HPV DNA (16, 18, Other High Risk), PCR, Cervical
*Build Your Own Panel Eligible [?]
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$342
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Description:
This test is used for the detection of high-risk Human Papillomavirus in clinician-collected cervical samples and can be used as part of an HPV primary screening algorithm. The test detects high-risk HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68, which are reported out as HPV 16, HPV 18, and other high-risk HPV types which includes, but does not differentiate, the remaining 12 high-risk types. Interim guidance supports the use of an HPV primary screening algorithm, where high-risk HPV testing is used as a first line screen, in women ≥25 years of age [1].Patients should be followed-up in accordance with professional medical guidelines, results from prior screening, medial history, and other risk factors.Specimens collected in SurePath collection devices have not been validated for use in HPV primary screening algorithms. If utilizing HPV primary screening algorithms, specimens collected in ThinPrep collection devices are approved by the Food and Drug Administration (FDA).1. Huh WK, Ault KA, Chelmow D, et al. Use of primary high- risk human papillomavirus testing for cervical cancer screening: interim clinical guidance. Obstet Gynecol. 2015;125(2):330-337. doi:10.1097/AOG.0000000000000669
Categories:
Price:
$342
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|
HPV DNA (16, 18, Other High Risk), PCR, Vaginal Self-Collected
*Build Your Own Panel Eligible [?]
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$342
|
|
|
Description:
This test is used for the detection of high-risk Human Papillomavirus in self-collected vaginal samples and can be used as part of an HPV primary screening algorithm. The test detects high-risk HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68, which are reported out as HPV 16, HPV 18, and other high-risk HPV types which includes, but does not differentiate, the remaining 12 high- risk types. Interim guidance supports the use of an HPV primary screening algorithm, where high-risk HPV testing is used as a first line screen, in women ≥25 years of age [1].In patients for whom cervical sampling is either contraindicated or a cervical sample cannot otherwise be obtained, vaginal samples can be self-collected within a healthcare setting where samples can be processed by trained personnel. Patients should be followed-up in accordance with professional medical guidelines, results from prior screening, medical history, and other risk factors.1. Huh WK, Ault KA, Chelmow D, et al. Use of primary high- risk human papillomavirus testing for cervical cancer screening: interim clinical guidance. Obstet Gynecol. 2015;125(2):330-337. doi:10.1097/AOG.0000000000000669
Categories:
Price:
$342
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HPV DNA (16,18, Other High Risk), PCR with Reflex to ThinPrep® Automated Pap
*Build Your Own Panel Eligible [?]
|
$342
|
|
Description:
- Screen for high-risk HPV strains
- Detect early cervical cell changes
- Monitor long-term cervical cancer risk
Categories:
Price:
$342
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|
HPV Genotypes 16, 18/45
*Build Your Own Panel Eligible [?]
|
$317
|
|
Description:
- Detect high-risk HPV cervical cancer strains
- Screen for cervical cancer risk factors
- Monitor your cervical health proactively
Categories:
Price:
$317
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|
HPV Genotypes 16, 18/45, Anal-Rectal
*Build Your Own Panel Eligible [?]
|
$317
|
|
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Description:
Assay is used in combination with anal and rectal cytology to assess the presence or absence of high-risk HPV genotypes 16, 18, and/or 45. This information together with physician's assessment of cytology history, other risk factors and professional guidelines, may be used to guide patient management.
Categories:
Price:
$317
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HPV Genotypes 16, 18/45, Post-Hysterectomy, Vaginal
*Build Your Own Panel Eligible [?]
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$317
|
|
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Description:
Assay is used in combination with cytology to assess the presence or absence of high-risk HPV genotypes 16, 18, and/or 45 in post-hysterectomy patients. This information, together with physician's assessment of cytology history, other risk factors, and professional guidelines, may be used to guide patient management.
