Comprehensive Metabolic Panel with Adjusted Calcium
*Build Your Own Panel Eligible [?]
|
$49
|
|
|
Description:
This panel comprises a group of tests that provide information on an individual's blood levels of electrolytes, calcium, and glucose as well as renal function, hepatic function, and acid-base balance. The panel is usually ordered as part of a health examination to detect a range of disorders, especially those that may affect the liver or kidneys [1].The results of the panel components are usually evaluated jointly for patterns. The section below outlines the roles of the analytes assessed with this panel [1].Sodium: An electrolyte that plays a central role in maintaining the normal distribution of water and appropriate pressure to assure that substances do not leak from cells and organs. Sodium measurements are useful in the diagnosis and treatment of diseases involving electrolyte imbalance.Potassium: An electrolyte that is essential for proper muscle and nerve function and helps keep the balance of fluids. Potassium measurements are useful in assessing electrolyte balance in the diagnosis and treatment of conditions characterized by low or high blood potassium levels.Chloride: An electrolyte that helps maintain volume, acidity, and electrical neutrality of the body fluids. Chloride measurements are useful in the diagnosis and treatment of electrolyte and metabolic disorders, such as cystic fibrosis and diabetic acidosis.Carbon dioxide (bicarbonate): A type of blood gas used to evaluate the total carbonate buffering system and acid-base balance. Carbon dioxide is generally evaluated with other common electrolytes; the measurements are useful in the diagnosis and treatment of numerous potentially serious disorders associated with changes in body acid-base balance.Glucose: A type of sugar that serves as the body's main energy source. Glucose measurements are useful in the diagnosis of diabetes and low blood sugar.Calcium: A mineral in the body that is essential for nerve, muscle, and heart functions and bone formation. Calcium measurements are useful in the diagnosis of parathyroid disease, some bone disorders, and chronic kidney disease. Adjusted calcium is useful in the interpretation of calcium levels when albumin levels are low.Blood urea nitrogen (BUN): The principal waste product of protein catabolism. BUN measurements are useful in the diagnosis and treatment of certain kidney and metabolic diseases.Creatinine: A waste product of the muscles. Creatinine measurements are useful in the evaluation of kidney function and in monitoring renal dialysis.Creatinine-based estimated glomerular filtration rate (eGFR): A value calculated using serum creatinine measurements and the patient's age and sex to reflect kidney function. eGFR is useful in detecting and monitoring chronic kidney disease in adults.Albumin: A protein that keeps fluid from leaking out of the blood and carries hormones, vitamins, and enzymes in the body. Albumin measurements are useful in the monitoring and treatment of numerous diseases involving primarily the liver and kidneys.Total bilirubin: A waste product generated when old red blood cells break down. Bilirubin measurements are useful in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease.Total protein: A sum of albumin and globulins. Protein measurements are useful in the diagnosis of disorders involving the liver, kidneys, or bone marrow.Alkaline phosphatase: An enzyme found mainly in the liver, bones, kidneys, and digestive system. Alkaline phosphatase measurements are useful in the diagnosis of hepatobiliary disorders and bone diseases associated with increased bone formation.Aspartate aminotransferase (AST): An enzyme widely distributed throughout the tissues, with significant amounts present in the heart and liver. AST measurements are useful in the evaluation of liver and heart damage.Alanine aminotransferase (ALT): An enzyme found in highest concentrations in the liver and often measured in conjunction with AST. ALT measurements are useful in the diagnosis and management of certain liver diseases (eg, viral hepatitis and cirrhosis). Very high values may be associated with hepatitis, though some people with hepatitis have ALT values within the reference interval.References1. Rao LV, et al. Laboratory tests. In: Rao LV, eds. Wallach's Interpretation of Diagnostic Tests. Pathways to Arriving at a Clinical Diagnosis. 11th ed. Wolters Kluwer; 2020.
