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Anemia Panel: 18 Tests

What is an anemia panel and what does it test for?

An anemia panel is a series of blood tests that evaluate the components of your blood, such as hemoglobin, hematocrit, and red blood cell count. It helps diagnose anemia by identifying deficiencies in iron, vitamin B12, or folate, along with conditions like sickle cell anemia or thalassemia.

This 18 test anemia panel includes all tests needed to diagnose the degree and cause of anemia, including a CBC panel (red blood cells, hemoglobin, etc), Ferritin, Iron, Total Iron Binding Capacity, Folate, and Vitamin B-12

This 18 test anemia panel includes all tests needed to diagnose the degree and cause of anemia, including a CBC panel (red blood cells, hemoglobin, etc), Ferritin, Iron, Total Iron Binding Capacity, Folate, and Vitamin B-12.

This lab test panel is ideal for people who feel fatigued and who may suspect anemia or low iron levels. Exploring the biomakers in this panel will be beneficial for people who have a menstrual cycle that involves a lot of blood loss, those who might have vitamin deficiencies, and those who suspect internal bleeding. Also, men and women who donate blood frequently may find this panel useful to ensure that they have not depleted their iron, ferritin and other markers of iron stores that can dramatically impact their energy level, mental function, mood, and quality of life. The results of this panel, including anemia and low iron test results, can provide valuable information about a person's health and aid in diagnosing and treating anemia.

Anemia is a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood, or a lowered ability of the blood to carry oxygen. It can have several causes.

Symptoms of Anemia

When anemia comes on slowly, the symptoms are often vague and may include feeling tired, weakness, shortness of breath, and a poor ability to exercise. When the anemia comes on quickly, symptoms may include confusion, feeling like one is going to pass out, loss of consciousness, and increased thirst. Anemia must be significant before a person becomes noticeably pale. It is important to discuss any signs and symptoms of anemia, including an increased risk of anemia, with your healthcare provider, especially if you have risk factors such as a family history or certain medical conditions.

Causes of Anemia:

Blood loss, a decrease in red blood cell production, and an increase in red blood cell breakdown are all potential causes of anemia. Causes of blood loss include trauma and gastrointestinal bleeding.

Causes of decreased production include iron deficiency, vitamin B12 deficiency, thalassemia, and a number of neoplasms of the bone marrow. Causes of increased breakdown include genetic conditions such as sickle cell anemia, infections such as malaria, and certain autoimmune diseases.

Types of Anemia:

Anemia can also be classified based on the size of the red blood cells and amount of hemoglobin in each cell. If the cells are small, it is called microcytic anemia; if they are large, it is called macrocytic anemia; and if they are normal sized, it is called normocytic anemia. Anemia of chronic disease, a type of normocytic anemia, is commonly seen in regions with endemic malaria/protozoal illness and in impoverished areas where there is a higher risk of nutritional anemia. Aplastic anemia, a rare condition where bone marrow no longer produces red blood cells, can also be diagnosed through a comprehensive metabolic panel (CMP) test.

Diagnosis of Anemia:

The diagnosis of anemia in men is based on a hemoglobin of less than 130 to 140 g/L (13 to 14 g/dL); in women, it is less than 120 to 130 g/L (12 to 13 g/dL).

Anemia Panel Tests Included:

CBC (Complete Blood Count) Panel:

Complete Blood Count

Whole blood is made up of various types of cells suspended in a liquid called plasma. The complete blood count (CBC) is an inventory of the different cellular components of the blood: red blood cells, white blood cells, and platelets. Blood cell counts are typically reported as the number of cells in a cubic millimeter of blood (cells/mm3) or as a percentage of all blood cells. This test is performed by analyzing a blood sample, which includes measuring platelet count, mean platelet volume, and the average size of red blood cells, to provide a comprehensive understanding of an individual's blood health.

 Red Blood Cells

Red blood cells (erythrocytes) carry oxygen from the lungs to the body's cells, bound to a molecule called hemoglobin. Anemia is a condition characterized by a reduction in the number of red blood cells, often leaving a person fatigued, weak, and short of breath. Several tests are used to help diagnose various types of anemia, including those associated with bone marrow disease. Treatment for these anemias may include blood transfusions, hormone therapy, or bone marrow transplants, depending on the specific form of anemia.

 Red Blood Cell Count (RBC): the total number of red blood cells in a quantity of blood. Normal ranges are 4.5–6.0 million cells/mm3 for men and 4.0–5.5 million cells/mm3 for women. (Women typically have lower counts than men due to the loss of blood through menstruation.)

 Hematocrit (HCT): the proportion of red blood cells as a percentage of total blood volume. A normal hematocrit is 40–55% for men and 35–45% for women.

 Hemoglobin (HGB): the number of grams of hemoglobin in a deciliter of blood (g/dL). Normal levels in healthy adults are 14–18 g/dL for men and 12–16 g/dL for women. As a rough guideline, hemoglobin should be about one-third the hematocrit.

 Mean Corpuscular Hemoglobin (MCH) and MCH Concentration (MCHC): the amount or concentration, respectively, of hemoglobin in an average red blood cell.

 Mean Corpuscular Volume (MCV): the average size, or volume, of individual red blood cells. Conditions such as iron deficiency can lead to smaller than normal red blood cells, while certain vitamin deficiencies and some drugs can produce larger than normal cells.

