Your Own Panel Eligible [?]
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$207
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Description:
The presence of anti-endomysial (EMA) IgA antibodies has been shown to correlate with gluten-sensitive enteropathy such as celiac disease (CD) and dermatitis herpetiformis (DH). EMA is detected primarily by IFA, using monkey esophagus as a substrate and observing fluorescence of the endomysial lining. Patients with CD and DH can also demonstrate antibodies to reticulin and gliadin, though EMA-IgA seems to be the most specific marker (specifically 94-100%).
Categories:
Price:
$207
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Endomysial (IgG) Antibody Screen and Titer
*Build Your Own Panel Eligible [?]
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$307
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Description:
Serological methods of detecting Immunoglobulin A (IgA) antibodies to gliadin, endomysium (EMA), reticulin, and tissue transglutaminase are routinely used for diagnosing both symptomatic and asymptomatic patients with Celiac Disease (CD). Since Immunoglobulin A (IgA) deficiency is 10 to 15 times more common in patients with Celiac Disease than in healthy subjects, IgG-specific antibody tests for endomysium are useful for the identification of IgA-deficient patients with CD.
Categories:
Price:
$307
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English Plantain (w9) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This test quantifies an individual's IgE response to English plantain. Allergen-specific serum IgE testing is considered comparable to skin testing and may be preferred in some clinical situations. However, a positive test result only indicates that a patient is sensitized to the allergen of concern. Many IgE-sensitized individuals do not develop any symptoms when exposed to the allergen. A diagnosis of allergy should only be made by a trained medical provider after conducting a thorough clinical evaluation [1].More specific information about this allergen can be found on the following website: https://www.thermofisher.com/phadia/us/en/resources/allergen-encyclopedia.htmlReference 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.
Categories:
Price:
$49
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Enhanced Liver Fibrosis (ELF) Score
*Build Your Own Panel Eligible [?]
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$788
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Description:
The Enhanced Liver Fibrosis (ELF) score predicts progression to cirrhosis and liver-related events in patients with advanced fibrosis due to NASH. The ELF score is not for use in the diagnosis of NASH, the staging of fibrosis, the serial monitoring of disease progression, or the monitoring of effects of therapeutic products. The ELF score is derived from an algorithm that combines measurements of PIIINP, TIMP-1, and HA. PIIINP is a marker of early fibrogenesis and inflammation, TIMP-1 is the circulating inhibitor of MMP enzymes that can enhance fibrogenesis, and HA is a glycosaminoglycan that is produced by hepatic stellate cells. Together, these assays measure qualitative and quantitative changes in the extracellular matrix (ECM). The ECM refers to a set of macromolecules that comprise the extracellular scaffolding of the liver. Some ECM markers reflect fibrogenesis and others reflect fibrosis regression, allowing for a dynamic evaluation of ECM activity.
Categories:
Price:
$788
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Entamoeba histolytica Antigen, EIA
*Build Your Own Panel Eligible [?]
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$342
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Description:
Entamoeba histolytica are intestinal parasites that infect a half billion people worldwide annually. Of those infected, most are infected with the non-pathogenic E. dispar, which has not been associated with disease. It is estimated that approximately 10% of the half billion people infected each year are infected with the pathogenic E. histolytica. These individuals become symptomatic and develop colitis and liver abscesses.
Categories:
Price:
$342
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Enterovirus Culture
*Build Your Own Panel Eligible [?]
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$601
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Description:
Enteroviruses are among the most common viruses infecting humans and are associated with diverse clinical syndromes ranging from minor febrile illness to severe, potentially fatal conditions (e.g., aseptic meningitis, encephalitis, paralysis, myocarditis, and neonatal enteroviral sepsis) and could be linked with the development of some chronic diseases (e.g., type 1 diabetes and dilated cardiomyopathy). Each year, an estimated 10 to 15 million symptomatic enterovirus infections occur in the United States.
Categories:
Price:
$601
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Enterovirus Panel, CF, Serum
*Build Your Own Panel Eligible [?]
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$715
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Description:
Detectable titers to enteroviruses, particularly titers >1:32, typically indicate recent infection. Although there is considerable cross-reactivity among enteroviruses, the highest titer is usually associated with the infecting serotype.
Categories:
Price:
$715
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Enterovirus/Parechovirus RNA, Qualitative Real-Time PCR
*Build Your Own Panel Eligible [?]
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$790
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Description:
This broad-spectrum assay detects the genomic RNA of members of the Enterovirus genus (including enteroviruses, echoviruses, coxsackieviruses and polioviruses) as well as the genomic RNA of members of the Parechovirus genus. The use of this assay allows for rapid patient testing as an aid in the diagnosis of viral meningitis or sepsis-like syndromes.
Categories:
Price:
$790
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Enterovirus RNA, Qualitative, Real-Time PCR
*Build Your Own Panel Eligible [?]