Categories:
Price:
$49
|
Comprehensive Metabolic Panel with Adjusted Calcium, Plasma
*Build Your Own Panel Eligible [?]
|
$49
|
|
|
Description:
This panel comprises a group of tests that provide information on an individual's blood levels of electrolytes, calcium, and glucose as well as renal function, hepatic function, and acid-base balance. The panel is usually ordered as part of a health examination to detect a range of disorders, especially those that may affect the liver or kidneys [1].The results of the panel components are usually evaluated jointly for patterns. The section below outlines the roles of the analytes assessed with this panel [1].Sodium: An electrolyte that plays a central role in maintaining the normal distribution of water and appropriate pressure to assure that substances do not leak from cells and organs. Sodium measurements are useful in the diagnosis and treatment of diseases involving electrolyte imbalance.Potassium: An electrolyte that is essential for proper muscle and nerve function and helps keep the balance of fluids. Potassium measurements are useful in assessing electrolyte balance in the diagnosis and treatment of conditions characterized by low or high blood potassium levels.Chloride: An electrolyte that helps maintain volume, acidity, and electrical neutrality of the body fluids. Chloride measurements are useful in the diagnosis and treatment of electrolyte and metabolic disorders, such as cystic fibrosis and diabetic acidosis.Carbon dioxide (bicarbonate): A type of blood gas used to evaluate the total carbonate buffering system and acid-base balance. Carbon dioxide is generally evaluated with other common electrolytes; the measurements are useful in the diagnosis and treatment of numerous potentially serious disorders associated with changes in body acid-base balance.Glucose: A type of sugar that serves as the body's main energy source. Glucose measurements are useful in the diagnosis of diabetes and low blood sugar.Calcium: A mineral in the body that is essential for nerve, muscle, and heart functions and bone formation. Calcium measurements are useful in the diagnosis of parathyroid disease, some bone disorders, and chronic kidney disease. Adjusted calcium is useful in the interpretation of calcium levels when albumin levels are low.Blood urea nitrogen (BUN): The principal waste product of protein catabolism. BUN measurements are useful in the diagnosis and treatment of certain kidney and metabolic diseases.Creatinine: A waste product of the muscles. Creatinine measurements are useful in the evaluation of kidney function and in monitoring renal dialysis.Creatinine-based estimated glomerular filtration rate (eGFR): A value calculated using serum creatinine measurements and the patient's age and sex to reflect kidney function. eGFR is useful in detecting and monitoring chronic kidney disease in adults.Albumin: A protein that keeps fluid from leaking out of the blood and carries hormones, vitamins, and enzymes in the body. Albumin measurements are useful in the monitoring and treatment of numerous diseases involving primarily the liver and kidneys.Total bilirubin: A waste product generated when old red blood cells break down. Bilirubin measurements are useful in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease.Total protein: A sum of albumin and globulins. Protein measurements are useful in the diagnosis of disorders involving the liver, kidneys, or bone marrow.Alkaline phosphatase: An enzyme found mainly in the liver, bones, kidneys, and digestive system. Alkaline phosphatase measurements are useful in the diagnosis of hepatobiliary disorders and bone diseases associated with increased bone formation.Aspartate aminotransferase (AST): An enzyme widely distributed throughout the tissues, with significant amounts present in the heart and liver. AST measurements are useful in the evaluation of liver and heart damage.Alanine aminotransferase (ALT): An enzyme found in highest concentrations in the liver and often measured in conjunction with AST. ALT measurements are useful in the diagnosis and management of certain liver diseases (eg, viral hepatitis and cirrhosis). Very high values may be associated with hepatitis, though some people with hepatitis have ALT values within the reference interval.References1. Rao LV, et al. Laboratory tests. In: Rao LV, eds. Wallach's Interpretation of Diagnostic Tests. Pathways to Arriving at a Clinical Diagnosis. 11th ed. Wolters Kluwer; 2020.