 Red Blood Cell Distribution Width (RDW): a measure of the size and uniformity of red blood cells.

 White Blood Cells

White blood cells (leukocytes) carry out the body's immune responses. The CBC looks at numbers of various different types of white blood cells.

 White Blood Cell Count (WBC): the total number of white blood cells in a quantity of blood. A healthy adult normally has 4,000–11,000 white blood cells/mm3. A WBC increase often indicates that a person is actively fighting an infection or has recently received a vaccine. Decreased WBC (leukopenia) can leave a person vulnerable to various pathogens and cancers.

 Differential: a report of the proportions of different types of white blood cells as a percentage of the total number of white cells; these percentages may be multiplied by the WBC to obtain absolute counts.

 Neutrophils: a type of cell that fights bacterial infections. Neutrophils normally make up about 50–70% of all white blood cells. The risk of bacterial infection increases when the absolute neutrophil count falls below about 500–750 cells/mm3.

 Lymphocytes: there are two main types of lymphocytes. B cells produce antibodies that fight foreign invaders in the body, while T cells target infected or cancerous cells and help coordinate the overall immune response. A normal lymphocyte count is about 20–40% of all white blood cells.

 Monocytes: a type of cell that fights pathogens by engulfing and destroying them. Monocytes circulate in the blood for about 24 hours; when they leave the bloodstream and migrate into the tissues, they mature into macrophages. Monocytes and macrophages normally account for 2-10% of all white blood cells.

 Eosinophils: cells that play a role in defense against parasites and in allergic reactions. They normally make up 0-6% of all white blood cells.

 Basophils: another type of cell involved in allergic reactions, in particular the release of histamine. They normally account for 1% or less of all white blood cells.

Platelets

 Platelets (thrombocytes) are necessary for blood clotting. A normal platelet count is about 130,000–440,000 cells/mm3. Low platelet counts (thrombocytopenia), which can cause easy bruising and excessive bleeding, may be a result of some medications, autoimmune reactions, spleen-accelerated destruction, or specific immune diseases.

Folic Acid:

B12 and folic acid blood testing help doctors diagnose central nervous system disorders, anemia, and malabsorption syndromes. B12 and folic acid also play an important role in energy level, muscle strength and memory. Because B12 and folate are derived solely from dietary intake, such as egg yolks, beef, poultry and fish, many people are deficient in these important vitamins.

Vitamin B-12 Level:

Vitamin B-12 is an essential vitamin. Low blood levels of B12 can cause: Anemia and pernicious anemia, loss of balance , numbness or tingling in the arms and legs, and weakness

Iron & TIBC:

The serum iron test measures the amount of iron in your blood. The total iron-binding capacity (TIBC) test looks at how well iron moves through your body. Iron is an important mineral that your body needs to stay healthy. Your body uses iron to make hemoglobin, the protein in your red blood cells that carries oxygen throughout your body. If you don't have enough iron, you may not have enough hemoglobin. This condition is called iron deficiency anemia, one of the different types of anemia. Transferrin, a protein that your liver produces, is primarily responsible for carrying or binding iron in your body. The TIBC test is based on certain proteins, including transferrin, found in the blood. Your transferrin levels are almost always measured along with iron and TIBC. Additionally, the ferritin test can help determine how much iron your body is storing, providing a more comprehensive understanding of your iron levels.

Ferritin:

Ferritin is a protein found in the bloodstream which stores iron. Ferritin helps transport iron where it's most needed in the body. Too much or too little ferritin can cause a lot of health issues and that's why you should check it often. The levels of ferritin in the body are different for men and women. For example: men: 24–500 ng/ml of blood; women: 22–200 ng/ml of blood. However, many people may have anemia symptoms at the lower end of the "normal" range.

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Frequently Asked Questions About the Anemia Panel:

Can dietary changes affect the results of an anemia panel?

Dietary changes can indeed affect the results of an anemia panel. Nutritional deficiencies are one of many causes of anemia, a condition that manifests as a lack of healthy red blood cells or hemoglobin in the blood. For example, iron-deficiency anemia is a common type of anemia that can result from insufficient dietary intake of iron.

Making dietary changes to include more iron-rich foods, such as red meat, poultry, beans, lentils, and leafy green vegetables, can help improve iron levels in the body and potentially impact the results of an anemia panel. On the other hand, certain dietary factors, like consuming excessive amounts of tea or coffee with meals, can inhibit iron absorption and influence test results.

It's important to consult with a healthcare provider or a nutritionist before making significant dietary changes if you suspect you have anemia or are undergoing an anemia panel test to ensure that your diet modifications align with your overall health goals and medical needs.

Are there any specific preparations needed before getting an anemia panel done?

Before getting an anemia panel done, it is advisable to follow these specific preparations:

1. Fasting: In some cases, fasting may be required before the test. Your healthcare provider will inform you if fasting is necessary for your test.

2. Medication: Inform your healthcare provider about any medications or supplements you are currently taking, as certain medications can affect the results of the test.

3. Timing: Your healthcare provider may recommend a specific time for the test, so be sure to follow that timeframe.

4. Hydration: Drinking plenty of water before the test can help make it easier to draw blood for the panel.

5. Clothing: Wear clothing that allows easy access to your arm for blood collection.

Following these preparations can help ensure accurate results from your anemia panel test.

