Neurology Antibody, Line Blot
*Build Your Own Panel Eligible [?]
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$5414
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Description:
Western line blot aids in the identification of specific anti-neuronal autoantibodies which can help establish a paraneoplastic syndrome diagnosis and may aid identification of the likely underlying tumor. The most commonly associated malignancies include small cell lung, breast and ovarian cancers, and hematologic malignancies. Clinical presentation of a given antibody may differ amongst patients; different antibodies may cause similar or identical clinical presentations. Paraneoplastic antibodies may be found in the absence of identifiable tumor.
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Price:
$5414
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Neuron Specific Enolase (NSE), Serum
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$310
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Description:
Quantitative determination of NSE in serum may be valuable in the management of patients with suspected or diagnosed SCLC or neuroblastoma, to monitor the effect of treatment, to aid in the detection of recurrent disease, and to evaluate prognosis in patients.
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Price:
$310
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Neutrophil Antibody, Flow Cytometry
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$460
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Description:
Neutrophil Antibody has been observed with neonatal alloimmune neutropenia, autoimmune neutropenia, transfusion reactions, and drug-induced neutropenia.
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Price:
$460
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Neutrophil Function, Oxidative Burst
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$393
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Description:
This assay measures the capability of neutrophils (PMN) to undergo oxidative metabolism to produce superoxide anion and hydrogen peroxide, as detected by oxidation of dihydrorhodamine (DHR). Patients with chronic granulomatous disease (CGD) are unable to oxidize DHR due to defects in oxidative capacity slowly decreases as the specimen age (hours post collection) increases. It is thus important that the reference range value appropriate for the specimen age be utilized when assessing the reported results.
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Price:
$393
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Nevoid Basal Cell Carcinoma (NBCCS) (Gorlin) Syndrome Panel (PTCH1, SUFU)
*Build Your Own Panel Eligible [?]
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$1108
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Description:
A pathogenic variant in the PTCH1 or SUFU genes is consistent with a diagnosis of nevoid basal cell carcinoma syndrome (NBCCS), or Gorlin syndrome. Individuals with NBCCS due to PTCH1 have an elevated risk of basal cell carcinoma (up to 90% by age 50) and medulloblastoma (up to 5% lifetime risk). Individuals also have an elevated risk of jaw keratocysts (up to 90% lifetime risk) and cardiac and ovarian fibromas. Individuals with NBCCS due to SUFU have an elevated risk of medulloblastoma (up to 33% lifetime risk), basal cell carcinoma, and meningioma.
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Price:
$1108
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NF1 Sequencing and Deletion/Duplication
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$628
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Description:
Mutations within the NF1 gene are associated with Neurofibromatosis Type 1. This condition is characterized by an increased risk for neurofibromas, malignant peripheral nerve sheath tumors, pheochromocytoma, and female breast cancer. This test detects pathogenic variants in the NF1 gene.
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Price:
$628
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Nickel, 24-Hour Urine
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$395
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Description:
Nickel toxicity is associated with allergy, asthma, urticaria, erythema multiforme, contact dermatitis, and hand eczema.
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Price:
$395
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Nickel, Blood
*Build Your Own Panel Eligible [?]
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$287
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Description:
Exposure monitoring/investigation.
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Price:
$287
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Nickel, Nails
*Build Your Own Panel Eligible [?]
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$692
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Description:
- Detect nickel-related skin irritation causes
- Screen for common metal contact allergies
- Identify triggers behind recurring rashes
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Price:
$692
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Nickel, Random Urine
*Build Your Own Panel Eligible [?]
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$398
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Description:
Nickel toxicity is associated with allergy, asthma, urticaria, erythema multiforme, contact dermatitis, and hand eczema.
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Price:
$398
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Nickel, Serum/Plasma
*Build Your Own Panel Eligible [?]
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$287
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Description:
- Check nickel exposure in your blood
- Screen for metal-related skin reactions
- Monitor workplace toxin exposure levels
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Price:
$287
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Nicotine and Cotinine, LC/MS/MS, Urine
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$105
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Description:
This assay is used for the detection of nicotine and cotinine in urine to determine the tobacco exposure status of the individual. Nicotine has a short half-life of approximately forty minutes; Its presence may indicate recent tobacco exposure. Cotinine, the major nicotine metabolite, has a half-life of 24 hours and is detectable for several days after cessation of tobacco exposure.