Categories:
Price:
$317
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HPV Genotypes 16, 18/45, SurePath™ Vial
*Build Your Own Panel Eligible [?]
|
$317
|
|
Description:
- Screen for high-risk HPV strains
- Check your cervical cancer risk
- Detect HPV before symptoms appear
Categories:
Price:
$317
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HPV mRNA E6/E7, Post-Hysterectomy, Vaginal
*Build Your Own Panel Eligible [?]
|
$317
|
|
|
Description:
May aid in the diagnosis of vaginal cancer.
Categories:
Price:
$317
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|
HPV mRNA E6/E7, Post-Hysterectomy, Vaginal with Reflex to HPV 16, 18/45
*Build Your Own Panel Eligible [?]
|
$317
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|
|
Description:
May aid in the diagnosis of vaginal cancer.
Categories:
Price:
$317
|
|
HPV mRNA E6/E7, Rectal
*Build Your Own Panel Eligible [?]
|
$317
|
|
|
Description:
The HPV mRNA E6/E7 test is used in conjunction with cytology to evaluate anal dysplasia.
Categories:
Price:
$317
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HPV mRNA E6/E7, Rectal with Reflex to Genotypes, 16, 18/45
*Build Your Own Panel Eligible [?]
|
$317
|
|
|
Description:
The HPV mRNA E6/E7 test is used in conjunction with cytology to evaluate anal dysplasia.
Categories:
Price:
$317
|
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HPV mRNA E6/E7, SurePath™ Vial
*Build Your Own Panel Eligible [?]
|
$317
|
|
Description:
- Screen for high-risk HPV infection
- Detect early cervical cell change risk
- Monitor abnormal Pap test follow-up
Categories:
Price:
$317
|
|
HPV mRNA E6/E7, SurePath™ Vial reflex HPV 16,18/45
*Build Your Own Panel Eligible [?]
|
$317
|
|
Description:
- Screen for high-risk cervical cancer virus
- Detect early HPV infection signs
- Monitor cervical health over time
Categories:
Price:
$317
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HPV mRNA E6/E7 with Reflex to HPV Genotypes 16, 18/45
*Build Your Own Panel Eligible [?]
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$317
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|
|
Description:
The presence of E6/E7 messenger RNA from 14 high risk HPV types indicates incorporation of HPV DNA into the host cells. Proteins expressed from E6-E7 polycistronic mRNA alter cellular p53 and retinoblastoma protein functions, leading to disruption of cell-cycle check points and cell genome instability. This information, together with the physicians assessment of cytology history, other risk factors, and professional guidelines, may be used to guide patient management. This assay detects E6/E7 viral messenger RNA (mRNA) from 14 high-risk HPV types (16,18,31,33,35,39,45,51,52,56,58, 59,66,68).
Categories:
Price:
$317
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|
HPV RNA, Low and High Risk, ISH
*Build Your Own Panel Eligible [?]
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$790
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Description:
HPV is the causative agent of cervical dysplasia and carcinoma. Selected low-risk and high-risk subtypes are assessed in tissue block.
Categories:
Price:
$790
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H. Pylori Antigen Stool
*Build Your Own Panel Eligible [?]
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$216
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Description:
Colonization with H. pylori is associated with increased risk of patients developing gastritis, peptic ulcer disease, and gastric adenocarcinoma. Stool antigen testing provides a sensitive measure of infection including during and after treatment.
Significant deviations from the normal range may require further evaluation by your physician.
Includes:
H. Pylori AG Stool
Alternative Name(s):
H. pylori Antigen, H. pylori Stool Antigen
Patient Instructions:
Collect 0.5 mL or 0.5 grams of semi-solid stool or 20 mm diameter solid stool and transfer to properly labeled plastic, leak-proof container. Do not place stool in preservative, transport media or swab. Watery, diarrheal stool is not acceptable. It is recommended that you contact the Patient Service Center to verify appropriate container for submitting stool specimen. It may be required that you go to the lab and pickup a container to submit your stool specimen.
