Acute Myeloid Leukemia (AML), Rapid Mutation Panel
*Build Your Own Panel Eligible [?]
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$5032
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Description:
FLT3 testing is established as a prognostic marker associated with poor prognosis (high percentage of bone marrow blast cells, increased risk of relapse from CR, and reduced survival). However, with the advent of FLT3 inhibitors it is now also a test for targeted therapy in AML. The multi-kinase inhibitor Midostaurin, in combination with chemotherapy, is a targeted agent that significantly prolongs survival in patients with newly diagnosed FLT3-mutated AML and was recently approved by the Food and Drug Administration (FDA). Recently, the European LeukemiaNet recommends FLT3 testing (both tyrosine kinase domain; TKD and internal tandem duplication; ITD mutations) for all patients with AML, with results required within 3 days.In de novo AML, IDH1/2 mutations are associated with older age, normal karyotype, and NPM1 mutations. IDH1/2 and TET2 mutations are mutually exclusive. IDH1 mutations are found in 6-16% of de novo AML and are associated with a poorer outcome in patients treated with intensive chemotherapy, even in patients with favorable prognosis as per European LeukemiaNet (ELN) classification. IDH2 mutations are found in 8-19% of de novo AML. The prognostic impact of IDH2 mutations differs strongly and is less predictive overall. In the past 2 years, two mutant IDH (mutIDH) inhibitors, Enasidenib (AG-221), and Ivosidenib (AG-120), have been FDA-approved for IDH-mutant relapsed or refractory acute myeloid leukemia (AML) based on phase 1 safety and efficacy data and continue to be studied in trials in hematologic malignancies.NPM1 mutations have an overall favorable effect on the outcome for AML. Patients with FLT3-ITD and NPM1 mutations have improved outcomes when compared to patients with those who only have the FLT3-ITD mutation, but those with both mutations had a poorer prognosis than patients with only NPM1 mutations.CEBPA mutated AML into separates into 2 prognostic subsets: (1) CEBPA double-mutated AML and (2) CEBPA single-mutated AML. Favorable outcome was restricted to double-mutated AML cases and is an independent prognostic factor for a favorable outcome. FLT3-ITD, NPM1, ASXL1 and RUNX1 mutations are detected more frequently in CEBPA single-mutated AML.TP53 mutations correlate with poor response to chemotherapy and poor survival in patients with or without complex karyotype. There is a decreased frequency of FLT3, and NPM1 mutations in TP53 mutated AML.
Categories:
Price:
$5032
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Acute Myeloid Leukemia Prognostic Panel (Normal Karyotype)
*Build Your Own Panel Eligible [?]
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$2076
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Description:
This testing, consisting of FLT3, NPM-1, and CEBPA, is recommended in the NCCN guidelines for determination of AML risk status in patients with cytogenetically normal AML. The presence of CEBPA gene mutations is associated with increased disease-free survival and overall survival. Mutations in NPM1 gene is a predictor of favorable prognosis and good response to induction chemotherapy. The presence of (FLT3) internal tandem duplication is associated with short disease-free survival.
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Price:
$2076
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Acute Pancreatitis Panel
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$65
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Description:
Pancreatitis is a condition that occurs when the pancreas, an organ behind the stomach, becomes swollen and painful.
The pancreas produces digestive enzymes and insulin. The digestive enzymes flow into the small intestine to help break down food. Insulin is released into the blood to control the level of sugar (glucose) in the blood.
Significant deviations from the normal range may require further evaluation by your physician.
Includes:
Amylase, Serum
Lipase, Serum
Categories:
Gastrointestinal diseases,
Price:
$65
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Acylcarnitine, Plasma
*Build Your Own Panel Eligible [?]
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$454
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Description:
Elevation of one or more acylcarnitines is diagnostic for an organic aciduria or a fatty disorder. A low carnitine level may mask a disease state.
Categories:
Price:
$454
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Acylglycines, Quantitative Panel, Urine
*Build Your Own Panel Eligible [?]
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$860
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Description:
Acylglycines are an important class of metabolites that are used in the diagnosis of several organic acidurias and mitochondrial fatty acid oxidation disorders. This test is intended for the diagnosis and monitoring of several organic acidemias and fatty acid disorders affecting multiple metabolic pathways. Disorders diagnosed by Acylglycines assay: Isovaleric acidemia 3-Methylcrotonyl-Co-A-carboxylase deficiency Short-chain acyl-CoA dehydrogenase(SCAD) deficiency Ethylmalonic Encephalopathy Propionic acidemia Glutaric aciduria type-1, 2 and 3 Medium-chain acyl-CoA dehydrogenase(MCAD) Beta-ketothiolase deficiency 17-Beta-hydroxysteroid dehydrogenase deficiency Isobutyryl-CoA dehydrogenase deficiency Short/branched-chain acyl-CoA dehydrogenase deficiency (SBCADD) The test will also allow physicians to determine dietary compliance or the effectiveness of dietary/cofactor therapy for their patients. It can also be used, alone or in conjunction with other tests, to confirm the findings of a positive expanded newborn screen.