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Price: $144

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Discounted Labs offers a basic test for adrenal insufficiency. This test measures cortisol, ACTH, and DHEA levels. This is the first step in the process. After looking at these results, doctors might suggest an ACTH stimulation test. They may also check the levels of renin, potassium, and sodium. A CT scan of the adrenal glands can help find any growths. To look for Addison's Disease, which is a type of primary adrenal insufficiency, tests for 21-hydroxylase should also be done.

What is Adrenal Insufficiency and What are the Symptoms?

Adrenal insufficiency (AI) happens when the adrenal glands do not make enough steroid hormones. The main hormone that is low is cortisol. There may also be low amounts of aldosterone. Aldosterone is important for managing sodium and potassium levels in the body. It helps the body hold onto water, too. Many people with this condition feel a strong desire for salt or salty foods. This is because they lose sodium through urine.

Addison's disease and congenital adrenal hyperplasia are types of adrenal insufficiency. If this condition is not treated, it can lead to several health problems. These problems can include stomach pain, vomiting, muscle weakness, and feeling very tired. A person may feel down, have low blood pressure, lose weight, suffer from kidney failure, or notice changes in their mood. In severe cases, it can lead to shock, known as an adrenal crisis.

Adrenal insufficiency was really dangerous before 1949. In that year, cortisone was invented. This was a big step forward because it allowed us to replace glucocorticoids in treatment. Still, even with this major development, diagnosing and treating people with adrenal insufficiency remains tough.

Adrenal Insufficiency (AI) Caused by Medications

A study at the University of Bologna looked at more than 8,000 cases of AI. The aim was to find out the main reasons for drug-related AI and how this has changed over the last twenty years. The researchers discovered that 97.5% of the cases were serious. Furthermore, 41.1% of these cases needed hospital treatment.

The number of AI cases has gone up in recent years. A lot of these cases are about steroids. The use of these drugs has increased too. In 2015, cases of monoclonal antibodies made up 33%. Many of the cases included non-steroidal anti-inflammatory drugs. Researchers discovered that more than 70% of people used steroids alongside them.

What Lab Tests Are Used to Initiate Diagnosis of Adrenal Insufficiency?

Discounted Labs offers a simple adrenal insufficiency panel. This panel measures cortisol, ACTH, and dhea levels. These tests are only the beginning. Depending on the results, doctors may suggest more tests. These can include an ACTH stimulation test, a renin test, a potassium test, an aldosterone test, and a CT scan of the adrenal glands. To find Addison's disease, which is a type of primary adrenal insufficiency, labs will check for 21-hydroxylase autoantibodies.

Cortisol Blood Test

What is Cortisol?

Cortisol, also known as hydrocortisone, is an important type of glucocorticosteroid. It has several key roles in our body. Like other glucocorticosteroids, cortisol is made from cholesterol. This process takes place in a part of the adrenal gland called the zona fasciculata.

When cortisol enters the blood, about 90% attaches to proteins known as corticosteroid-binding globulin (CBG) and albumin. A tiny amount of cortisol remains free in the blood. This free cortisol can then bind to its receptors.

Functions of Cortisol

Cortisol has several important effects on the body. First, it raises blood sugar levels. This happens because cortisol helps create glucose and breaks down substances in the body. Additionally, cortisol can lower inflammation but may also weaken the immune system.

Production of Cortisol in the Body

The adrenal gland makes and releases cortisol. This happens through a system called the hypothalamus-pituitary-adrenal cortex-axis. When cortisol levels drop, the hypothalamus releases a hormone known as corticotropin-releasing hormone (CRH). This hormone tells the pituitary gland to release adrenocorticotropic hormone (ACTH). Then, ACTH prompts the adrenal gland to produce and release more cortisol. Cortisol also signals the pituitary gland and hypothalamus to lower cortisol production. When a person is under stress, their body produces more cortisol.

Cortisol Blood Levels During the Day

Serum cortisol levels change throughout the day. They reach their highest point in the morning. As the day goes on, cortisol levels decrease. By evening, they are about half of what they were in the morning. To correctly read the results, you need to know when the serum sample was collected.

What the Cortisol Test Can Help to Diagnose

The cortisol level in a patient helps doctors learn about the health of the adrenal gland, pituitary, and hypothalamus. High cortisol levels can show problems like Cushing syndrome. Low levels may suggest Addison disease. Checking these levels is important for treatment. Doctors might use dexamethasone suppression therapy for Cushing syndrome or hormone replacement therapy for Addison disease.

Factors that Affect Cortisol Blood Levels

Pregnancy, birth control, and estrogen therapy can increase cortisol levels. If patients take medications such as prednisolone, methylprednisolone, or prednisone, their cortisol levels might show higher numbers than what they actually are. Tests using metyrapone can show higher levels of 11-deoxycortisol. Occasionally, cortisol levels might appear high because of cross-reactions. Patients with 21-hydroxylase deficiency may have more 21-deoxycortisol. This can cause them to have higher cortisol levels.

It is important to consider the time when you take a sample. This can affect the results. Cortisol levels follow a daily pattern. When a person experiences strong stress, cortisol levels can increase too.

Samples from patients who got monoclonal mouse antibodies can give wrong results. This can happen in tests and diagnoses. Sometimes, if there are very high levels of antibodies to streptavidin and ruthenium, this may affect the test results. However, the test includes several extras to help reduce these issues.