Includes:
Nicotine and Cotinine
Categories:
Nicotine blood testing,
Price:
$105
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Nicotine and Cotinine, Serum/Plasma
*Build Your Own Panel Eligible [?]
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$286
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Description:
This assay is used for the detection of nicotine and cotinine in serum and plasma to determine the tobacco exposure status of the individual. Nicotine has a short half-life of approximately forty minutes; its presence may indicate recent tobacco exposure. Cotinine, the major nicotine metabolite, has a half-life of 24 hours and is detectable for several days after cessation of tobacco exposure.
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Price:
$286
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Nicotine and Expanded Metabolites, LC/MS/MS
*Build Your Own Panel Eligible [?]
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$286
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Description:
This assay is used for the detection of nicotine and two primary metabolites, 3-OH cotinine and cotinine in serum and plasma to determine the tobacco exposure status of an individual. Nicotine has a short half-life of approximately sixty minutes; Its presence may indicate recent tobacco exposure. The half-life of the primary metabolites is longer and provides a larger window of detection for tobacco exposure. Individuals exposed to passive tobacco smoke (environmental or second-hand) can have detectable concentrations of nicotine and its metabolites depending on the type of exposure. The ranges of concentrations related to passive exposure are not well established but normally are less than those attributed to active tobacco users.
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Price:
$286
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Nicotine and Expanded Metabolites, LC/MS/MS, Urine
*Build Your Own Panel Eligible [?]
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$286
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Description:
This assay is used for the detection of nicotine and several metabolites and the related alkaloid anabasine in urine to determine the tobacco exposure status of the individual. Nicotine has a short half-life of approximately sixty minutes; Its presence may indicate recent tobacco exposure. The half-life of the various nicotine metabolites is longer and provides a larger window of detection for tobacco exposure. The presence of anabasine is indicative of tobacco exposure (smoked or smokeless) versus the use of a nicotine replacement patch product. Anabasine is a related alkaloid found only in the tobacco plant. Individuals exposed to passive tobacco smoke (environmental or second-hand) can have detectable concentrations of nicotine and its metabolites depending on the type of exposure. The ranges of concentrations related to passive exposure are not well established but normally are less than those attributed to active tobacco users.
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Price:
$286
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Niemann-Pick Disease Mutation Analysis
*Build Your Own Panel Eligible [?]
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$549
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Description:
Niemann-Pick Disease, a debilitating and fatal disease, is caused by an inherited deficiency of the enzyme acid sphingomyelinase. Niemann-Pick Disease is an autosomal recessive disease with a carrier rate of 1 in 90 among Ashkenazi Jews and a much lower carrier rate in other populations. Mutation analysis detects greater than 95% of mutations described in the Ashkenazi Jewish population.
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Price:
$549
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Nitrogen, Total, Feces
*Build Your Own Panel Eligible [?]
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$577
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Description:
- Check protein digestion and absorption issues
- Detect nutrient malabsorption warning signs
- Monitor unexplained weight loss causes
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Price:
$577
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NKX3.1, IHC with Interpretation
*Build Your Own Panel Eligible [?]
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$442
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Description:
Prostate specific protein, sensitive and specific marker useful in identifying prostate adenocarcinoma.
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Price:
$442
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NKX 3.1, IHC without Interpretation
*Build Your Own Panel Eligible [?]
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$370
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Description:
Prostate specific protein, sensitive and specific marker useful in identifying prostate adenocarcinoma.
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Price:
$370
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NMDA Receptor (NR1-subunit) Autoantibody Test
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$996
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Description:
Anti-NMDA receptor (NR1-subunit) antibody is found in patients with encephalitis, acute psychiatric disturbances, seizures, memory deficits, and hypoventilation.
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Price:
$996
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NMO Spectrum Evaluation (AQP4 with Reflex to MOG), Serum
*Build Your Own Panel Eligible [?]