Categories:
Price:
$860
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Adalimumab Anti-drug Antibody for IBD
*Build Your Own Panel Eligible [?]
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$548
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Description:
Detectable serum adalimumab anti-drug antibody may cause accelerated adalimumab clearance leading to reduced trough levels of adalimumab and a compromised clinical response. Patients with low trough adalimumab level and anti-drug antibody are more likely to benefit from a switch in biologic therapy than from an increase in adalimumab dose. If adalimumab level is therapeutic and total adalimumab anti-drug antibody is detected, adalimumab anti-drug antibody may accelerate clearance of the drug, but the detected anti-drug antibody may not be clinically significant. The anti-drug antibody may not be functional or the level is inadequate to accelerate adalimumab clearance. For adalimumab responsive patients, anti-drug antibody may disappear over time or increase, and, if increased, may cause sub-therapeutic adalimumab levels and a loss of response in the future. Addition of immuno-suppressive agents to the treatment regimen may suppress development of anti-drug antibody. Quest Diagnostics adalimumab anti-drug antibody levels are determined with an assay that measures both free and bound anti-drug antibody. Therefore, serum rheumatoid factor will not cause false negative adalimumab anti-drug antibody results.
Categories:
Price:
$548
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Adalimumab Anti-drug Antibody for Rheumatic Diseases
*Build Your Own Panel Eligible [?]
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$548
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Description:
Detectable serum adalimumab anti-drug antibody may cause accelerated adalimumab clearance leading to reduced adalimumab trough levels and a compromised clinical response. Patients with low trough adalimumab level and anti-drug antibody are more likely to benefit from a switch in biologic therapy than from an increase in adalimumab dose. If adalimumab level is therapeutic and total adalimumab anti-drug antibody is detected, adalimumab anti-drug antibody may accelerate clearance of the drug, but the detected anti-drug antibody may not be clinically significant. The anti-drug antibody may not be functional or the level is inadequate to accelerate adalimumab clearance. For adalimumab responsive patients, anti-drug antibody may disappear over time or increase, and, if increased, may cause sub-therapeutic adalimumab levels and a loss of response in the future. Addition of methotrexate to the the treatment regimen may suppress development of anti-drug antibody. Quest Diagnostics adalimumab anti-drug antibody levels are determined with an assay that measures both free and bound anti-drug antibody. Therefore, serum rheumatoid factor will not cause false negative adalimumab anti-drug antibody results.
Categories:
Price:
$548
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Adalimumab Drug Level and Anti-drug Antibody for IBD
*Build Your Own Panel Eligible [?]
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$948
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Description:
The American Gastroenterological Association recommends optimal adalimumab trough concentration of 7.5 mcg/mL or greater in patients with active IBD. Data from separate clinical studies suggest an optimal adalimumab trough concentration greater than 4.5 mcg/mL or 8-12 mcg/mL. Sub-therapeutic adalimumab levels may be due to a patient not yet achieving a steady state trough level early in therapy, inadequate dosing, a dosing interval that is too long, or accelerated adalimumab clearance. Accelerated adalimumab clearance may be explained by the presence of adalimumab anti-drug antibody or rheumatoid factor in the patient's serum, or may be caused by other diseases that indirectly lead to immunoglobulin loss (i.e. kidney disease, protein-losing gastroenteropathy). If adalimumab level is sub-therapeutic but total adalimumab anti-drug antibody is not detected: Patients with a sub-therapeutic adalimumab trough level, but no anti-drug antibody, may benefit from an increased adalimumab dose. If adalimumab level is sub-therapeutic and total adalimumab anti-drug antibody is detected: Detectable serum adalimumab anti-drug antibody may cause accelerated adalimumab clearance leading to reduced trough levels and a compromised clinical response. Such patients are more likely to benefit from a switch in biologic therapy than from an increase in adalimumab dose. If adalimumab level is therapeutic and total adalimumab anti-drug antibody is not detected: In patients who do not respond or who lose their clinical response, mucosal inflammation is likely to be driven by a process that is not TNF alpha dependent. A switch to a different class of therapy should be considered. If adalimumab level is therapeutic and total adalimumab anti-drug antibody is detected: If the patient is responding clinically, the detected anti-drug antibody may not be clinically significant because the detected anti-drug antibody may not be functional or the level is inadequate to accelerate adalimumab clearance. Anti-drug antibody may disappear over time or increase, and, if increased, may cause sub-therapeutic adalimumab levels and a loss of response in the future. Patients with a loss of adalimumab response despite therapeutic trough levels may benefit from a switch to a different class of therapy.