The best way to find out if someone has Cushing syndrome is by checking cortisol in a 24-hour urine sample. This method is effective because the amount of cortisol in urine does not follow the usual daily pattern of release.

Potential Interference for the Cortisol Test

This test may have problems if the sample comes from someone who is using biotin supplements. Biotin is known as vitamin B7, B8, vitamin H, or coenzyme R. It is crucial to ask all patients if they take biotin supplements before the test. Patients need to stop using biotin at least 72 hours before they provide a sample.

ACTH Test

What is Adrenal Corticotropic Hormone (ACTH)?

Adrenocorticotropic hormone is produced in the front part of the pituitary gland in your brain.

The job of ACTH is to manage the levels of cortisol in the body. Cortisol is a stress hormone made by the adrenal glands. This hormone acts like an alarm system in our body. As the main stress hormone, cortisol supports different areas of the brain in handling fear, emotions, and motivation.

Cortisol is mainly known for helping the body handle stress. It starts the "fight-or-flight" response. However, cortisol is also key for several other functions in the body, such as:

• Keep a regular sleep and wake schedule.
• Boost your energy to manage stress and feel normal again.
• It affects how the body uses carbs, proteins, and fats.
• Reduce inflammation.
• Manage blood pressure.
• Increase blood sugar.

What Are the Symptoms of High or Low ACTH-Induced Cortisol?

High cortisol levels can lead to many issues. Some of these are high blood pressure, obesity, high blood sugar, and swelling. On the other hand, low cortisol levels may cause weight loss, tiredness, low blood pressure, and weak muscles.

What is the ACTH Test?

If you have signs of having too much or too little cortisol, your doctor may suggest an ACTH test. This test looks at the levels of ACTH and cortisol in your blood. The ACTH test helps your doctor see if there are any problems with your cortisol levels. Before giving you a definite answer, your doctor might also do a physical checkup.

DHEA Test

Dehydroepiandrosterone, known as DHEA, is a hormone made by the adrenal gland. The brain also makes some DHEA. This hormone plays a key role in creating androgens and estrogens, which are sex hormones for both men and women. Most of the DHEA in your body comes from the adrenal glands. Doctors can check for problems like adrenal cancer or hyperplasia by measuring DHEA-S in the blood. This checking also helps find some types of congenital adrenal hyperplasia.

People who have primary or central adrenal insufficiency often show low levels of serum DHEA-S. However, just having low DHEA-S does not mean that a person has this condition. If their serum DHEA-S level is normal for their age and sex, it almost confirms that they likely do not have adrenal insufficiency.

References

The Changing Face of Drug-induced Adrenal Insufficiency in the Food and Drug Administration Adverse Event Reporting System

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Price: $204

Description:

This blood donation panel includes tests for various blood components: Hematocrit, iron & total iron binding capacity (TIBC), and ferritin.

This panel is designed to determine if:

1- Your blood donation or therapeutic phlebotomy was effective in lowering your high hematocrit without negatively affecting ferritin or iron.

2- It is safe to do another blood donation or therapeutic phlebotomy depending on ferritin or iron levels.

What is Blood Donation?

Blood donation is the process of giving blood to help patients in need of transfusions. It involves collecting blood from a donor and separating it into its various components, such as red blood cells, plasma, and platelets. Blood donation is a safe and voluntary process that helps save lives and improve the health of patients undergoing surgery, receiving treatment for cancer or blood disorders, and experiencing traumatic injuries.

Benefits of Donating Blood

Donating blood has numerous benefits for both the donor and the recipient. For the donor, donating blood can help lower blood pressure, reduce the risk of heart disease, and improve overall cardiovascular health. Donating blood regularly can also help maintain healthy iron levels and improve blood flow. For the recipient, blood donation can help save lives, improve health outcomes, and enhance the quality of life.

The Process of Donating Blood

The process of donating blood typically involves the following steps:

1. Registration: The donor registers to donate blood and provides basic information, such as name, address, and medical history.

2. Screening: The donor undergoes a medical screening to ensure they are eligible to donate blood. This includes a blood test to check for infectious diseases and a review of medical history.

3. Blood Collection: The donor’s blood is collected through a sterile needle inserted into a vein in the arm. The blood is collected into a bag or container, and the process typically takes 10-15 minutes.

4. Separation: The collected blood is separated into its various components, such as red blood cells, plasma, and platelets.

5. Testing: The donated blood is tested for infectious diseases, such as HIV and hepatitis, and for blood type and Rh factor.

6. Storage: The donated blood is stored in a blood bank or transfusion center until it is needed for a patient.

Overall, blood donation is a safe and rewarding process that helps save lives and improve the health of patients in need.

What is Hematocrit and Red Blood Cells?

Hematocrit is the portion of blood made up of red blood cells.

High hematocrit occurs when there is an excessive production of red blood cells, which can thicken the blood and place additional strain on the heart and blood vessels. High hematocrit can cause the blood to become very viscous or “sticky,” making it harder for the heart to pump. High blood pressure, strokes, and heart attacks can occur.

Testosterone Replacement Therapy and High Hematocrit

The association between testosterone replacement therapy and high hematocrit has been reported for the past few years as this therapy has become more mainstream. In addition to increasing muscle and sex drive, testosterone can increase the body’s production of red blood cells. This hematopoietic (blood-building) effect could be a good thing for those with mild anemia.