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$1187
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Description:
NMO (neuromyelitis optica, Devic disease) is an immune- mediated chronic inflammatory disease that predominantly affects the optic nerve and spinal cord and presents with optic neuritis (ON) and myelitis. Limited forms of this disease, such as isolated ON, brainstem encephalitis and longitudinal extensive transverses myelitis (LETM), have been referred to as NMO spectrum disorders (NMOSD). NMO was originally thought to be a variant of multiple sclerosis but is now recognized as a distinct disease. The presence of serum antibodies against aquaporin-4 (AQP4) or myelin oligodendrocyte glycoprotein (MOG-IgG) is associated with NMO and NMOSD.
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Price:
$1187
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Nonesterified Fatty Acids (Free Fatty Acids)
*Build Your Own Panel Eligible [?]
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$349
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Description:
The Nonesterified Fatty Acids (Free Fatty Acids) assay is useful in evaluating lipolysis and fatty acid oxidation. Nonesterified Fatty Acids may be useful in evaluating patients with hypoglycemia and for nutritional assessment.
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Price:
$349
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Non-Melanoma Cancer Blood Scan
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$156
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Description:
- Detect early signs of non-melanoma cancers
- Reveal hidden health issues effortlessly
- Clarify unexplained symptoms with precision
Includes:
Complete Blood Count / CBC (includes Differential and Platelets): WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet Count, MPV and Differential (Absolute and Percent - Neutrophils, Lymphocytes, Monocytes, Eosinophils, and Basophils) Comprehensive Metabolic Profile ( includes eGFR ): Albumin, Albumin/Globulin Ratio (calculated), Alkaline Phosphatase, ALT, AST, BUN/Creatinine Ratio (calculated), Calcium, Carbon Dioxide, Chloride, Creatinine with GFR Estimated, Globulin (calculated), Glucose, Potassium, Sodium, Total Bilirubin, Total Protein, Urea Nitrogen Vitamin D,1,25 (OH)2,Total; Vitamin D3, 1,25 (OH)2; Vitamin D2, 1,25 (OH)2 Lactic Acid Dehydrogenase (LD)(LDH), serum
Patient Instructions:
You should fast for 12 hours before collection of the specimen. Fasting is defined as no consumption of food or beverage other than water for at least 12 hours before testing. Estimated turnaround for results is 5 business days. If confirmation testing is required, the estimated time may be extended.
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Price:
$156
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Norepinephrine, Plasma
*Build Your Own Panel Eligible [?]
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$406
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Description:
Plasma norepinephrine is an independent risk factor in patients with chronic congestive heart failure that relates to subsequent mortality. Norepinephrine is useful in evaluating patients with hypertension.
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Price:
$406
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Norovirus RNA, Qualitative Real-Time PCR
*Build Your Own Panel Eligible [?]
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$679
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Description:
Reverse Transcription PCR (RT-PCR) assays are widely used for the rapid and sensitive detection of noroviruses in biological specimens.
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Price:
$679
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Nortriptyline
*Build Your Own Panel Eligible [?]
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$269
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Description:
Nortriptyline is a tricyclic antidepressant. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and to avoid toxicity.
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Price:
$269
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NOTCH3 (CADASIL) Sequencing Test
*Build Your Own Panel Eligible [?]
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$4712
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Description:
Detects sequence variants in the NOTCH3 gene in patients with CADASIL (Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy).
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Price:
$4712
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NPM1 Mutation for MRD, Quantitative PCR
*Build Your Own Panel Eligible [?]
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$917
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Description:
NPM1, encoding the nucleophosmin protein, is mutated in about 30% of the AML patients and the mutations are predominantly a 4-base insertion which causes a frameshift of the NPM1 protein to amino acid sequence 288 near the C-terminus. NPM1, Quantitative for MRD is an allele-specific qPCR assay designed to quantitatively detect the presence of the NPM1 mutation found previously as a way to assess the minimal/measurable residual disease (MRD) status after initial induction therapy for prognosis of disease progression and consideration of consolidation treatment selection.
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Price:
$917
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NPM (Exon 12) Mutation Analysis, Cell-based
*Build Your Own Panel Eligible [?]