Categories:
Price:
$948
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Adalimumab Drug Level and Anti-drug Antibody for Rheumatic Diseases
*Build Your Own Panel Eligible [?]
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$948
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Description:
Several studies suggest a target adalimumab trough concentration of 5-12 mcg/mL. Sub-therapeutic adalimumab levels may be due to a patient not yet achieving a steady state trough level early in therapy, inadequate dosing, a dosing interval that is too long, or accelerated adalimumab clearance. Accelerated adalimumab clearance may be explained by the presence of adalimumab anti-drug antibody or rheumatoid factor in the patient's serum, or may be caused by other diseases that indirectly lead to immunoglobulin loss (i.e. kidney disease, protein-losing gastroenteropathy). If adalimumab level is sub-therapeutic but total adalimumab anti-drug antibody is not detected: Patients with a sub-therapeutic adalimumab trough level, but no anti-drug antibody, may benefit from an increased adalimumab dose. If adalimumab level is sub-therapeutic and total adalimumab anti-drug antibody is detected: Detectable serum adalimumab anti-drug antibody may cause accelerated adalimumab clearance leading to reduced trough levels and a compromised clinical response. Such patients are more likely to benefit from a switch in biologic therapy than from an increase in adalimumab dose. If adalimumab level is therapeutic and total adalimumab anti-drug antibody is not detected: Patients who do not respond or who lose their clinical response, inflammation is likely to be driven by a process that is not TNF alpha dependent. A switch to a different class of therapy should be considered. If adalimumab level is therapeutic and total adalimumab anti-drug antibody is detected: If the patient is responding clinically, the detected anti-drug antibody may not be clinically significant because the detected anti-drug antibody may not be functional or the level is inadequate to accelerate adalimumab clearance. Anti-drug antibody may disappear over time or increase, and, if increased, may cause sub-therapeutic adalimumab levels and a loss of response in the future. Patients with a loss of adalimumab response despite therapeutic trough levels may benefit from a switch to a different class of therapy. Addition of methotrexate to the treatment regimen may suppress development of ADA.
Categories:
Price:
$948
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Adalimumab Level for IBD
*Build Your Own Panel Eligible [?]
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$548
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Description:
The American Gastroenterological Association recommends optimal adalimumab trough concentration of 7.5 mcg/mL or greater in patients with active IBD. Data from separate clinical studies suggest an optimal adalimumab trough concentration greater than 4.5 mcg/mL or 8-12 mcg/mL. Sub-therapeutic adalimumab levels may be due to a patient not yet achieving a steady state trough level early in therapy, inadequate dosing, a dosing interval that is too long or accelerated adalimumab clearance. Accelerated adalimumab clearance may be explained by the presence of adalimumab anti-drug antibody or rheumatoid factor in the patient's serum, or may be caused by other diseases that indirectly lead to immunoglobulin loss (i.e. kidney disease, protein-losing gastroenteropathy). If the steady state trough adalimumab level is low despite adequate dosing, adalimumab anti-drug antibody testing should be considered.
Categories:
Price:
$548
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Adalimumab Level for Rheumatic Diseases
*Build Your Own Panel Eligible [?]
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$548
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Description:
Several studies suggest a target adalimumab trough concentration of 5-12 mcg/mL. Sub-therapeutic adalimumab levels may be due to a patient not yet achieving a steady state trough level early in therapy, inadequate dosing, a dosing interval that is too long or accelerated adalimumab clearance. Accelerated adalimumab clearance may be explained by the presence of adalimumab anti-drug antibody or rheumatoid factor in the patient's serum, or may be caused by other diseases that indirectly lead to immunoglobulin loss (i.e. kidney disease, protein-losing gastroenteropathy). If the steady state trough Adalimumab level is low despite adequate dosing, adalimumab anti-drug antibody testing should be considered.
Categories:
Price:
$548
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ADAMTS13 Activity with Reflex to Inhibitor
*Build Your Own Panel Eligible [?]
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$344
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Description:
ADAMTS-13 is a zinc metalloprotease that cleaves ultra large vWF multimers. Studies have shown that low levels of ADAMTS-13 activity are associated with thrombotic thrombocytopenic purpura (TTP), a life-threatening hematological condition characterized by a low platelet count, microvascular thrombi, red cell fragmentation, and renal complications. Congenital TTP is a rare inherited disease caused by mutations within the ADAMTS-13 gene, which result in the production of non-functional protein. The acquired form of TTP is an autoimmune-like disorder caused by the development of autoantibodies to ADAMTS-13 that inhibits enzyme activity.Note: In the FDA approved test used at Quest Diagnostics, results are reported using international units (IU) per mL and not in percent (%), typically described in many studies. To convert to %, multiply IU/mL by 100%. For example, 0.3 IU/mL would be equivalent to 30% (0.3 IU/mL x 100%).