Although all testosterone replacement products can increase the number of red blood cells, the study showed a higher incidence of higher hematocrit in those using intramuscular testosterone than topical administration (testosterone patch was the main option used – no gels). Smoking and sleep apnea have also been associated with polycythemia and may contribute to the effects of other risk factors like TRT.

It’s important to check patients’ hemoglobin and hematocrit blood levels while on testosterone replacement therapy. As we all know, hemoglobin is the substance that makes blood red and helps transport oxygen in the blood. Additionally, carbon dioxide plays a crucial role in the function of hemoglobin, as it is carried by red blood cells throughout the body. Hematocrit reflects the proportion of red cells to total blood volume. A hematocrit of over 52 percent should be evaluated. Decreasing testosterone dose or stopping it are options that may not be the best for assuring patients’ best quality of life, however. Switching from injectable to transdermal testosterone may decrease hematocrit, but in many cases not to the degree needed.

Different medical guideline groups that recommend monitoring for testosterone replacement therapy agree about measuring hematocrit at month 3 and then annually, with some also recommending measurements at month 6 after starting testosterone.

How to Lower Hematocrit with Blood Donations—Warning

Many patients on testosterone replacement who experience polycythemia do not want to stop the therapy due to fears of re-experiencing the depression, fatigue, and low sex drive they had before starting treatment. Lowering hematocrit through blood donation can also reduce the risk of serious complications such as blood clots and stroke. For those patients, blood donation or therapeutic phlebotomy may be the answer. Therapeutic phlebotomy is very similar to what happens when donating blood, but this procedure is prescribed by physicians as a way to bring down blood hematocrit and viscosity when blood centers refuse to accept a blood donor because of his high hematocrit.

When donating blood, usually a unit of blood is extracted from the body. For every unit of blood donated or extracted through therapeutic phlebotomy, there is a 2-3 point decrease in hematocrit. If your hematocrit is 56 and you want to bring him under 50, you would have to give 2 to 3 units of blood. However, taking this much blood out in one single blood donation/phlebotomy session may deplete ferritin and iron levels, which can cause extreme fatigue. So, be conservative and only give 1 unit max even if you have to go more frequently. But be aware that the Red Cross has stated that blood donations done more frequently than every 2.5 months run the risk of lowering your ferritin and iron too much (which can cause fatigue), so make sure that you get a ferritin test to determine if you should take an iron supplement after donating or to make sure that ferritin is not low before the next blood donation. It is estimated that one unit of blood extracted can lower ferritin by 30 points. Ferritin levels under 45 have been linked to fatigue and other symptoms.

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Price: $60

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Understanding Hashimoto's Disease: Key Blood Tests for Diagnosis

1. TSH (Thyroid Stimulating Hormone) Test The TSH test is crucial for diagnosing Hashimoto's disease. It gauges the level of TSH that the pituitary gland produces, which in turn stimulates the thyroid to produce T4 and T3 hormones. Elevated TSH levels can indicate hypothyroidism, commonly associated with Hashimoto's disease 1 2.

2. Thyroid Hormone Tests These tests measure the levels of free T3 (triiodothyronine) and free T4 (thyroxine) in the blood. A low level of free T4, along with an elevated TSH level, is a key indicator of Hashimoto's disease 1 2.

3. Thyroid Antibody Tests Most individuals with Hashimoto's disease have thyroid peroxidase (TPO) antibodies in their blood. Testing for these and other thyroid-related antibodies is a significant step in diagnosing the condition 1 3

4. Thyroglobulin Antibody Test This test screens for antibodies against thyroglobulin, a protein in the thyroid gland. High levels are another marker of Hashimoto's disease 5

These tests, combined with a physical exam and medical history review, form the basis for diagnosing Hashimoto's disease. Note: This panel only contains the tests.

Understanding Hashimoto's Disease

Hashimoto's thyroiditis is an autoimmune disorder where the immune system attacks the thyroid gland, leading to hypothyroidism or, less commonly, hyperthyroidism. It's characterized by the presence of antibodies targeting the thyroid, leading to leukocyte accumulation and impaired hormone production. The thyroid, a vital gland in the neck, regulates energy use and various physiological processes.

Symptoms of Hashimoto's thyroiditis can be subtle initially but may progress to more noticeable signs of hypothyroidism, such as fatigue, weight gain, mood changes, slow heart rate, menstrual irregularities, cold sensitivity, facial swelling, difficulty conceiving, dry skin, and an enlarged thyroid gland. The severity of symptoms varies among individuals.

Causes and Risk Factors of Hashimoto's Disease

The underlying cause involves an immune response attacking the thyroid gland, leading to inflammation and damage. Genetic factors may also contribute. Risk factors include family history, exposure to radiation, certain environmental substances, hormonal changes, and viral infections. Understanding these factors is crucial for managing and preventing the condition.

Diagnosis and Treatment of Hashimoto's Disease

Diagnosis involves a combination of medical history, physical examination, and thyroid function tests (TFTs), including TSH, free T3, and free T4 levels, and antibody tests. Imaging techniques like ultrasounds may also be used.

Treatment options include thyroid hormone replacement therapy, primarily with levothyroxine. The dosage is tailored based on TSH levels. In severe cases, a thyroidectomy and lifelong hormone replacement therapy may be necessary.

Dietary Considerations and Specialist Care

Diet plays a significant role in managing Hashimoto's thyroiditis. Consuming nutrient-rich and fermented foods, along with sufficient vitamin C, supports immune function. Avoiding foods with gluten, soy, omega-6 fatty acids, and canola oil is often recommended.