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$701
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Description:
Acute Myeloid Leukemia (AML) is a clinically heterogeneous disease. Recurrent cytogenetic abnormalities help define subgroups with different prognosis and identify patients whom might benefit from targeted therapies. However, almost half adults AML cases display a normal karyotype by conventional cytogenetics, and the clinical and molecular features of this large subgroup of patients are poorly understood. The NPM exon 12 mutation can serve as predictor in AML cases with a normal karyotype, good response to induction chemotherapy and as a marker for monitoring of minimal residual disease. NPM exon 12 mutations are AML-specific since they are not detected in normal cells or other neoplasms.
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Price:
$701
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NRAS Mutation Analysis
*Build Your Own Panel Eligible [?]
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$852
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Description:
NRAS mutations have been described in a variety of cancers including 3-5% of colorectal carcinomas, 10-20% of melanomas and 10% of acute myeloid leukemias. Mutations leading to an amino acid substitution at positions 12, 13, 61 and 146 of NRAS are the most common in naturally occurring neoplasms.
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Price:
$852
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N-Telopeptide, Serum
*Build Your Own Panel Eligible [?]
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$358
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Description:
Serum N-Telopeptide (NTx) levels may be used in predicting skeletal response (bone mineral density) to antiresorptive therapy and in monitoring bone resorption changes following initiation of antiresorptive therapy. Prior to initiating antiresorptive therapy, a serum NTx level is used to determine the probability for a decrease in bone mineral density (BMD) after one year in postmenopausal women treated with hormonal antiresorptive therapy relative to those treated with calcium supplementation.
Significant deviations from the normal range may require further evaluation by your physician.
Includes:
N-Telopeptide, Serum
Alternative Name(s):
NTX, Serum
Estimated turnaround for results is 7 business days.
Categories:
Hormones & metabolism,
Price:
$358
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NT-proBNP
*Build Your Own Panel Eligible [?]
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$287
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Description:
- Checks heart strain or stress levels.
- Assesses heart failure risk.
- Evaluates heart health conditions.
Includes:
NT-proBNP
Categories:
Price:
$287
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NT-Pro BNP
*Build Your Own Panel Eligible [?]
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$243
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Categories:
Price:
$243
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NTRK FusionSEQ Panel
*Build Your Own Panel Eligible [?]
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$945
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Description:
The NTRK FusionSEQ assay will detect the presence of gene rearrangements (fusions) in NTRK1, NTRK2 and NTRK3. FDA- approved therapies and clinical trials are available for patients with these genomic abnormalities in certain solid tumors, and the detection of these abnormalities is beneficial in the management of disease and survival of the patient.
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Price:
$945
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Nutmeg (f282) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This test detects the presence of specific IgE against nutmeg. A positive test only indicates that a person is sensitized and potentially allergic to this allergen. A diagnosis of allergy requires clinical signs and symptoms that appear to be associated with exposure to the allergen in addition to the detection of markers of IgE sensitization [1].More specific information about this allergen can be found on the following website: https://www.thermofisher.com/phadia/us/en/resources/allergen-encyclopedia.htmlReference1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.
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Price:
$49
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Nutrition Balance Scan
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$492
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Description:
Our blood test for nutrition is a comprehensive tool designed to assess the nutrient status of your body. This panel analyzes key mineral, vitamin and nutrition levels to identify any deficiencies that may be affecting your health and well-being. Vitamin deficiencies are a common health concern and can occur due to a variety of factors, such as poor dietary choices, underlying health conditions, medications, and even genetic factors. Nutrition blood tests are essential for maintaining overall health and preventing the development of chronic diseases. Our blood tests for nutrition are an excellent resource for anyone looking to gain insight into their nutritional status. Whether you are looking to address specific health concerns or simply want to ensure that you are getting the nutrients your body needs, these nutrition panels can allow you to take proactive steps toward achieving optimal health and wellness.