Categories:
Price:
$344
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Addison's Disease Screen (Basic)
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$251
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Description:
Addison's disease occurs when the adrenal glands (located above each kidney) do not work normally and do not produce enough hormones. Addison's disease may also be called chronic adrenal insufficiency or hypocortisolism.
This screen is used to aid in the diagnosis of Addison's disease.
Significant deviations from the normal range may require further evaluation by your physician.
Includes:
Adrenal Antibody Screen with Reflex to Titer
Adrenocorticotropic Hormone (ACTH)
Complete Blood Count / CBC (includes Differential and Platelets): WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet Count, MPV and Differential (Absolute and Percent - Neutrophils, Lymphocytes, Monocytes, Eosinophils, and Basophils)
Comprehensive Metabolic Profile ( includes eGFR ): Albumin, Albumin/Globulin Ratio (calculated), Alkaline Phosphatase, ALT, AST, BUN/Creatinine Ratio (calculated), Calcium, Carbon Dioxide, Chloride, Creatinine with GFR Estimated, Globulin (calculated), Glucose, Potassium, Sodium, Total Bilirubin, Total Protein, Urea Nitrogen
Cortisol, Total
Magnesium, Serum
Uric Acid, Serum (Gout Test)
Urinalysis Complete Profile: Color; appearance; specific gravity; pH; protein; glucose; occult blood; ketones; leukocyte esterase; nitrite; bilirubin; urobilinogen; microscopic examination of urine sediment.
Patient Instructions:
Patient should fast for 12 hours preceding collection of specimen. ACTH should be drawn between 7 AM and 10 AM. If drawn at any other time, the reference ranges do not apply. Cortisol, Total not recommended when patient is on prednisone/prednisolone therapy due to cross reactivity with the antibody used in this assay. Uric Acid, Serum recommends to discuss discontinuing drugs causing increased uric acid concentration include diurectics, pyrazinamide, ethambutol, and nicotinic acid with your primary care physician before testing.
Estimated turnaround for results is 10 business days. If confirmation testing is required, the estimated time may be extended.
Categories:
Hormones & metabolism,
Kidney diseases,
Price:
$251
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Adenovirus Antigenย Detection, Gastroenteritis, EIA
*Build Your Own Panel Eligible [?]
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$225
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Description:
Adenovirus causes respiratory tract infections, conjunctivitis, and diarrhea. Infections are most common in individuals who are immunocompromised and in young children. Adenovirus antigen detection is useful to confirm the diagnosis of adenovirus infection in patients with gastroenteritis.
Categories:
Price:
$225
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Adenovirus Antigen, DFA
*Build Your Own Panel Eligible [?]
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$301
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Description:
Respiratory viruses are responsible for a significant proportion of illness in human populations. Diagnosis may facilitate appropriate selection of specific antiviral drug therapy, prevent inappropriate use of antibiotics and guide patient management decisions.
Categories:
Price:
$301
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Adenovirus DNA, Qualitative, Real-Time PCR
*Build Your Own Panel Eligible [?]
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$415
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Description:
This test is designed to detect multiple strains of adenovirus, including adenovirus 40 and 41, but it does not differentiate among strains. Organisms may be detected by PCR prior to diagnosis by immunological methods. PCR provides more rapid results than other methods and is the preferred method for the detection of acute adenovirus infection.
Categories:
Price:
$415
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Adenovirus DNA, Quantitative Real-Time PCR
*Build Your Own Panel Eligible [?]
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$770
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Description:
This test is used to determine the presence of Adenovirus in a patient's specimen. Organisms may be detected by PCR prior to diagnosis by immunological methods. PCR provides more rapid results than other methods, including culture.
Categories:
Price:
$770
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Adenovirus, IHC with Interpretation
*Build Your Own Panel Eligible [?]
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$442
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Description:
Identifies adenovirus in FFPE tissue.
Categories:
Price:
$442
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Adenovirus, IHC without Interpretation
*Build Your Own Panel Eligible [?]
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$370
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Description:
Identifies adenovirus in FFPE tissue.
Categories:
Price:
$370
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ADHD Test
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$245
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Description:
Discover a new level of clarity and focus as you gain insight into your body with ADHD testing. Our state-of-the-art blood analysis provides an accurate and comprehensive view of adult ADHD by testing markers, helping you and your healthcare provider tailor a treatment plan specific to your needs. Keep in mind, our tests are not meant to diagnose ADHD, but rather to identify symptoms to allow you to optimize treatment results with your primary care doctor and at home. Say goodbye to frustration and hello to a brighter future, with ADHD blood testing. ADHD is a psychiatric condition that affects concentration and results in difficulty staying still or quiet. Although an ADHD diagnosis can only be determined through psychiatric evaluation, several disorders can make ADHD symptoms worse or impede effective treatment. Some of these include thyroid disorders, vitamin and mineral deficiencies, and food sensitivities.ย If you already have an ADHD diagnosis, you should get comprehensive testing for liver and kidney function, as treatment may result in severe side effects.ย The following panel has been tailored to cover ADHD patientsโ needs.