For initial diagnostic purposes no special patient preparation is required. Patients are not required to be off of medications or to fast before this test. While positive test results from patients taking agents such as proton pump inhibitors and antimicrobials should be considered accurate, false negative results may be obtained. For this reason, physicians may suggest the patient go off medications for two weeks and repeat test if negative results are obtained.
To confirm eradication, testing should be done at least 4 weeks following the completion of treatment. However, a positive test result 7 days post therapy is indicative of treatment failure. Watery, diarrheal stool is not acceptable.
Categories:
Gastrointestinal diseases,
Price:
$216
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H. Pylori Screening (Advanced) Stool
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$226
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Description:
Helicobacter pylori (H. pylori) is a bacteria that can cause stomach irritation (gastritis), heartburn, nausea and bloating (dyspepsia), and ulcers in the stomach and intestine. H. pylori may also be a factor in the development of stomach cancer. Colonization with H. pylori is associated with increased risk of patients developing gastritis, peptic ulcer disease, and gastric adenocarcinoma. Stool antigen testing provides a sensitive measure of infection including during and after treatment.
Abnormal results may require further evaluation by your physician.
Includes:
Complete Blood Count / CBC (includes Differential and Platelets): WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet Count, MPV and Differential (Absolute and Percent - Neutrophils, Lymphocytes, Monocytes, Eosinophils, and Basophils)
C-Reactive Protein (CRP)
H. Pylori AG Stool
Patient Instructions:
Collect 0.5 mL or 0.5 grams of semi-solid stool or 20 mm diameter solid stool and transfer to properly labeled plastic, leak-proof container. Do not place stool in preservative, transport media or swab. Watery, diarrheal stool is not acceptable. It is recommended that you contact the Patient Service Center to verify appropriate container for submitting stool specimen. It may be required that you go to the lab and pickup a container to submit your stool specimen.
For initial diagnostic purposes no special patient preparation is required. Patients are not required to be off of medications or to fast before this test. While positive test results from patients taking agents such as proton pump inhibitors and antimicrobials should be considered accurate, false negative results may be obtained. For this reason, physicians may suggest the patient go off medications for two weeks and repeat test if negative results are obtained.
To confirm eradication, testing should be done at least 4 weeks following the completion of treatment. However, a positive test result 7 days post therapy is indicative of treatment failure.
Categories:
Gastrointestinal diseases,
Price:
$226
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Hu Antibody Screen with Reflex to Titer and Western Blot
*Build Your Own Panel Eligible [?]
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$415
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Description:
Paraneoplastic Syndrome involves non-metastatic systemic effects that accompany malignant disease. Antineuronal Nuclear Antibody (Anti-Hu) is found in 5-10% of patients with small cell carcinoma of the lung. Anti-Hu is associated with subacute syndrome of encephalomyeloradiculopathy, sensory neuropathy, and autoimmune neuropathy, predominantly affecting the gastrointestinal tract.
Categories:
Price:
$415
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Human Growth Hormone
*Build Your Own Panel Eligible [?]
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$84
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|
Description:
Growth Hormone tests are performed to screen for abnormal pituitary functions and also to test for the use of performance enhancing steroids. Measurement of GH is primarily of interest in the diagnosis and treatment of various forms of inappropriate growth hormone secretion.
A significant deviation from the normal range may require further evaluation by your physician.
Alternative Name(s):
Growth Hormone (hGH), HGH, GH
Includes:
Growth Hormone, Serum.
Patient Instructions:
Patient must fast overnight before test and rest for at least 30 minutes prior to test (No strenuous exercise for 30 minutes before the test).
Estimated turnaround for results is 5 business days. If confirmation testing is required, the estimated time may be extended.
Categories:
Fitness, nutrition, anti-aging,
Hormones & metabolism,
Price:
$84
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Human Metapneumovirus RNA, Qualitative, Real-Time PCR
*Build Your Own Panel Eligible [?]