Includes:
Vitamin A (Retinol) Vitamin B12 Folate (Folic Acid) Vitamin C Alternative Name(s): Ascorbic Acid Vitamin D, 25-OH, Total Vitamin K Complete Blood Count / CBC (includes Differential and Platelets): WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet Count, MPV and Differential (Absolute and Percent - Neutrophils, Lymphocytes, Monocytes, Eosinophils, and Basophils) Comprehensive Metabolic Profile ( includes eGFR ): Albumin, Albumin/Globulin Ratio (calculated), Alkaline Phosphatase, ALT, AST, BUN/Creatinine Ratio (calculated), Calcium, Carbon Dioxide, Chloride, Creatinine with GFR Estimated, Globulin (calculated), Glucose, Potassium, Sodium, Total Bilirubin, Total Protein, Urea Nitrogen Ferritin, serum Iron, serum
Patient Instructions:
You should fast for 12 hours before collection of the specimen. Fasting is defined as no consumption of food or beverage other than water for at least 12 hours before testing. Specimens should be collected in the morning since iron values decrease by 30% during the course of the day and there can be significant interference from lipemia. Some tests in this panel may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H or coenzyme R). Refrain from eating fruits and from taking vitamin C supplements for 24 hours prior to collection. Patient should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample. Folate assays of samples from patients receiving therapy with certain pharmaceuticals (eg, methotrexate or leucovorin), are contraindicated because of the cross-reactivity of folate binding protein with these compounds. In patients receiving therapy with high biotin doses (ie, > 5 mg/day), no sample should be taken until at least eight hours after the last biotin administration. Patient should refrain from eating liver and taking multivitamins or vitamin K at least 24 hours before sample collection. Estimated turnaround for results is 7 business days. If confirmation testing is required, the estimated time may be extended.
Categories:
Fitness, nutrition, anti-aging,
Price:
$492
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Oak (t7) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This test quantifies an individual’s IgE response to oak. It is an in vitro quantitative assay, which is intended to be used in conjunction with other clinical information to aid in the diagnosis of allergic diseases [1]. While allergen-specific serum IgE testing is considered comparable to skin testing in many instances, both the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology recognize that allergen-specific serum IgE testing may be preferred in some clinical situations. These include 1) the presence of widespread skin disease, 2) the recent use of antihistamines or other medications that can affect the results of allergy skin tests, 3) uncooperative patients, and 4) medical history suggesting that allergen skin testing would pose a significant risk for a serious allergic reaction [1]. A definitive clinical diagnosis of allergy should not be based on the results of any single diagnostic method, but should be made by a trained healthcare professional after all clinical and laboratory findings have been evaluated. More specific information about this allergen can be found at http://www.phadia.com/en/Products/Allergy-testing-products/ImmunoCAP-Allergen-Information/Tree-Pollens/Allergens/Oak/ Reference 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(suppl 3):S1-S148.
Categories:
Price:
$49
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Oak, White IgG4
*Build Your Own Panel Eligible [?]
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$254
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Description:
- Identify oak pollen allergy triggers
- Screen seasonal sneezing and congestion causes
- Track immune reactions to tree allergens
Categories:
Price:
$254
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Oat (f7) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This test quantifies an individual’s IgE response to oats. It is an in vitro quantitative assay, which is intended to be used in conjunction with other clinical information to aid in the diagnosis of food allergy [1]. While allergen-specific serum IgE testing is considered comparable to skin testing in many instances, both the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology recognize that allergen-specific serum IgE testing may be preferred in some clinical situations. These include 1) the presence of widespread skin disease, 2) the recent use of antihistamines or other medications that can affect the results of allergy skin tests, 3) uncooperative patients, and 4) medical history suggesting that allergen skin testing would pose a significant risk for a serious allergic reaction [1]. Food-specific IgE tests are extremely sensitive. However, a positive test result only indicates that a patient is IgE sensitized to the food of concern. Many IgE-sensitized patients do not develop any symptoms when this food is ingested. A diagnosis of food allergy should only be made by a trained medical provider, after conducting a thorough clinical evaluation [2,3]. While food-specific IgE test results may contribute to that evaluation, they cannot replace it. In this regard, detection of food-specific IgE in serum provides evidence of IgE sensitization, but a history of clinical reactivity to the food of concern, is required to make a diagnosis of IgE-mediated food allergy. Moreover, several forms of food hypersensitivity are not associated with the presence of food-specific IgE in serum. More specific information about this allergen can be found at http://www.phadia.com/en/products/allergy-testing-products/immunocap-allergen-information/food-of-plant-origin/grains/oat/ References 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(suppl 3):S1-S148. 2. Sampson HA, et al. J Allergy Clin Immunol. 2014;134(5):1016-1025. 3. Boyce JA, et al. J Allergy Clin Immunol. 2010;126(6 suppl):S1-S58.