Includes:
Ferritin, serum.
Lead, Blood
Magnesium, serum
T3 Uptake; T4 (Thyroxine), Total; Free T4 Index (T7); Thyroid-Stimulating Hormone (TSH)
Total Iron,
Iron Binding Capacity,
% Saturation (calculated)
Reticulocyte Count
Vitamin B12
Vitamin D, 25-OH, Total;
Vitamin D, 25-OH, D3;
Vitamin D, 25-OH, D2
Zinc
Patient Instructions:
You should fast for 12 hours before collection of the specimen. Fasting is defined as no consumption of food or beverage other than water for at least 12 hours before testing. In patients receiving therapy with high biotin doses (ie, > 5 mg/day), no sample should be taken until at least eight hours after the last biotin administration.
Estimated turnaround for results is 5 business days. If confirmation testing is required, the estimated time may be extended.
Categories:
Price:
$245
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Adiponectin(1)
*Build Your Own Panel Eligible [?]
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$451
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Description:
Adipocytes (fat cells) express a variety of proteins that function in the homeostatic control of glucose and lipid metabolism. Insulin regulates the translocation and secretion of many of these proteins in response to changes in energy balance. Adiponectin is a protein whose secretion from adipocytes is enhanced by insulin stimulation. It has been suggested that the development of non-insulin dependent (Type II) diabetes may involve dysregulation of adiponectin secretion. In support of the link between obesity and Type II diabetes, it has been shown that decreased expression of adiponectin correlates with insulin resistance, and that adiponectin appears to be a potent insulin enhancer linking adipose tissue and whole-body glucose metabolism.
โข Individuals with low adiponectin levels have a 3X greater risk of developing metabolic syndrome [1].
โข Men with two or more risk factors for metabolic syndrome and high adiponectin levels are half as likely to develop metabolic syndrome as men with low adiponectin levels [2].
โข Individuals with low levels of adiponectin are up to 9X as likely to develop type 2 diabetes [3].
โข Individuals with low adiponectin levels have a 2X increase in the prevalence of CAD [4].
โข Adiponectin levels in the blood can be increased by thiazolidinediones, such as pioglitazone [5].
References:
1. Chen SJ et al. PLoS ONE. 2012; 7: e45693.
2. Kotooka N et al. Int J Cardiol. 2012 Nov 26. pii: S0167-5273(12)01441-6. doi:10.1016/j.ijcard.2012.10.066. [Epub ahead of print].
3. Daimon M et al. Diabetes Care. 2003; 26: 2015-2020.
4. Kumada M et al. Arterioscler Thromb Vasc Biol. 2003; 23: 35-39.
5. McCoy RG et al. Mayo Clin Proc. 2012; 87: 561-570.
Patient Instructions:
Fasting for 12 hours required.
Categories:
Heart & cholesterol,
Diabetes blood testing,
Price:
$451
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ADmarkยฎ ApoE Genotype Analysis and Interpretation (Symptomatic)
*Build Your Own Panel Eligible [?]
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$1156
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Description:
Detection of APOE2, E3, E4 alleles.
Categories:
Price:
$1156
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Adrenal Antibody Screen with Reflex to Titer
*Build Your Own Panel Eligible [?]
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$133
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Description:
- Pinpoint the cause of your fatigue
- Reveal hidden adrenal issues effortlessly
- Clarify unexplained weight changes quickly
Includes:
Adrenal Antibody Screen with Reflex to Titer
Estimated turnaround for results is 7 business days. If confirmation testing is required the estimated time may be extended.
Categories:
Autoimmune diseases,
Price:
$133
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Adrenal Fatigue Advanced Profile
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$209
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Description:
Significant deviations from the normal range may require further evaluation by your physician.
Includes:
Adrenocorticotropic Hormone (ACTH)
Comprehensive Metabolic Profile ( includes eGFR ): Albumin, Albumin/Globulin Ratio (calculated), Alkaline Phosphatase, ALT, AST, BUN/Creatinine Ratio (calculated), Calcium, Carbon Dioxide, Chloride, Creatinine with GFR Estimated, Globulin (calculated), Glucose, Potassium, Sodium, Total Bilirubin, Total Protein, Urea Nitrogen
Cortisol, AM
Dehydroepiandrosterone (DHEA-s) Sulfate
DHEA (Dehydroepiandrosterone), Unconjugated, LC/MS/MS
Patient Instructions:
Patient should fast for 12 hours preceding collection of specimen. This test must be drawn between 7 AM and 10 AM. Assay is not recommended when patient is receiving prednisone/prednisolone therapy due to cross reactivity with the antibody used in this assay. Fasting is defined as no consumption of food or beverage other than water for at least 8 - 10 hours before testing. Some tests in this panel may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H or coenzyme R). Patient should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.