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$770
|
|
Description:
- Detect respiratory virus causing cough symptoms
- Screen for common cold-like illness causes
- Identify infection source before it spreads
Categories:
Price:
$770
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Human Placental Lactogen (hPL)
*Build Your Own Panel Eligible [?]
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$358
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Description:
Human placental lactogen (hPL; chorionic somatomammotropin) is a 21,000 KD polypeptide produced during pregnancy by placental trophoblastic cells. The level of hPL in maternal serum is directly related to placental function and fetal well-being. hPL is detected at about 6 weeks after conception and its concentration increases gradually to peak levels (without decreases) until about the 34th week where it remains stable for the remainder of the pregnancy. Consistently low levels throughout pregnancy or a sudden drop in serial determinations are an indication of fetal distress. After normal delivery, the hPL concentration falls rapidly to an undetectable level. The hPL levels in serum of women with multiple placenta pregnancies generally exceeds that of single placenta pregnancies. This is generally noted from the 2nd trimester to delivery.
Categories:
Price:
$358
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Human Platelet Antigen 1 Genotype
*Build Your Own Panel Eligible [?]
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$625
|
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Description:
Human Platelet Antigen (HPA) polymorphism can lead to alloimmunization that clinically can manifest as neonatal alloimmune thrombocytopenia or post-transfusion thrombocytopenia purpura. HPA-1 genotyping allows screening for potential neonatal immunization in pregnancy.
Categories:
Price:
$625
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Human T-Cell Lymphotropic Virus I, II (HTLV-I/HTLV-II) Antibodies, Preliminary Test W/ Confirmation
*Build Your Own Panel Eligible [?]
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$287
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|
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Description:
Human T-lymphotropic virus (HTLV) is a human retrovirus that causes T-cell leukemia and T-cell lymphoma as well as other diseases. HTLV can be transferred via sexual intercourse and by intravenous drug users. This test will screen patients for infection with human T-lymphotropic virus and, if positive, confirm infection with either HTLV-I or HTLV-II.
A significant deviation from the normal range may require further evaluation by your physician.
Includes:
Human T-Cell Lymphotropic Virus I, II (HTLV-I/HTLV-II) Antibodies, Preliminary Test W/ Confirmation
Note: Confirmation testing is performed on reactive results only if initial values fall within a designated range requiring additional confirmation.
Categories:
STD’s detection & monitoring,
Price:
$287
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Human T-Cell Lymphotropic Virus I, II (HTLV-I/HTLV-II), Qualitative
*Build Your Own Panel Eligible [?]
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$274
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Description:
HTLV-1, a human type C retrovirus, is associated with adult T-cell leukemia, tropical spastic paraparesis, and other demyelinating and neoplastic conditions. More recently, HTLV-1 infection has been shown to be associated with T- and B-cell chronic lymphocytic leukemias (CLL), multiple myeloma, some cases of non-Hodgkin lymphoma, polymyositis, arthritis, Kaposi sarcoma, uveitis, strongyloidiasis, and mycosis fungoides.
HTLV-I/II DNA PCR is a highly specific and sensitive method used to detect HTLV-I/II proviral DNA in clinical specimens. In addition, the assay can also differentiate between HTLV-I and HTLV-II infected individuals.
Includes:
Human T-Cell Lymphotropic Virus I, II (HTLV-I/HTLV-II), Qualitative
Alternative Name(s)
Human T Lymphotropic Virus Type I/II DNA, Qualitative, Real-Time PCR
Categories:
STD’s detection & monitoring,
Price:
$274
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Human Transforming Growth Factor beta 1 (TGF-b1)
*Build Your Own Panel Eligible [?]
|
$287
|
|
|
Description:
Human Transforming Growth Factor beta 1 (TGF-b1) - Transforming Growth Factor (TGF) plays a crucial role in tissue regeneration, cell differentiation, embryonic development, and regulation of the immune system. Transforming growth factor beta is found in hematopoietic (blood-forming) tissue and initiates a signaling pathway that suppresses the early development of cancer cells. It enhances the deposition of extracellular matrix and may play potential role in wound healing and cirrhosis formation. Many cells synthesize TGF-b and almost all of them have specific receptors for this peptide.