Categories:
Price:
$49
|
Comprehensive Metabolic Panel with Fibrosis-4 (FIB-4) Index
*Build Your Own Panel Eligible [?]
|
$49
|
|
|
Description:
The FIB-4 index is a simple non-invasive approach using selected laboratory measures (AST, ALT, platelet count) in combination with patient age to assess if an individual is at higher risk for advanced liver fibrosis (F3-F4).
Categories:
Price:
$49
|
Comprehensive Metabolic Panel without ALT
*Build Your Own Panel Eligible [?]
|
$49
|
|
|
Description:
This panel comprises a group of tests that provide information on an individual's blood levels of electrolytes, calcium, and glucose as well as renal function, hepatic function, and acid-base balance. The panel is usually ordered as part of a health examination to detect a range of disorders, especially those that may affect the liver or kidneys [1].The results of the panel components are usually evaluated jointly for patterns. The section below outlines the roles of the analytes assessed with this panel [1].Sodium: An electrolyte that plays a central role in maintaining the normal distribution of water and appropriate pressure to assure that substances do not leak from cells and organs. Sodium measurements are useful in the diagnosis and treatment of diseases involving electrolyte imbalance.Potassium: An electrolyte that is essential for proper muscle and nerve function and helps keep the balance of fluids. Potassium measurements are useful in assessing electrolyte balance in the diagnosis and treatment of conditions characterized by low or high blood potassium levels.Chloride: An electrolyte that helps maintain volume, acidity, and electrical neutrality of the body fluids. Chloride measurements are useful in the diagnosis and treatment of electrolyte and metabolic disorders, such as cystic fibrosis and diabetic acidosis.Carbon dioxide (bicarbonate): A type of blood gas used to evaluate the total carbonate buffering system and acid-base balance. Carbon dioxide is generally evaluated with other common electrolytes; the measurements are useful in the diagnosis and treatment of numerous potentially serious disorders associated with changes in body acid-base balance.Glucose: A type of sugar that serves as the body's main energy source. Glucose measurements are useful in the diagnosis of diabetes and low blood sugar.Calcium: A mineral in the body that is essential for nerve, muscle, and heart functions and bone formation. Calcium measurements are useful in the diagnosis of parathyroid disease, some bone disorders, and chronic kidney disease.Blood urea nitrogen (BUN): The principal waste product of protein catabolism. BUN measurements are useful in the diagnosis and treatment of certain kidney and metabolic diseases.Creatinine: A waste product of the muscles. Creatinine measurements are useful in the evaluation of kidney function and in monitoring renal dialysis.Creatinine-based estimated glomerular filtration rate (eGFR): A value calculated using serum creatinine measurements and the patient's age and sex to reflect kidney function. eGFR is useful in detecting and monitoring chronic kidney disease in adults.Albumin: A protein that keeps fluid from leaking out of the blood and carries hormones, vitamins, and enzymes in the body. Albumin measurements are useful in the monitoring and treatment of numerous diseases involving primarily the liver and kidneys.Total bilirubin: A waste product generated when old red blood cells break down. Bilirubin measurements are useful in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease.Total protein: A sum of albumin and globulins. Protein measurements are useful in the diagnosis of disorders involving the liver, kidneys, or bone marrow.Alkaline phosphatase: An enzyme found mainly in the liver, bones, kidneys, and digestive system. Alkaline phosphatase measurements are useful in the diagnosis of hepatobiliary disorders and bone diseases associated with increased bone formation.Aspartate aminotransferase (AST): An enzyme widely distributed throughout the tissues, with significant amounts present in the heart and liver. AST measurements are useful in the evaluation of liver and heart damage.References1. Rao LV, et al. Laboratory tests. In: Rao LV, eds. Wallach's Interpretation of Diagnostic Tests. Pathways to Arriving at a Clinical Diagnosis. 11th ed. Wolters Kluwer; 2020.