Endocrinologists are the primary specialists for treating Hashimoto's thyroiditis, offering expertise in hormone-related disorders and personalized treatment plans.

For more detailed information, visit: Hashimoto's Disease Tests and Treatments

Citations

1. Hashimoto’s disease - Diagnosis & treatment - Mayo Clinic ¹
2. Hashimoto’s disease - Mayo Clinic²
3. Thyroid Antibodies: MedlinePlus Medical Test ³
4. How Hashimoto’s Disease Is Diagnosed - Verywell Health ⁴
5. How Thyroid Tests Can Improve Your Health - Cleveland Clinic

Categories: Fatigue Tests, Thyroid Tests, Metabolism Tests, Discounted Lab Panels,

Price: $179

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Comprehensive Fatigue Lab Panel

The causes of fatigue are multifactorial and could involve imbalances in several hormones. This panel includes most hormones and variables involved in the diagnosis and treatment of fatigue, including those related to irritable bowel syndrome. Ordering this panel provides substantial cost savings when compared to ordering each test separately. The panel is useful for men and women. TESTS INCLUDED IN THIS PANEL: TOTAL AND FREE TESTOSTERONE, THYROID FUNCTION: TSH, Free T3, Free T4, Thyroid Antibodies, HEMOGLOBIN A1c, Complete Blood Count (CBC) Test (includes white, red cells and platelets), Comprehensive Metabolic Panel (CMP), IRON, TIBC (Total Iron Binding Capacity), FERRITIN, ADRENAL FUNCTION: Cortisol and DHEA-S, and further testing and medical consultation may be required to determine the cause of abnormal results.

Boost Your Energy Levels with Comprehensive Fatigue Labs

The causes of fatigue are multifactorial and could involve imbalances in several hormones, including thyroid disorders. This panel includes most hormones and variables involved in the diagnosis and treatment of fatigue, including a comprehensive thyroid panel and physical examination to determine if your symptoms are connected to thyroid hormones or Hashimoto’s disease. Additionally, several hormone tests will be measured to assess for imbalances or thyroid dysfunction. Ordering this fatigue panel provides substantial cost savings when compared to ordering each test separately. The panel is useful for men and women in their journey towards achieving optimal wellness and understanding their test results. An A1c level, a full blood count (CBC) that checks for white blood cells, red blood cells, and platelets, a comprehensive metabolic panel (CMP), iron, tiBC (total iron binding capacity), ferritin, and adrenal function tests (cortisol and DHEA-S) are some of the tests that can be done. Practitioners frequently use these tests to establish a baseline for their patients' overall health and to aid in the management of underlying conditions that might be causing fatigue.

This is the lowest-cost fatigue exploration panel offered anywhere.

The causes of fatigue are multifactorial and could involve imbalances in several hormones. This panel, which includes most hormones and variables involved in the diagnosis and treatment of fatigue, provides substantial cost savings when compared to ordering each test separately. The panel is useful for men and women. We suggest that you also talk to your physician about getting an order for a sleep study to determine if you have sleep apnea. Additionally, be sure to download the corresponding lab order that you’ll need for testing and find the location near you for your blood and/or urine test.

Feeling tired and low on energy? Fatigue can be more than just a lack of sleep; it's often a sign of underlying health issues. Discounted Labs offers an extensive panel of tests specifically designed to uncover the hidden causes of extreme tiredness and fatigue, including the option of supplements to boost energy levels. With easy online ordering and no doctor visits required, understanding your health has never been more convenient.

Fatigue Labs Included:

TOTAL (LC/MS) AND FREE TESTOSTERONE (Equilibrium Dialysis) (No Upper Limit)

Are Low Testosterone Levels Draining Your Energy?

• Testosterone is crucial for energy and mood.
• Uncover if low testosterone is the reason behind your fatigue.

THYROID FUNCTION: The Hidden Culprit Behind Fatigue

Could Your Thyroid Be Slowing You Down?

Hypothyroidism is a prevalent condition that can cause fatigue, yet it is often ignored or misdiagnosed. The thyroid gland is responsible for producing hormones that regulate metabolism and energy levels in the body. When the thyroid gland does not produce enough hormones, it can lead to a feeling of constant tiredness and exhaustion. Other symptoms of hypothyroidism include weight gain, dry skin, and hair loss. Therefore, if you are experiencing persistent fatigue, it is essential to get your thyroid levels checked by a healthcare professional.

Our panel includes comprehensive thyroid tests:

• • TSH
  • Free T3
  • Free T4
  • Thyroid Antibodies

GLUCOSE CONTROL: Balancing Your Energy Levels

Is Your Blood Sugar Affecting Your Energy?

• Fluctuations in blood sugar levels can significantly impact your energy.

The A1c test is a straightforward method of assessing your glucose control. It measures the average blood sugar levels over the past two to three months and provides an overall picture of how well your diabetes management plan is working. The results of the A1c test can help you and your doctor adjust your treatment plan and make lifestyle modifications as necessary. Regular monitoring with this test is recommended to keep your diabetes under control and prevent complications.

• A Comprehensive Metabolic Panel (CMP) is a blood test that measures various components in the blood, including glucose levels. It is often used to assess a person's overall health and detect any underlying medical conditions. A fasting glucose level is typically measured as part of a CMP, which requires the individual to fast for at least 8 hours before the test. The results of this test can provide valuable information about a person's metabolic function and help identify potential health issues such as diabetes or liver disease.