Estimated turnaround for results is 5 business days. If confirmation testing is required, the estimated time may be extended.
Categories:
Hormones & metabolism,
Price:
$209
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Adrenal Fatigue Basic Profile
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$103
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Description:
Significant deviations from the normal range may require further evaluation by your physician.
Includes:
Adrenocorticotropic Hormone (ACTH)
Cortisol, AM
Patient Instructions:
Specimen should be collected between 7 AM and 9 AM. Assay is not recommended when patient is receiving prednisone/prednisolone therapy due to cross reactivity with the antibody used in this assay.
Categories:
Hormones & metabolism,
Price:
$103
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Adrenocorticotropic Hormone (ACTH)
*Build Your Own Panel Eligible [?]
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$87
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Description:
Adrenocorticotropic Hormone (ACTH) is a hormone produced by the pituitary gland. Determination of ACTH is useful in differentiating between primary and secondary adrenocortical hypo- and hyperfunctional disorders: Addison's disease, Cushing's syndrome, adrenal carcinoma, ectopic ACTH syndrome, and adrenal nodular hyperplasia.
Alternative Name(s): ACTH
A significant deviation from the normal range may require further evaluation by your physician.
Includes:
ACTH, Plasma
Patient Instructions:
ACTH should be drawn between 7 AM and 10 AM. If drawn at any other time, the reference ranges do not apply.
Categories:
Hormones & metabolism,
Price:
$87
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Advanced Heart & Metabolic Health Panel
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$399
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Description:
- Measure your heart attack risk early
- Assess if you could develop diabetes
- Evaluate stroke risk for peace of mind
Includes:
Cardio IQ Cholesterol, Total;
Cardio IQ HDL Cholesterol;
Cardio IQ Triglycerides;
Cardio IQ Non-HDL and Calculated Components;
Cardio IQ Lipoprotein Fractionation, Ion Mobility;
Cardio IQ Apolipoprotein B;
Cardio IQ Lipoprotein (a)
If Triglyceride is >400 mg/dL, Cardio IQ Direct LDL will be performed.
Patient Instructions:
No fasting needed. " According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hrs and a third dose of 100 mg/kg administered over 16 hrs. The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been determined to interfere with assays for cholesterol, uric acid" where "NAC interference may lead to falsely low results.
Estimated turnaround for results is 5 business days. If confirmation testing is required, the estimated time may be extended.
Categories:
Heart & cholesterol,
Price:
$399
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Advanced Lipid Panelย with Inflammation, Cardio IQยฎ
*Build Your Own Panel Eligible [?]
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$298
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Description:
The 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults recommend matching the intensity of statin treatment with the absolute risk of cardiovascular events. However, the standard lipid panel alone does not provide a complete assessment of absolute risk of CVD. Adding advanced CVD markers (ion mobility, apob, lp(a), hs crp and lppla2) in addition to the lipid panel will improve assessment of the CVD risk.
Categories:
Price:
$298
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Aerobic Bacterium Identification x2
*Build Your Own Panel Eligible [?]
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$90
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Description:
Organisms are evaluated according to clinical significance; If appropriate, the genus and species will be determined. The clinical significance of an isolate varies with the body site of origin and clinical symptoms manifested.
Categories:
Price:
$90
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Aerobic Bacterium Identification x3
*Build Your Own Panel Eligible [?]
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$136
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Description:
Organisms are evaluated according to clinical significance; If appropriate, the genus and species will be determined. The clinical significance of an isolate varies with the body site of origin and clinical symptoms manifested.
Categories:
Price:
$136
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Aerobic Bacterium Identification ย x4
*Build Your Own Panel Eligible [?]
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$181
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Description:
Organisms are evaluated according to clinical significance. If appropriate, the genus and species will be determined. The clinical significance of an isolate varies with the body site of origin and clinical symptoms manifested.
Categories:
Price:
$181
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Alanine Aminotransferase ALT (formally known as SGPT)
*Build Your Own Panel Eligible [?]
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$39
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Description:
Alanine Aminotransferase (ALT) measurements are particularly useful in the diagnosis and management of certain liver diseases, e.g., viral hepatitis and cirrhosis. ALT activity in tissue is generally much lower than aspartate aminotransferase (AST) activity and is found in highest concentrations in the liver. Significant elevations of ALT occur only in diseases of the liver. ALT is often measured in conjunction with AST to determine whether the source of the AST is the liver or the heart. ALT is normally not elevated in cases of myocardial infarction, i.e., a normal ALT, in conjunction with an elevated AST, tends to suggest cardiac disease. However, slight elevations of ALT may occur if an infarct destroys a very large volume of heart muscle.