Categories:
Price:
$49
|
Comprehensive Metabolic Panel without ALT and Glomerular Filtration Rate, Estimated (eGFR)
*Build Your Own Panel Eligible [?]
|
$49
|
|
|
Description:
This panel comprises a group of tests that provide information on an individual's blood levels of electrolytes, calcium, and glucose as well as renal function, hepatic function, and acid-base balance. The panel is usually ordered as part of a health examination to detect a range of disorders, especially those that may affect the liver or kidneys [1].The results of the panel components are usually evaluated jointly for patterns. The section below outlines the roles of the analytes assessed with this panel [1].Sodium: An electrolyte that plays a central role in maintaining the normal distribution of water and appropriate pressure to assure that substances do not leak from cells and organs. Sodium measurements are useful in the diagnosis and treatment of diseases involving electrolyte imbalance.Potassium: An electrolyte that is essential for proper muscle and nerve function and helps keep the balance of fluids. Potassium measurements are useful in assessing electrolyte balance in the diagnosis and treatment of conditions characterized by low or high blood potassium levels.Chloride: An electrolyte that helps maintain volume, acidity, and electrical neutrality of the body fluids. Chloride measurements are useful in the diagnosis and treatment of electrolyte and metabolic disorders, such as cystic fibrosis and diabetic acidosis.Carbon dioxide (bicarbonate): A type of blood gas used to evaluate the total carbonate buffering system and acid-base balance. Carbon dioxide is generally evaluated with other common electrolytes; the measurements are useful in the diagnosis and treatment of numerous potentially serious disorders associated with changes in body acid-base balance.Glucose: A type of sugar that serves as the body's main energy source. Glucose measurements are useful in the diagnosis of diabetes and low blood sugar.Calcium: A mineral in the body that is essential for nerve, muscle, and heart functions and bone formation. Calcium measurements are useful in the diagnosis of parathyroid disease, some bone disorders, and chronic kidney disease.Blood urea nitrogen (BUN): The principal waste product of protein catabolism. BUN measurements are useful in the diagnosis and treatment of certain kidney and metabolic diseases.Creatinine: A waste product of the muscles. Creatinine measurements are useful in the evaluation of kidney function and in monitoring renal dialysis.Albumin: A protein that keeps fluid from leaking out of the blood and carries hormones, vitamins, and enzymes in the body. Albumin measurements are useful in the monitoring and treatment of numerous diseases involving primarily the liver and kidneys.Total bilirubin: A waste product generated when old red blood cells break down. Bilirubin measurements are useful in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease.Total protein: A sum of albumin and globulins. Protein measurements are useful in the diagnosis of disorders involving the liver, kidneys, or bone marrow.Alkaline phosphatase: An enzyme found mainly in the liver, bones, kidneys, and digestive system. Alkaline phosphatase measurements are useful in the diagnosis of hepatobiliary disorders and bone diseases associated with increased bone formation.Aspartate aminotransferase (AST): An enzyme widely distributed throughout the tissues, with significant amounts present in the heart and liver. AST measurements are useful in the evaluation of liver and heart damage.References1. Rao LV, et al. Laboratory tests. In: Rao LV, eds. Wallach's Interpretation of Diagnostic Tests. Pathways to Arriving at a Clinical Diagnosis. 11th ed. Wolters Kluwer; 2020.