Includes:
Human Transforming Growth Factor beta 1 (TGF-b1)
Categories:
Price:
$287
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Human Transforming Growth Factor beta 1 (TGF-b1)
*Build Your Own Panel Eligible [?]
|
$287
|
|
Description:
- Measures cell growth control protein
- Checks body's healing and repair protein
- Analyzes immune system regulation protein
Includes:
Human Transforming Growth Factor beta 1 (TGF-b1)
Categories:
Price:
$287
|
|
Huntington Disease Mutation Analysis
*Build Your Own Panel Eligible [?]
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$772
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Description:
To confirm the clinical diagnosis of Huntington disease (HD) in affected individuals; to provide pre-symptomatic predictive diagnosis of HD in individuals with positive family history; to identify individuals at risk of having affected offspring. This testing methodology may not detect repeat expansions with more than 105 CAG repeats resulting in apparent homozygosity for smaller allele. Large repeat expansion sizes are associated with juvenile onset Huntington's disease.
Categories:
Price:
$772
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Hu, Yo, and Ri Antibodies with Reflex to Titers and Western Blot
*Build Your Own Panel Eligible [?]
|
$843
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Description:
Hu anti-neuronal nuclear antibody (anti-Hu) is found in 5-10% of patients with small cell carcinoma of the lung. Purkinje cell (Yo) antibody is found in patients with paraneoplastic cerebellar degeneration and is associated with breast, ovarian, and other gynecologic cancers. Some patients with ovarian cancer have low titers of Yo antibodies in the absence of cerebellar degeneration. Anti-Hu antibodies are associated with paraneoplastic encephalomyelitis and sensory neuropathy. Anti-Ri antibody can be detected in patients with paraneoplastic opsoclonus/myoclonus syndrome. Neoplasms most often associated with anti-Ri include breast cancer, small cell lung cancer, and gynecological cancers.
Categories:
Price:
$843
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Hyaluronic Acid, Serum
*Build Your Own Panel Eligible [?]
|
$434
|
|
Description:
- Check joint stiffness and discomfort causes
- Assess skin hydration and elasticity levels
- Monitor connective tissue and aging changes
Categories:
Price:
$434
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Hydrocodone and Metabolite, Serum
*Build Your Own Panel Eligible [?]
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$350
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Description:
Therapeutic drug monitoring and confirmation of screen- positive results. Hydrocodone is an active component of Vicodin®, Lorcet®, Lortab®, etc. Serum half-life is 3.4 to 8.8 hours. Hydromorphone is an active ingredient in Dilaudid®. Serum half-life is 1.5 to 3.8 hours.
Categories:
Price:
$350
|
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Hydroxychloroquine, Blood
*Build Your Own Panel Eligible [?]
|
$560
|
|
Description:
- Check your hydroxychloroquine medication levels
- Monitor treatment dosing consistency over time
- Screen for medication under or overdosing
Categories:
Price:
$560
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Hydroxyproline, Plasma
*Build Your Own Panel Eligible [?]
|
$301
|
|
Description:
- Checks bone collagen formation levels.
- Monitors bone growth and healing.
- Assesses osteoporosis treatment effectiveness.
Includes:
Hydroxyproline, Plasma
Patient Instructions:
Overnight fast preferred (or at least 4 hours after a meal).
Categories:
Price:
$301
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|
Hydroxyzine and Metabolite, Urine
*Build Your Own Panel Eligible [?]
|
$428
|
|
|
Description:
Therapeutic drug monitoring.