Categories:
Price:
$49
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Obstetric Panel
*Build Your Own Panel Eligible [?]
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$168
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Description:
This panel includes tests used for routine prenatal care during early pregnancy, which have been recommended for all women during early pregnancy by the American College of Obstetricians and Gynecologists (ACOG) [1]. An alternative panel, the Obstetric Panel with Fourth Generation HIV (test code 93802), is available and may be ordered to simultaneously screen for HIV infection.Additional tests typically done in early pregnancy (but not included in this panel) include urinalysis, tests for sexually transmitted infections and tuberculosis, and blood glucose testing for women at high risk for gestational diabetes.The CBC with differential evaluates the levels and types of red blood cells, white blood cells, and platelets in the patient's blood. This information can help identify conditions such as anemia, low platelet count, and other blood cell disorders [1].The blood type, including ABO and Rh status, as well as the antibody screen, will provide information about a women's current and/or future risk for hemolytic disease of the fetus and newborn. These tests may also be useful to define any special transfusion requirements [1].Syphilis, when transmitted from mother to fetus, may cause birth defects and neonatal death [2]. Syphilis testing is performed using a combination of assays. The RPR is performed initially. If the result is reactive, a titer and a confirmatory test (fluorescent treponemal antibody absorption assay; FTA-ABS) will be performed at additional cost.Hepatitis B, a disease that affects the liver, can be passed from mother to fetus [1]. Hepatitis B screening is performed with the hepatitis B surface antigen test. If positive, additional confirmatory testing based on the test manufacturer's FDA-approved recommendations will be performed at additional cost.Rubella, or German measles, can cause birth defects if transmitted from mother to baby during pregnancy. Testing of the mother's immune status against rubella will indicate if the mother and baby are protected from infection by the virus during this time. Vaccination for rubella during pregnancy is not recommended [1].Note: Test results should be interpreted in the context of pertinent clinical and family history and physical examination findings.References1. American College of Obstetricians and Gynecologists. Published November 2019. Accessed December 15, 2019. https://www.acog.org/Patients/FAQs/Routine-Tests-During-Pregnancy?IsMobileSet=false2. Koumans EH, et al. Am J Obstet Gynecol. 2012;206:158.e1-158.e11.
Categories:
Price:
$168
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Obstetric Panel with Fourth Generation HIV
*Build Your Own Panel Eligible [?]
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$223
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Description:
This Obstetric Panel would be appropriate in obstetric patients that are at risk for HIV.
Categories:
Price:
$223
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Obstetric Panel with Fourth Generation HIV,Hepatitis C Antibody with Reflex
*Build Your Own Panel Eligible [?]