Categories:
Price:
$49
|
Comprehensive Metabolic Panel without CO2, ALT
*Build Your Own Panel Eligible [?]
|
$49
|
|
|
Description:
This panel comprises a group of tests that provide information on an individual's blood levels of electrolytes, calcium, and glucose as well as renal function, hepatic function, and acid-base balance. The panel is usually ordered as part of a health examination to detect a range of disorders, especially those that may affect the liver or kidneys [1].The results of the panel components are usually evaluated jointly for patterns. The section below outlines the roles of the analytes assessed with this panel [1].Sodium: An electrolyte that plays a central role in maintaining the normal distribution of water and appropriate pressure to assure that substances do not leak from cells and organs. Sodium measurements are useful in the diagnosis and treatment of diseases involving electrolyte imbalance.Potassium: An electrolyte that is essential for proper muscle and nerve function and helps keep the balance of fluids. Potassium measurements are useful in assessing electrolyte balance in the diagnosis and treatment of conditions characterized by low or high blood potassium levels.Chloride: An electrolyte that helps maintain volume, acidity, and electrical neutrality of the body fluids. Chloride measurements are useful in the diagnosis and treatment of electrolyte and metabolic disorders, such as cystic fibrosis and diabetic acidosis.Glucose: A type of sugar that serves as the body's main energy source. Glucose measurements are useful in the diagnosis of diabetes and low blood sugar.Calcium: A mineral in the body that is essential for nerve, muscle, and heart functions and bone formation. Calcium measurements are useful in the diagnosis of parathyroid disease, some bone disorders, and chronic kidney disease.Blood urea nitrogen (BUN): The principal waste product of protein catabolism. BUN measurements are useful in the diagnosis and treatment of certain kidney and metabolic diseases.Creatinine: A waste product of the muscles. Creatinine measurements are useful in the evaluation of kidney function and in monitoring renal dialysis.Creatinine-based estimated glomerular filtration rate (eGFR): A value calculated using serum creatinine measurements and the patient's age and sex to reflect kidney function. eGFR is useful in detecting and monitoring chronic kidney disease in adults.Albumin: A protein that keeps fluid from leaking out of the blood and carries hormones, vitamins, and enzymes in the body. Albumin measurements are useful in the monitoring and treatment of numerous diseases involving primarily the liver and kidneys.Total bilirubin: A waste product generated when old red blood cells break down. Bilirubin measurements are useful in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease.Total protein: A sum of albumin and globulins. Protein measurements are useful in the diagnosis of disorders involving the liver, kidneys, or bone marrow.Alkaline phosphatase: An enzyme found mainly in the liver, bones, kidneys, and digestive system. Alkaline phosphatase measurements are useful in the diagnosis of hepatobiliary disorders and bone diseases associated with increased bone formation.Aspartate aminotransferase (AST): An enzyme widely distributed throughout the tissues, with significant amounts present in the heart and liver. AST measurements are useful in the evaluation of liver and heart damage.References1. Rao LV, et al. Laboratory tests. In: Rao LV, eds. Wallach's Interpretation of Diagnostic Tests. Pathways to Arriving at a Clinical Diagnosis. 11th ed. Wolters Kluwer; 2020.
Categories:
Price:
$49
|
Comprehensive Metabolic Panel without CO2, ALT and Glomerular Filtration Rate, Estimated (eGFR)
*Build Your Own Panel Eligible [?]