Includes:
Alanine Aminotransferase (ALT/SGPT)
****Alanine Aminotransferase (ALT/SGPT) is included in the Comprehensive Metabolic Profile (CMP) and in the Liver Function Profile.***
Categories:
Liver diseases,
Price:
$39
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Albumin
*Build Your Own Panel Eligible [?]
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$39
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Description:
Serum albumin measurements are used in the monitoring and treatment of numerous diseases involving those related to nutrition and pathology particularly in the liver and kidney. Serum albumin is valuable when following response to therapy where improvement in the serum albumin level is the best sign of successful medical treatment. There may be a loss of albumin in the gastrointestinal tract, in the urine secondary to renal damage or direct loss of albumin through the skin. More than 50% of patients with gluten enteropathy have depressed albumin. The only cause of increased albumin is dehydration; there is no naturally occurring hyperalbuminemia.
Includes:
Albumin
****Albumin, serum is included in the Comprehensive Metabolic Profile (CMP), the Liver Function Profile and the Kidney Function Profile.***
Categories:
Liver diseases,
Blood and blood diseases,
Hormones & metabolism,
Kidney diseases,
Price:
$39
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Albumin, 24-Hour Urine with Creatinine
*Build Your Own Panel Eligible [?]
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$49
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Description:
Albumin excreted in the urine (Microalbumin) is a sensitive marker of Nephropathy. It is used to screen for early renal disease in diabetic patients.
Categories:
Price:
$49
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Albumin, 24-Hour Urine without Creatinine
*Build Your Own Panel Eligible [?]
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$49
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Description:
Albumin excreted in the urine (Microalbumin) is a sensitive marker of nephropathy. It is used to screen for early renal disease in diabetic patients.
Categories:
Price:
$49
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Albumin/Creatinine Ratio, Timed Urine
*Build Your Own Panel Eligible [?]
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$111
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Description:
This test measures the amount of albumin, a large protein, in urine. The presence of albumin in urine may be useful as an early marker of kidney damage. Because the kidneys usually excrete only small molecules into urine, even low levels of albumin in urine (microalbuminuria) may suggest kidney injury [1]. According to the Centers for Disease Control and Prevention (CDC), diabetes and high blood pressure are the major causes of chronic kidney disease (CKD). The CDC recommends regular testing for CKD in people who have diabetes, high blood pressure, and/or other risk factors, such as heart disease, family history of CKD, obesity, previous damage to the kidneys, and older age. The albumin/creatinine ratio is an important part of this assessment [2,3]. Microalbuminuria is a known risk factor for progressive kidney disease and cardiovascular death [4]. The National Kidney Foundation (NKF) recommends annual testing for microalbumin/albumin in all individuals with diabetes whose kidneys are functioning. According to the NKF, annual testing should start 5 years after diagnosis for individuals with type 1 diabetes and at diagnosis for individuals with type 2 diabetes [5]. The NKF recommends that at least 2 of 3 specimens, drawn within a 3- to 6-month period, be reported as abnormal before making a clinical diagnosis of either microalbuminuria or albuminuria [5]. Results are reported as a ratio of albumin (ยตg) to creatinine (mg). Test results should be interpreted in the context of pertinent clinical and family history and physical examination findings. References 1. Burtis C, et al. Amino acids and proteins. In: Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics. 7th ed. St Louis, MO: Elsevier; 2015:314-315. 2. Gaitonde DY, et al. Am Fam Physician. 2017;96:776-783. 3. Centers for Disease Control and Prevention. Chronic kidney disease in the United States, 2019. https://www.cdc.gov/kidneydisease/publications-resources/2019-national-facts.html. Last reviewed March 11, 2019. Accessed February 4, 2020. 4. Weir, MR. Clin J Am Soc Nephrol. 2007;2:581-590. 5. National Kidney Foundation. Am J Kidney Dis. 2007(Suppl 2);49:S1-S180.
Categories:
Price:
$111
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Albumin, Random Urine without Creatinine
*Build Your Own Panel Eligible [?]
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$49
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Description:
Albumin excreted in the urine (Microalbumin) is a sensitive marker of nephropathy. It is used to screen for early renal disease in diabetic patients.
Categories:
Price:
$49
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Albumin, Timed Urine
*Build Your Own Panel Eligible [?]
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$49
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Description:
Albumin excreted in the urine (Microalbumin) is a sensitive marker of nephropathy. It is used to screen for early renal disease in diabetic patients.
Categories:
Price:
$49
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Alcohol, Ethyl
*Build Your Own Panel Eligible [?]
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$326
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Description:
- Check current blood alcohol level
- Confirm recent alcohol consumption privately
- Monitor sobriety and drinking habits
Categories:
Price:
$326
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Alcohol, Methyl
*Build Your Own Panel Eligible [?]