Categories:
Price:
$428
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Hyperglycosylated hCG (h-hCG)
*Build Your Own Panel Eligible [?]
|
$429
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Description:
Hyperglycosylated hCG (h-hCG), formerly known as ITA, as a single analyte can be used as a marker for detecting pregnancy in the early weeks of gestation. For use in first and second trimester screening, please see the First Trimester Maternal Serum Screen or the Penta Screen, respectively.
Categories:
Price:
$429
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Hypersensitivity Pneumonitis Evaluation
*Build Your Own Panel Eligible [?]
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$935
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Description:
Support the clinical diagnosis of hypersensitivity pneumonitis.
Categories:
Price:
$935
|
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Hypersensitivity Pneumonitis Screen
*Build Your Own Panel Eligible [?]
|
$298
|
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Description:
A diagnosis of Hypersensitivity Pneumonitis (an inflammatory lung disease) may be supported by detection of precipitating antibodies to a variety of inhaled antigens associated primarily with molds, bacteria and birds. A positive test does not always indicate active disease and a diagnosis should be supported by historical and clinical evidence, since healthy individuals occasionally might also develop precipitins. A negative test does not preclude a diagnosis of hypersensitivity pneumonitis and should be considered in the context of other laboratory results and clinical findings.
Categories:
Price:
$298
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Hypoglycemic Panel, Serum/Plasma
*Build Your Own Panel Eligible [?]
|
$666
|
|
Description:
- Check blood sugar drop episodes
- Detect shakiness and fatigue causes
- Monitor energy crashes after meals
Categories:
Price:
$666
|
|
IA-2 Antibody
*Build Your Own Panel Eligible [?]
|
$404
|
|
|
Description:
Key clinical use and differentiatorsMeasurement of Islet cell antigen 2 antibodies (IA-2) is used to: 1. Screen for presymptomatic T1D in individuals with a family history of type 1 diabetes (T1D) or those known to have a high-risk HLA genotype, 2. Distinguish between T1D, type 2 diabetes mellitus (T2D), and atypical forms of diabetes such as latent autoimmune diabetes in adults (LADA). [1] Positivity to IA-2 represents a key marker of T1D. [1]Intended Clinical UseThis test is crucial for differentiating between T1D and T2D. It is important to note that classifying diabetes type can be challenging at the time of presentation, and misdiagnosis can occur in approximately 40% of adults with new T1D. [1]Identifying individuals affected by stage 1 T1D is important for applying eligibility criteria to drugs, such as Teplizumab, which have demonstrated the ability to delay the transition of stage 1 to stage 3 T1D in clinical trials. [2,3]IA-2 has some distinctive features. Its presence is associated with more-advanced islet autoimmunity and faster progression to stage 3 T1D. [4]LimitationsT1D is classified into three stages, with stages 1 and 2 considered presymptomatic. Since the presence of stage 1 and 2 T1D requires at least two islet autoantibodies, relying solely on IA-2 as a screening test limits the ability to make an accurate diagnosis. Professional organizations, including the American Diabetes Association (ADA), recommend using tests for all four islet cell autoantibodies: IAA, glutamic acid decarboxylase (GAD65), Zinc Transporter 8 (ZnT8), and islet cell antigen 2 antibody (IA-2). [1]References1. American Diabetes Association Professional Practice C. 2. Diagnosis and Classification of Diabetes: Standards of Care in Diabetes-2025. Diabetes Care. 2025;48:S27-S49. doi: 10.2337/dc25-S0022. Herold KC, Gitelman SE, Gottlieb PA, Knecht LA, Raymond R, Ramos EL. Teplizumab: A Disease-Modifying Therapy for Type 1 Diabetes That Preserves beta-Cell Function. Diabetes Care. 2023;46:1848-1856. doi: 10.2337/dc23-06753. Ramos EL, Dayan CM, Chatenoud L, Sumnik Z, Simmons KM, Szypowska A, Gitelman SE, Knecht LA, Niemoeller E, Tian W, et al. Teplizumab and beta-Cell Function in Newly Diagnosed Type 1 Diabetes. N Engl J Med. 2023;389:2151-2161. doi: 10.1056/NEJMoa23087434. Decochez K, De Leeuw IH, Keymeulen B, Mathieu C, Rottiers R, Weets I, Vandemeulebroucke E, Truyen I, Kaufman L, Schuit FC, et al. IA-2 autoantibodies predict impending type 1 diabetes in siblings of patients. Diabetologia. 2002;45: 1658-1666. doi: 10.1007/s00125-002-0949-8
Categories:
Price:
$404
|
|
Ibuprofen, Serum/Plasma
*Build Your Own Panel Eligible [?]