|
$49
|
|
|
Description:
This panel comprises a group of tests that provide information on an individual's blood levels of electrolytes, calcium, and glucose as well as renal function, hepatic function, and acid-base balance. The panel is usually ordered as part of a health examination to detect a range of disorders, especially those that may affect the liver or kidneys [1].The results of the panel components are usually evaluated jointly for patterns. The section below outlines the roles of the analytes assessed with this panel [1].Sodium: An electrolyte that plays a central role in maintaining the normal distribution of water and appropriate pressure to assure that substances do not leak from cells and organs. Sodium measurements are useful in the diagnosis and treatment of diseases involving electrolyte imbalance.Potassium: An electrolyte that is essential for proper muscle and nerve function and helps keep the balance of fluids. Potassium measurements are useful in assessing electrolyte balance in the diagnosis and treatment of conditions characterized by low or high blood potassium levels.Chloride: An electrolyte that helps maintain volume, acidity, and electrical neutrality of the body fluids. Chloride measurements are useful in the diagnosis and treatment of electrolyte and metabolic disorders, such as cystic fibrosis and diabetic acidosis.Glucose: A type of sugar that serves as the body's main energy source. Glucose measurements are useful in the diagnosis of diabetes and low blood sugar.Calcium: A mineral in the body that is essential for nerve, muscle, and heart functions and bone formation. Calcium measurements are useful in the diagnosis of parathyroid disease, some bone disorders, and chronic kidney disease.Blood urea nitrogen (BUN): The principal waste product of protein catabolism. BUN measurements are useful in the diagnosis and treatment of certain kidney and metabolic diseases.Creatinine: A waste product of the muscles. Creatinine measurements are useful in the evaluation of kidney function and in monitoring renal dialysis.Albumin: A protein that keeps fluid from leaking out of the blood and carries hormones, vitamins, and enzymes in the body. Albumin measurements are useful in the monitoring and treatment of numerous diseases involving primarily the liver and kidneys.Total bilirubin: A waste product generated when old red blood cells break down. Bilirubin measurements are useful in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease.Total protein: A sum of albumin and globulins. Protein measurements are useful in the diagnosis of disorders involving the liver, kidneys, or bone marrow.Alkaline phosphatase: An enzyme found mainly in the liver, bones, kidneys, and digestive system. Alkaline phosphatase measurements are useful in the diagnosis of hepatobiliary disorders and bone diseases associated with increased bone formation.Aspartate aminotransferase (AST): An enzyme widely distributed throughout the tissues, with significant amounts present in the heart and liver. AST measurements are useful in the evaluation of liver and heart damage.References1. Rao LV, et al. Laboratory tests. In: Rao LV, eds. Wallach's Interpretation of Diagnostic Tests. Pathways to Arriving at a Clinical Diagnosis. 11th ed. Wolters Kluwer; 2020.
Categories:
Price:
$49
|
Comprehensive Metabolic Panel without Glomerular Filtration Rate, Estimated (eGFR)
*Build Your Own Panel Eligible [?]
|
$49
|
|
|
Description:
This panel comprises a group of tests that provide information on an individual's blood levels of electrolytes, calcium, and glucose as well as renal function, hepatic function, and acid-base balance. The panel is usually ordered as part of a health examination to detect a range of disorders, especially those that may affect the liver or kidneys [1].The results of the panel components are usually evaluated jointly for patterns. The section below outlines the roles of the analytes assessed with this panel [1].Sodium: An electrolyte that plays a central role in maintaining the normal distribution of water and appropriate pressure to assure that substances do not leak from cells and organs. Sodium measurements are useful in the diagnosis and treatment of diseases involving electrolyte imbalance.Potassium: An electrolyte that is essential for proper muscle and nerve function and helps keep the balance of fluids. Potassium measurements are useful in assessing electrolyte balance in the diagnosis and treatment of conditions characterized by low or high blood potassium levels.Chloride: An electrolyte that helps maintain volume, acidity, and electrical neutrality of the body fluids. Chloride measurements are useful in the diagnosis and treatment of electrolyte and metabolic disorders, such as cystic