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$261
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Description:
This panel includes tests used for routine prenatal care during early pregnancy, including HIV-1/2 Antigen and Antibodies, Fourth Generation, with Reflexes and Hepatitis C Antibody with Reflex to HCV, RNA, Quantitative, Real-Time PCR, which have been recommended for all women during early pregnancy by the American College of Obstetricians and Gynecologists (ACOG) [1, 3]. Alternative Panels are: Obstetric Panel (test code 20210), Obstetric Panel with Fourth Generation HIV (test code 93802).Additional tests typically done in early pregnancy (but not included in this panel) include urinalysis, tests for sexually transmitted infections and tuberculosis, and blood glucose testing for women at high risk for gestational diabetes.The CBC with differential evaluates the levels and types of red blood cells, white blood cells, and platelets in the patient's blood. This information can help identify conditions such as anemia, low platelet count, and other blood cell disorders [1].The blood type, including ABO and Rh status, as well as the antibody screen, will provide information about a woman's current and/or future risk for hemolytic disease of the fetus and newborn. These tests may also be useful to define any special transfusion requirements [1].Syphilis, when transmitted from mother to fetus, may cause birth defects and neonatal death [2]. Syphilis testing is performed using a combination of assays. The RPR is performed initially. If the result is reactive, a titer and a confirmatory test (fluorescent treponemal antibody absorption assay; FTA-ABS) will be performed at additional cost.Hepatitis B, a disease that affects the liver, can be passed from mother to fetus [1]. Hepatitis B screening is performed with the hepatitis B surface antigen test. If positive, additional confirmatory testing based on the test manufacturer's FDA-approved recommendations will be performed at additional cost.Rubella, or German measles, can cause birth defects if transmitted from mother to baby during pregnancy. Testing of the mother's immune status against rubella will indicate if the mother and baby are protected from infection by the virus during this time. Vaccination for rubella during pregnancy is not recommended [1].Hepatitis C (HCV) screening is recommended by the American College of Obstetricians and Gynecologists for all pregnant individuals during each pregnancy. HCV screening during the first prenatal blood assessment obtained in every pregnancy is recommended to identify pregnant individuals with HCV infection and infants who should receive testing at a pediatric visit [3]. For the pregnant person, diagnosing HCV infection in early pregnancy gives providers the opportunity to reduce the risk of HCV vertical transmission with preferential performance of amniocentesis over chorionic villus sampling when needed, and avoidance of prolonged rupture of membranes, episiotomy, and fetal scalp monitoring when possible. Furthermore, children born to mothers with diagnosed HCV infection can be tested as early as 2 months of age and monitored for treatment needs to prevent progression to cirrhosis. Finally, persons diagnosed with HCV during pregnancy can receive treatment for hepatitis C, postnatally, to prevent progression to cirrhosis, liver failure, and death as well as reduce the risk of HCV transmission. [4,5]Note: Test results should be interpreted in the context of pertinent clinical and family history and physical examination findings.References1. American College of Obstetricians and Gynecologists. Updated July 2021. Accessed June 14, 2022. https://www.acog.org/Patients/FAQs/Routine-Tests-During-Pregnancy2. Koumans EH, et al. Am J Obstet Gynecol. 2012;206:158.e1-158.e11.3. Routine Hepatitis C Virus Screening in Pregnant Individuals Practice Advisory, May 2021 This Practice Advisory was developed by the American College of Obstetricians and Gynecologists (ACOG) in collaboration with Hughes BL, Jamieson DJ, Kaimal AJ, Caughey AB, Eke A, McReynolds M https://opqic.org/acog-practice-advisory-routine-hepatitis-c-virus-screening-in-pregnant-individuals/4. Schillie SF, Canary L, Koneru A, et al. Hepatitis C virus in women of childbearing age, pregnant women, and children. Am J Prev Med 2018;55:633-41.5. Andes A, Ellenberg k, Vakos A, Collins J and Fryer K. Hepatitis C Virus in Pregnancy: A Systematic Review of the Literature. Am J Perinatol. 2020 38(S 01):e1-e13. doi: 10.1055/s-0040-1709672.
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Price:
$261
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OCT 3/4, IHC with Interpretation
*Build Your Own Panel Eligible [?]
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$442
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Description:
Expressed in stem cells, useful in identifying germ cell tumors including seminoma, dysgerminoma and embryonal carcinoma.
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Price:
$442
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OCT 3/4, IHC without Interpretation
*Build Your Own Panel Eligible [?]
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$370
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Description:
Expressed in stem cells, useful in identifying germ cell tumors including seminoma, dysgerminoma and embryonal carcinoma.
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Price:
$370
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Octopus (f59) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This test detects the presence of specific IgE against octopus. A positive test only indicates that a person is sensitized and potentially allergic to this allergen. A diagnosis of allergy requires clinical signs and symptoms that appear to be associated with exposure to the allergen in addition to the detection of markers of IgE sensitization [1].More specific information about this allergen can be found on the following website: https://www.thermofisher.com/phadia/us/en/resources/allergen-encyclopedia.htmlReference1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.
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Price:
$49
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Olanzapine
*Build Your Own Panel Eligible [?]
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$656
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Description:
Therapeutic drug monitoring of antipsychotic drug.