|
$352
|
|
Description:
- Check ibuprofen levels in blood
- Detect possible medication overdose signs
- Monitor pain reliever use safely
Categories:
Price:
$352
|
|
IgA
*Build Your Own Panel Eligible [?]
|
$89
|
|
|
Description:
Increased IgA is associated with monoclonal IgA myeloma, respiratory and gastrointestinal infections, and malabsorption; decreased IgA is found in selective IgA deficiency and in ataxia telangiectasia.
Alternative names: Immunoglobulin A
Patient Instructions:
No fasting needed.
Categories:
Gastrointestinal diseases,
Infectious diseases,
Cancer detection,
Pediatrics,
Price:
$89
|
|
IgA, IHC with Interpretation
*Build Your Own Panel Eligible [?]
|
$442
|
|
|
Description:
The following CD markers are expressed on specific hemotologic cells. Individual and a series of IHC markers can be run on unknown cells and presence or absence of the antigen can help to characterize the cell of interest.
Categories:
Price:
$442
|
|
IgA Subclasses
*Build Your Own Panel Eligible [?]
|
$406
|
|
|
Description:
IgA, the predominant immunoglobulin secreted at mucosal surfaces, consists of 2 subclasses. IgA1 is the major subclass and accounts for 80% of total IgA in serum, whereas IgA2 is the major subclass in secretions such as milk.Low concentrations of IgA2 with normal IgA1 levels suggest an IgA2 deficiency.Antigenic sites on the IgA subclasses are responsible for the anaphylactic transfusion reactions experienced by some patients totally deficient in either IgA1 or IgA2. After repeated transfusions, such patients may produce antibodies to these antigens. Thus, IgA subclasses are useful in evaluating patients with anaphylactic transfusion reactions.Elevated concentrations of IgA2 with normal or low amounts of IgA1 suggest a clonal plasma cell proliferative disorder secreting a monoclonal IgA2. Grossly elevated levels of either subclass can occur in patients with IgA myeloma.IgA subclasses are of further importance in certain pathogenic microorganisms, including Haemophilus influenzae, which are capable of enzymic cleavage of IgA1, leading to partial inactivation of this subclass. Recurrent sinopulmonary infections may, therefore, be related to deficiency of IgA2, which is resistant to these organisms.
Categories:
Price:
$406
|
|
IgD
*Build Your Own Panel Eligible [?]
|
$376
|
|
|
Description:
IgD (molecular weight 185 kD) is one of the 5 classes of human immunoglobulins. IgD accounts for less than 1% of the total plasma immunoglobulins. Very high serum IgD concentrations can be found in multiple myeloma patients. Raised levels are also found in hyperimmunoglobulinemia IgD syndrome (HIDS).
Categories:
Price:
$376
|
|
IgD, IHC with Interpretation
*Build Your Own Panel Eligible [?]
|
$388
|
|
Description:
- Assess tissue samples for immune markers
- Screen for specific cell abnormalities
- Support your diagnostic workup process
Categories:
Price:
$388
|
|
IgE
*Build Your Own Panel Eligible [?]
|
$69
|
|
Description:
- Measures allergy-related antibodies level.
- Detects body's allergic reactions.