fibrosis and diabetic acidosis.Carbon dioxide (bicarbonate): A type of blood gas used to evaluate the total carbonate buffering system and acid-base balance. Carbon dioxide is generally evaluated with other common electrolytes; the measurements are useful in the diagnosis and treatment of numerous potentially serious disorders associated with changes in body acid-base balance.Glucose: A type of sugar that serves as the body's main energy source. Glucose measurements are useful in the diagnosis of diabetes and low blood sugar.Calcium: A mineral in the body that is essential for nerve, muscle, and heart functions and bone formation. Calcium measurements are useful in the diagnosis of parathyroid disease, some bone disorders, and chronic kidney disease.Blood urea nitrogen (BUN): The principal waste product of protein catabolism. BUN measurements are useful in the diagnosis and treatment of certain kidney and metabolic diseases.Creatinine: A waste product of the muscles. Creatinine measurements are useful in the evaluation of kidney function and in monitoring renal dialysis.Albumin: A protein that keeps fluid from leaking out of the blood and carries hormones, vitamins, and enzymes in the body. Albumin measurements are useful in the monitoring and treatment of numerous diseases involving primarily the liver and kidneys.Total bilirubin: A waste product generated when old red blood cells break down. Bilirubin measurements are useful in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease.Total protein: A sum of albumin and globulins. Protein measurements are useful in the diagnosis of disorders involving the liver, kidneys, or bone marrow.Alkaline phosphatase: An enzyme found mainly in the liver, bones, kidneys, and digestive system. Alkaline phosphatase measurements are useful in the diagnosis of hepatobiliary disorders and bone diseases associated with increased bone formation.Aspartate aminotransferase (AST): An enzyme widely distributed throughout the tissues, with significant amounts present in the heart and liver. AST measurements are useful in the evaluation of liver and heart damage.Alanine aminotransferase (ALT): An enzyme found in highest concentrations in the liver and often measured in conjunction with AST. ALT measurements are useful in the diagnosis and management of certain liver diseases (eg, viral hepatitis and cirrhosis). Very high values may be associated with hepatitis, though some people with hepatitis have ALT values within the reference interval.References1. Rao LV, et al. Laboratory tests. In: Rao LV, eds. Wallach's Interpretation of Diagnostic Tests. Pathways to Arriving at a Clinical Diagnosis. 11th ed. Wolters Kluwer; 2020.
Categories:
Price:
$49
|
Comprehensive Metabolic Profile (CMP) (includes eGFR) with Creatine Kinase
|
$81
|
|
|
Description:
The Comprehensive Metabolic Panel (includes eGFR) measures your blood sugar level, electrolyte and fluid balance, kidney function, and liver function. The Creatine Kinase (CK) test is usually ordered to measure levels of CK in the bloodstream which, when elevated, may indicate a person has suffered a heart attack and has suffered muscle damage to the heart.
Significant deviations from the normal range may require further evaluation by your physician.
Includes:
Comprehensive Metabolic Profile ( includes eGFR ): Albumin, Albumin/Globulin Ratio (calculated), Alkaline Phosphatase, ALT, AST, BUN/Creatinine Ratio (calculated), Calcium, Carbon Dioxide, Chloride, Creatinine with GFR Estimated, Globulin (calculated), Glucose, Potassium, Sodium, Total Bilirubin, Total Protein, Urea Nitrogen
Creatine Kinase (CK), Total, Serum
Patient Instructions:
Patient should fast for 12 hours preceding collection of specimen. Fasting is defined as no consumption of food or beverage other than water for at least 12 hours before testing.
Categories:
Hormones & metabolism,
General wellness,
Price:
$81
|
Comprehensive Metabolic Profile (includes eGFR)
*Build Your Own Panel Eligible [?]
|
$49
|
|
|
Description:
The Comprehensive Metabolic Panel measures your blood sugar level, electrolyte and fluid balance, kidney function, and liver function.
Significant deviations from the normal range may require further evaluation by your physician.
eGFR is intended for patients with stable renal function.
Alternative Name(s): CMP, Metabolic Panels
Includes:
Comprehensive Metabolic Profile (includes eGFR): Albumin, Albumin/Globulin Ratio (calculated), Alkaline Phosphatase, ALT, AST, BUN/Creatinine Ratio (calculated), Calcium, Carbon Dioxide, Chloride, Creatinine with GFR Estimated, Globulin (calculated), Glucose, Potassium, Sodium, Total Bilirubin, Total Protein, Urea Nitrogen
Patient Instructions:
Patient should fast for 12 hours preceding collection of specimen.