ANEMIA AND IMMUNE ISSUES: The Blood Tells Your Story

Could Anemia or Infection Be Causing Your Fatigue?

Our complete blood count (CBC) panel provides a detailed picture:

• • White Blood Cells (WBC): Indicators of infection.
  • Red Blood Cells (RBC): Low count can signal anemia.
  • Hemoglobin (HGB) and Hematocrit (HCT): Key markers of anemia.
  • Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH), Mean Corpuscular Hemoglobin Concentration (MCHC): Crucial for understanding red blood cell health.
  • Red Cell Distribution Width (RDW): Helps pinpoint anemia types.
  • Platelets: Essential for blood clotting and healing.

IRON LEVEL, UTILIZATION, AND STORAGE: Are You Getting Enough Iron?

Iron Deficiency: A Common but Overlooked Cause of Fatigue

Ferritin Test

• • Fatigue labs offer ferritin testing to help diagnose the cause of fatigue. Ferritin is a protein found in cells that stores iron, and low levels of ferritin can indicate an iron deficiency. Iron deficiency can lead to fatigue, weakness, and difficulty concentrating. A ferritin test can help pinpoint the underlying cause of these symptoms and allow for appropriate treatment. In addition to ferritin testing, fatigue labs may also offer other tests to assess hormone levels, vitamin and mineral deficiencies, and thyroid function, among others.

Iron Deficiency (Iron and Total Iron Binding Capacity, TIBC)

• • Iron deficiency is a common cause of fatigue, especially in women. Fatigue Labs offers iron deficiency testing to help identify deficiencies and determine the best course of action for treatment. Iron is an essential mineral that plays a key role in carrying oxygen throughout the body. When there is not enough iron available, it can result in a reduction in the amount of oxygen transported, leading to fatigue and other symptoms. Our iron deficiency tests are quick and easy, allowing you to get the answers you need to address your fatigue and improve your overall health.

ADRENAL FUNCTION: The Stress-Fatigue Connection

Is your body's stress response contributing to fatigue?

• Adrenal insufficiency can lead to persistent tiredness.
  • Tests for adrenal health: serum cortisol
  • DHEA (blood)

Not included but worth considering as a separate add-on to your shopping cart: Vitamin D and Vitamin B-12.

NOTE: If you are taking biotin, please stop it 72 hours before the blood draw since it may interfere with hormone blood tests.

Add-ons for post-menopausal women: estrogen and progesterone.  Low estrogen levels, often found in menopause, often result in insomnia and night sweats. Diminished estrogen also causes irritability and mood swings in women, which furthers exhaustion. Too little progesterone is also linked to fatigue in women.

BACKGROUND INFORMATION ON THIS PANEL: FATIGUED? : BUY THESE BLOOD TESTS TO FIND OUT WHY 

Fatigue Labs : What Are They and Why Do You Need One?

Feeling fatigued is one of the most prevalent symptoms people experience daily. This is not a problem if you just worked out hard or didn't sleep well for days. Excessive or chronic fatigue is a real thing, and it can have serious underlying causes.

This is when blood tests for fatigue come into play. It's possible to test a blood sample and find out why you're feeling constantly tired, even after a good night's sleep. Please keep reading to learn more about fatigue, what conditions it might hide, and how blood tests, like the Fatigue Panel Blood Test, could help you investigate your chronic fatigue symptoms in daily life.

The Main Symptoms and Characteristics of Chronic Fatigue

The symptom of fatigue itself is something, but chronic fatigue is more complicated and may have additional symptoms. For example, many people feel tired without doing hard physical work. Others feel tired every day for weeks or even months on end.

It is challenging to participate in daily activities when suffering from chronic fatigue syndrome (CFS), which also causes a lack of energy and motivation. You aren't in the mood for anything, whether it's about going to work, spending time with your friends, or working out. If you cannot think of a potential reason for your chronic fatigue, chances are that it might have underlying causes related to disease control, making it crucial to seek a diagnosis of chronic fatigue syndrome. This information will greatly help your healthcare provider with the diagnostic process. Additionally, individuals with CFS may experience orthostatic intolerance, which can lead to dizziness upon standing due to blood pressure irregularities. Those who have CFS sleep poorly and awake unrefreshed. They frequently have headaches, muscle and joint pain, sore throats, problems concentrating and remembering things, and worsen with physical exertion.

Lifestyle choices, medical conditions, or excessive physical activity are frequently the causes of chronic fatigue. If you haven't worked out hard recently, chances are that the other two aspects might cause your tiredness.

For example, excessive drinking and smoking can make you feel tired. Not eating a balanced diet rich in fruit, vegetables, and lean meats can also make you feel fatigued. Lastly, not getting at least 7 hours of sleep every night might be the culprit for your constant tiredness.

Potential Medical Conditions That Cause Fatigue

If you sleep enough, don't smoke cigarettes, and eat a healthy diet but still feel fatigued, chances are that some underlying conditions are causing the problem. Certain medical conditions can leave you tired and lethargic all day.

For example, fibromyalgia is known for causing constant fatigue and mild pain in most muscles and joints of the body. The condition is rare, but it has no real cause and can decrease the quality of your life. It's possible to treat it using a particular medication and therapy, but you need to get a positive diagnosis for it first.