- Identifies potential allergic sensitivities.
Includes:
IgE
Categories:
Price:
$69
|
|
IgE
*Build Your Own Panel Eligible [?]
|
$69
|
|
|
Description:
For diagnosis of allergic disease. A normal IgE level does not exclude the possible presence of an allergic disorder.
Alternative names: Immunoglobulin E
Categories:
Pediatrics,
General wellness,
Price:
$69
|
|
IgE Antibody (Anti-IgE IgG)
*Build Your Own Panel Eligible [?]
|
$253
|
|
|
Description:
Chronic urticaria is a common skin disorder affecting 1 to 6% of the general population. It is characterized by repeated occurrence of short-lived cutaneous wheals accompanied by redness and itching. Autoimmune urticaria is defined by the presence of a functional IgG antibody to high-affinity IgE receptor (Fc epsilon RI alpha) or to IgE. These antibodies trigger mast cell and basophil degranulation by the engagement of Fc epsilon receptor. Functional IgG antibody to the receptor has been identified in approximately 30-40% of patients with chronic urticaria, and anti-IgE antibody has been identified in another 5% to 10%. The anti-IgE assay will quantify autoantibodies to IgE which will aid in the diagnosis and management of autoimmune chronic urticaria.
Categories:
Price:
$253
|
|
IGF-2
*Build Your Own Panel Eligible [?]
|
$338
|
|
|
Description:
IGF-2 measurements are useful in the diagnosis of growth disorders, as an adjunct to IGF-1.
Patient Instructions:
Overnight fasting is preferred
Categories:
Price:
$338
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IGF Binding Protein-1 (IGFBP-1)
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$320
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Description:
The concentration of IGFBP-1 is correlated with glycemic conditions. IGFBP-1 may be used for monitoring insulin responsiveness, as a marker for insulin-producing tumors, monitoring acute fluctuations in insulin action, and determining if poor glycemic control is due to inadequate insulin treatment or poor control of dietary intake.
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Price:
$320
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IGF Binding Protein-2 (IGFBP-2)
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$294
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Description:
This test measures serum concentration of insulin-like growth factor binding protein 2 (IGFBP-2). The value of testing IGFBP-2 has been researched for various disorders, including obesity, type 2 diabetes, cancer, and Alzheimer disease [1,2].IGFBP-2 belongs to the IGFBP family of 6 proteins that bind and transport insulin-like growth factors (IGFs) and regulate IGF bioavailability. IGFBP-2 is present in very high concentrations during fetal development, progressively falling after birth. Among the 6 IGFBPs, IGFBP-2 has been involved in the IGF activity in most organs, and its role, either dependent or independent of IGFs, has been implicated in bone growth, metabolism, and malignancy [1].The clinical application of IGFPB-2 measurement was explored in numerous studies but has not been well-established. IGFBP-2 is the most abundantly expressed IGFBPs in several cancers, such as glioma, prostate, breast, and ovarian cancers, possibly contributing to the aggressiveness of these cancers [1]. Low levels of IGFBP-2 are associated with obesity, type 2 diabetes mellitus, and metabolic syndrome [1]. The therapeutic potential of IGFPB-2 has been investigated preclinically in increasing insulin sensitivity, decreasing adipogenesis, and inhibiting tumor growth and metastasis.Additionally, IGFBP-2 levels were correlated with cognitive outcomes, possibly by inhibiting the neuroprotective effects of IGFs in the brain. Cognitively healthy adults with elevated levels of IGFBP-2 may have higher risk to develop all-cause dementia and Alzheimer disease dementia [2]. Therefore, IGFBP-2 has been suggested as a potential risk predictor and therapeutic candidate for dementia [2].The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.References1. Yau SW, et al. J Cell Commun Signal. 2015;9(2):125-142.2. McGrath ER, et al. Ann Clin Transl Neurol. 2019;6(9):1659-1670.
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Price:
$294
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