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Price:
$656
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Olive Tree (t9) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This test quantifies an individual's IgE response to olive tree. Allergen-specific serum IgE testing is considered comparable to skin testing and may be preferred in some clinical situations. However, a positive test result only indicates that a patient is sensitized to the allergen of concern. Many IgE-sensitized individuals do not develop any symptoms when exposed to the allergen. A diagnosis of allergy should only be made by a trained medical provider after conducting a thorough clinical evaluation [1].More specific information about this allergen can be found on the following website: https://www.thermofisher.com/phadia/us/en/resources/allergen-encyclopedia.htmlReference 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.
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Price:
$49
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Omega 3 and Omega 6 Fatty Acids
*Build Your Own Panel Eligible [?]
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$181
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Description:
This test is used to determine fatty acid-associated risk for cardiovascular events, screen for omega-3 fatty acid deficiency, and monitor omega-3 fatty acid intake.
Includes:
Alternative Name(s): Omega 3 and 6 Fatty Acids
Patient Instructions:
Patient should fast overnight.
Estimated turnaround for results is 10 business days. If confirmation testing is required, the estimated time may be extended.
Categories:
General wellness,
Heart & cholesterol,
Price:
$181
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Onion (f48) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This test detects the presence of specific IgE against onions. A positive test only indicates that a person is sensitized and potentially allergic to this allergen. A diagnosis of allergy requires clinical signs and symptoms that appear to be associated with exposure to the allergen in addition to the detection of markers of IgE sensitization [1].More specific information about this allergen can be found on the following website: https://www.thermofisher.com/phadia/us/en/resources/allergen-encyclopedia.htmlReference1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.
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Price:
$49
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Opiate, Confirmation, Meconium
*Build Your Own Panel Eligible [?]
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$326
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Description:
This definitive drug assay is used to confirm in utero opioid exposure and identify the specific opioid(s) with gas chromatography/mass spectrometry [1]. Opioids included in this panel are codeine, morphine, hydrocodone, hydromorphone, and oxycodone. This test does not detect fentanyl, a major contributor to fatal overdoses in the United States [2].Meconium begins to form around 12 weeks' gestation and accumulates mostly during the last trimester. Opioids used by mothers, and opioid metabolites, may deposit in meconium by diffusing across placentas or fetuses swallowing amniotic fluid. Adverse effects of in utero opioid exposure include preterm birth, low birthweight, birth defects, and neonatal opioid withdrawal syndrome. The clinical presentation of neonates varies by opioid type, maternal drug history, and other factors. Maternal self-reporting of opioid intake may be unreliable. Therefore, confirming opioid exposure via meconium testing can provide information necessary for clinical management of affected neonates [1,3,4].The American Academy of Pediatrics recommends that meconium, urine, and umbilical cord tissue should all be considered for opioid testing. However, neonatal urine reflects only recent opioid exposure; umbilical cord tissue, though easy to collect, is not well understood as a specimen for opioid testing. For mothers who receive frequent toxicology testing to monitor treatment of opioid use disorder, meconium or umbilical cord tissue opioid testing does not provide additional clinical information and may not be necessary [4].Results equal to or greater than the cutoff value for each opioid are reported as quantitative values and indicate in utero exposure; results less than cutoff are reported as negative. Because the frequency of drug use during pregnancy may affect detection of drugs in meconium, negative results do rule out in utero exposure to opioids [1].The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.References1. Langman LJ, et al, eds. Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients. American Association for Clinical Chemistry; 2018. Accessed October 1, 2021. https://www.aacc.org/-/media/Files/Science-and-Practice/Practice-Guidelines/Pain-Management/LMPGPain-Management20171220.pdf?la=en&hash=19670524407619F78999AB60731A24CB4901939D2. Wilson N, et al. MMWR Morb Mortal Wkly Rep. 2020;69(11):290-297.3. About opioid use during pregnancy. Centers for Disease Control and Prevention. Accessed November 2, 2021. https://www.cdc.gov/pregnancy/opioids/basics.html4. Patrick SW, et al; Committee on Fetus and Newborn; Committee on Substance Use and Prevention. Pediatrics. 2020;146(5).
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Price:
$326
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