Arthritis is also known to cause excessive tiredness. This condition affects joints, tendons, and ligaments. It makes you feel lethargic and confused most of the time. Arthritis is common among seniors, but younger people can have it too.

Autoimmune disorders can also cause excessive fatigue. These are conditions that make the body fight itself. For example, celiac disease and lupus are prevalent autoimmune disorders that affect millions of people worldwide.

Your body spends a lot of energy fighting its own cells and tissues if you have an autoimmune disorder. Not only can this do severe damage, but you also have no energy left for anything else.

Chronic diseases, such as diabetes and liver disease, also cause fatigue. That's because the insulin your body produces is no longer able to unlock cells to absorb glucose from the blood. As a result, you're left with a lot of sugar in the blood and none in cells where it's supposed to be to give you energy. Anemia can also contribute to fatigue, as it is a condition characterized by a deficiency in red blood cells, or hemoglobin. One common nutritional cause of anemia is a deficiency in folate (vitamin B9). Additionally, shift work can also lead to fatigue, as extended periods of working during non-traditional hours can disrupt sleep patterns and result in decreased energy levels. Boredom and diminished motivation can also play a role in physiologic fatigue, as they can lead to decreased physical and mental activity, resulting in feelings of tiredness and lethargy. In cases where there is a suspicion of a serious underlying condition, further tests and referral to a specialist may be needed for proper diagnosis and treatment.

Finally, various types of cancer can also leave you without energy. That's because cells use this energy for abnormal mutations that can seriously threaten your health and life. Some cancers don't produce symptoms, and that's why you should run a blood test for fatigue as soon as possible.

How Can Blood Fatigue Labs Help?

The problem with chronic fatigue is that it can have multiple causes. It's not easy to identify the exact reason you feel tired. For example, some people might live under constant stress, and their cortisol levels are very high regularly. This could cause excessive tiredness in the long run.

You might feel tired because you also have an underactive thyroid gland. The hormones produced by the thyroid are responsible for your body's metabolism and energy production. If the thyroid is not producing enough hormones, you might lack energy and feel tired most of the time.

Some people feel fatigued because they also have too much or too little sugar in their bloodstream. Glucose is also known as blood sugar, and it's a vital energy source. If your body cannot metabolize glucose properly, you might feel lethargic every day.

Another helpful test for fatigue is a complete blood count test panel. This type of test looks at your red blood cells, hemoglobin, hematocrit, and other useful parameters related to your blood. If you don't have enough red blood cells, this could cause anemia, which means you'll feel tired.

You might also want to take a testosterone test if you feel tired and it's not related to the aforementioned factors. This vital hormone controls your energy level, cognition, and mood. If you have less testosterone than normal, you might experience chronic fatigue.

As you can see, there are a lot of tests that can be used to determine the cause of your tiredness. Your doctor might run these tests individually, or you can order a comprehensive panel of tests that looks at all these aspects at once.

By doing so, you will know for sure that the root cause of your tiredness will be discovered and diagnosed accurately. The comprehensive panel is highly recommended for people who have struggled with chronic fatigue for months or even years.

Order Your Fatigue Labs Today!

It's not fair to struggle with constant tiredness every day. Not only does it decrease the quality of your life, but it also reduces your productivity and makes you feel bad about yourself. You should order a fatigue blood test from your GP to see exactly why you're dealing with this problem. Empower yourself with knowledge! With Discounted Labs, getting tested is straightforward, affordable, and accessible in several U.S. states. No doctor visit is required, and you'll receive clear, easy-to-understand results. Take the first step towards a more energetic life today!

Common Questions

How do fatigue labs help in diagnosing medical conditions?

By carrying out various tests to determine the underlying causes of patients' fatigue, fatigue labs can assist in diagnosing medical conditions. These labs may perform blood tests to check for anemia, thyroid function, infections, or other abnormalities that could be contributing to the fatigue. Additionally, they may conduct sleep studies to assess for conditions like sleep apnea or insomnia that can impact energy levels. By analyzing the results of these tests and working closely with healthcare providers, fatigue labs play a crucial role in identifying and addressing medical conditions that may be causing fatigue in individuals.

What labs to order for fatigue, brain fog, anxiety?

When experiencing symptoms like fatigue, brain fog, and anxiety, it's important to consider ordering labs that can help identify potential underlying causes. Some common lab tests that may be ordered in this case include:

1. Complete Blood Count (CBC): This test provides information about the types and numbers of cells in your blood, which can help detect conditions like anemia or infections.

2. Thyroid Function Tests: These tests measure the levels of thyroid hormones in your blood and can help diagnose thyroid disorders that may contribute to these symptoms.

3. Vitamin D Levels: Low vitamin D levels have been associated with fatigue and mood disorders, so checking your vitamin D levels may be beneficial.

4. Comprehensive Metabolic Panel (CMP): This test evaluates various aspects of your overall health, including kidney function, liver function, and electrolyte levels.

5. Adrenal Function Tests: Cortisol levels and adrenal function tests can provide insights into how well your adrenal glands are functioning and if they are contributing to your symptoms.

It's important to consult with a healthcare provider to determine the most appropriate lab tests based on your specific symptoms and medical history.

Categories: Choose Your Test, Fatigue Tests, Discounted Lab Panels, Men's Health Tests,

Price: $432