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$293
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Description:
Methanol can be consumed intentionally or accidentally. It is an ingredient in antifreeze, cleaning fluids and is used as a solvent. The CNS effects of methanol are less than ethanol. However, this substance is far more toxic since ingestion can lead to acidosis and optic neuropathy which can result in blindness or death. Methanol is oxidized to formaldehyde.
Categories:
Price:
$293
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Alder (t2) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This test quantifies an individual's IgE response to alder. Allergen-specific serum IgE testing is considered comparable to skin testing and may be preferred in some clinical situations. However, a positive test result only indicates that a patient is sensitized to the allergen of concern. Many IgE-sensitized individuals do not develop any symptoms when exposed to the allergen. A diagnosis of allergy should only be made by a trained medical provider after conducting a thorough clinical evaluation [1].More specific information about this allergen can be found on the following website: https://www.thermofisher.com/phadia/us/en/resources/allergen-encyclopedia.htmlReference 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.
Categories:
Price:
$49
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Aldolase
*Build Your Own Panel Eligible [?]
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$77
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Description:
Aids in the diagnosis of primary disease of skeletal muscle myocardial infarction and viral hepatitis.
Alternative names: Fructose-1,6 bisphospate
Categories:
Neurology,
Price:
$77
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Aldolase
*Build Your Own Panel Eligible [?]
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$81
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Description:
- Measures muscle enzyme levels.
- Checks for muscle damage.
- Assesses muscle health.
Includes:
Aldolase
Categories:
Price:
$81
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Aldosterone, 24-Hourย Urine
*Build Your Own Panel Eligible [?]
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$265
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Description:
Aldosterone is a hormone produced by the adrenal glands. Patients with primary hyperaldosteronism exhibit hypokalemia, hypertension, and low direct renin concentrations.
Categories:
Price:
$265
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Aldosterone, Adrenal Vein
*Build Your Own Panel Eligible [?]
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$574
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Description:
Approximately 1-2% of individuals with primary hypertension have primary hyperaldosteronism characterized by hypokalemia (low potassium) and low direct renin. Because serum aldosterone concentrations vary due to dietary sodium intake and body positions, some physicians prefer measurement of 24-hour urine concentrations for aldosterone.
Categories:
Price:
$574
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Aldosterone/Cortisol Ratio, Adrenal Vein Sampling, 1 Site
*Build Your Own Panel Eligible [?]
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$499
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Description:
Measurements of aldosterone/cortisol ratios in specimens from adrenal venous blood, obtained by an experienced radiologist, is the "gold standard" test to distinguish between an adenoma or unilateral hyperplasia and bilateral hyperplasia. Unilateral disease is associated with a marked (usually greater than four-fold) increase in the aldosterone/cortisol ratio on the side of the tumor, whereas there is little difference between the two sides in patients with bilateral hyperplasia. AVS (adrenal vein sampling) with aldosterone/cortisol measurement is indicated if imaging studies fail to unequivocally identify an adenoma or if the identified adenoma is <1 cm in size.
Categories:
Price:
$499
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Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS
*Build Your Own Panel Eligible [?]
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$150
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Description:
Measurement of renin activity is useful in the differential diagnosis of individuals with hypertension. Renin levels will be elevated in patients with hypertension due to renal artery stenosis (ie, renovascular hypertension). Also useful in the diagnosis of primary aldosteronism. Patients with secondary aldosteronism tend to have low renin levels. Renin can also be used to assess the adequacy of steroid substitution in patients with adrenal insufficiency. Renin activity will be normal in patients with adequate supplementation and will be elevated when steroid substitution is inadequate.
Significant deviations from the normal range may require further evaluation by your physician.
Includes:
Aldosterone, LC/MS
Plasma Renin Activity, LC/MS/MS
Aldo/Pra Ratio
Estimated turnaround for results is 5 business days. If confirmation testing is required, the estimated time may be extended.
Patient Instructions:
No fasting needed.
Categories:
Kidney diseases,
General wellness,
Hormones & metabolism,
Price:
$150
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Aldosterone serum
*Build Your Own Panel Eligible [?]
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$143
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Description:
- Checks hormone for blood pressure control.
- Measures salt and water balance hormone.
- Evaluates kidney and adrenal gland function.
Patient Instructions:
No fasting needed.
Categories:
Price:
$143
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Alkaline Phosphatase, Bone Specific
*Build Your Own Panel Eligible [?]
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$350
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Description:
- Checks bone health and growth.
- Measures bone enzyme levels.
- Assesses bone-related enzyme activity.
Includes:
Alkaline Phosphatase, Bone Specific
Categories:
Price:
$350
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Alkaline phosphatase isoenzymes
*Build Your Own Panel Eligible [?]
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$203
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Description:
When the Total Alkaline Phosphatase activity is increased, the Isoenzymes are useful in determining the source of the increased activity.
Patient Instructions:
No fasting needed.
Categories:
Price:
$203
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