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$460
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Description:
Reverse Transcriptase-PCR (RT-PCR) is a highly sensitive method used to detect enterovirus (EV) RNA from various clinical specimens. This assay targets a conserved region of the EV genome which allows detection of nearly the entire spectrum of human enteroviruses, including the coxsackieviruses, polioviruses and the echoviruses. It does not differentiate among the EV serotypes or differentiate EV from rhinovirus. The diagnosis of enterovirus infection should not rely solely upon the result of a RT-PCR assay. A positive result should be considered in conjunction with clinical presentation and additional established clinical tests. A negative RT-PCR result indicates the absence of enterovirus RNA in the sample tested and does not exclude the diagnosis of disease.
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Price:
$460
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Enterovirus RNA, Quantitative Real-Time PCR
*Build Your Own Panel Eligible [?]
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$868
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Description:
The enterovirus (EV) RNA quantitative PCR is a highly sensitive method used to detect and quantify enterovirus (EV) RNA from various clinical specimens. This assay targets a conserved region of the EV genome which allows detection of nearly the entire spectrum of human enteroviruses, including the coxsackieviruses, polioviruses and the echoviruses. Enterovirus D68 is detected. However, this assay does not differentiate among the EV serotypes or differentiate EV from rhinovirus.
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Price:
$868
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Eosinophil Cationic Protein (ECP)
*Build Your Own Panel Eligible [?]
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$351
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Description:
- Checks allergy and asthma activity.
- Measures inflammation from white blood cells.
- Assesses eosinophil-related inflammation.
Includes:
Eosinophil Cationic Protein (ECP)
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Price:
$351
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Eosinophil Count, Blood
*Build Your Own Panel Eligible [?]
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$140
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Description:
- Measures allergy and infection cells
- Checks white blood cell levels
- Helps diagnose allergic reactions
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Price:
$140
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Eosinophil Count, Nasal
*Build Your Own Panel Eligible [?]
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$124
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Description:
Screening test to aid in diagnosis of allergic rhinitis.
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Price:
$124
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Eosinophil Count, Sputum
*Build Your Own Panel Eligible [?]
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$213
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Description:
Screening test to aid in diagnosis of asthma, bronchitis and some types of pneumonia.
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Price:
$213
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Epicoccum purpurascens (m14) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This allergen-specific IgE antibody test quantifies an individual’s IgE response to Epicoccum purpurascens. It is an in vitro quantitative assay that is intended to be used in conjunction with other clinical information to aid in the diagnosis of allergic diseases [1]. While allergen-specific serum IgE testing is considered comparable to skin testing in many instances, both the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology recognize that allergen-specific serum IgE testing may be preferred in some clinical situations. These include 1) the presence of widespread skin disease, 2) the recent use of antihistamines or other medications that can affect the results of allergy skin tests, 3) uncooperative patients, and 4) medical history suggesting that allergen skin testing would pose a significant risk for a serious allergic reaction [1]. A definitive clinical diagnosis of allergy should not be based on the results of any single diagnostic method, but should be made by a trained healthcare provider after all clinical and laboratory findings have been evaluated. More specific information about this allergen can be found at http://www.phadia.com/en/products/allergy-testing-products/immunocap-allergen-information/molds-and-other-microorganisms/allergens/epicoccum-purpurascens/ Reference 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(Suppl 3):S1-S148.
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Price:
$49
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Epidermal Antibodies with Reflex to Titer
*Build Your Own Panel Eligible [?]
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$326
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Description:
The detection of anti-skin antibodies aids in the diagnosis of chronic vesicular-bullous diseases including pemphigus, pemphigoid, cicatricial pemphigoid, and epidermolysis bullosa acquisita (EBA). Epithelial intercellular antibodies are diagnostic for pemphigus and occur in over 90% of sera from all active forms. Antibodies to basement membrane antigens of stratified squamous epithelium occur in about 70% of active bullous pemphigoid, 50% of vesicular pemphigoid and EBA and 10% of cicatricial pemphigoid patients.
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Price:
$326
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Epidermal Growth Factor Receptor (EGFR) Mutation Analysis
*Build Your Own Panel Eligible [?]
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$1172
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Description:
EGFR kinase domain mutations are found in 10-15% of lung adenocarcinomas, particularly those occurring in younger patients without a smoking history, and identify tumors that may have significant clinical response to EGFR-targeted kinase inhibitors. PCR-based DNA sequencing is used to assess for mutations in exons 18-21 of EGFR, which are the sites of greater than 95% of somatic mutations observed in tumors. This assay will also detect the T790M mutation, which is commonly seen in acquired resistance. With this information, physicians will be able to select those patients who are most likely to respond to targeted lung cancer therapy. In addition, follow-up samples from patients with resistant or recurrent disease may demonstrate an acquired T790M mutation, where newer FDA-approved agents have been shown to be effective.
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Price:
$1172
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