Categories:
Hormones & metabolism,
General wellness,
Price:
$49
|
Comprehensive Toxic Metal Panel, 24-Hour Urine
*Build Your Own Panel Eligible [?]
|
$812
|
|
Description:
- Detect toxic metal exposure sources
- Screen for unexplained fatigue causes
- Monitor environmental and workplace exposure risks
Categories:
Price:
$812
|
Comprehensive Wellness Panel
|
$132
|
|
|
Description:
The Comprehensive Wellness Panel is a unisex testing package.
Significant deviations from the normal range may require further evaluation by your physician.
Includes:
Complete Blood Count / CBC (includes Differential and Platelets): WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet Count, MPV and Differential (Absolute and Percent - Neutrophils, Lymphocytes, Monocytes, Eosinophils, and Basophils)
Comprehensive Metabolic Profile ( includes eGFR ): Albumin, Albumin/Globulin Ratio (calculated), Alkaline Phosphatase, ALT, AST, BUN/Creatinine Ratio (calculated), Calcium, Carbon Dioxide, Chloride, Creatinine with GFR Estimated, Globulin (calculated), Glucose, Potassium, Sodium, Total Bilirubin, Total Protein, Urea Nitrogen
Iron, Serum w/ TIBC: Total Iron, Iron Binding Capacity, % Saturation (calculated)
Kidney (Renal) Function Profile: Albumin, BUN/Creatinine Ratio (calculated), Calcium, Carbon Dioxide, Creatinine, Estimated Glomerular Filtration Rate (calculated), Glucose, Phosphate (as Phosphorus), Potassium, Sodium, Urea Nitrogen
Lipid Profile: Cholesterol, total; high-density lipoprotein (HDL) cholesterol; low-density lipoprotein (LDL) cholesterol (calculated); triglycerides; Non-HDL Cholesterol (calculated)
Liver (Hepatic) Function Profile: Total Protein, Albumin, Globulin (calculated), Albumin/Globulin Ratio (calculated), Total Bilirubin, Direct Bilirubin, Indirect Bilirubin (calculated), Alkaline Phosphatase, AST, ALT
Thyroid Profile w/ TSH: T3 Uptake; T4 (Thyroxine), Total; Free T4 Index (T7); Thyroid-Stimulating Hormone (TSH)
Patient Instructions:
Patient should fast for 12 hours preceding collection of specimen. Specimens should be collected in the morning since iron values decrease by 30% during the course of the day and there can be significant interference from lipemia.
Categories:
General wellness,
Price:
$132
|
Congenital Syphilis Screen, FTA (IgG, IgM)
*Build Your Own Panel Eligible [?]
|
$354
|
|
|
Description:
This panel detects both IgG and IgM antibodies to T. pallidum, the causative agent of syphilis.
Categories:
Price:
$354
|
Connexin 26 (GJB2) DNA Sequencing Test
*Build Your Own Panel Eligible [?]
|
$1749
|
|
|
Description:
Detects sequence variants in the GJB2 gene in patients with sensorineural non-syndromic hearing loss.
Categories:
Price:
$1749
|
Connexin 30 (GJB6) DNA Test
*Build Your Own Panel Eligible [?]
|
$876
|
|
|
Description:
Detects deletions in the GJB6 gene in patients with sensorineural non-syndromic hearing loss.
Categories:
Price:
$876
|
Connexin Related Deafness Evaluation
*Build Your Own Panel Eligible [?]
|
$2461
|
|
|
Description:
Detects sequence variants in the GJB2 gene and deletions in the GJB6 gene in patients with sensorineural non-syndromic hearing loss.
Categories:
Price:
$2461
|
Conventional Pap Smear, 2 or More Slides
*Build Your Own Panel Eligible [?]
|
$299
|
|
Description:
- Screen for early cervical cell changes
- Detect abnormal cells before cancer develops
- Protect your long-term reproductive health
Categories:
Price:
$299
|
Copeptin
*Build Your Own Panel Eligible [?]
|
$546
|
|
|
Description:
The Copeptin test is used in the diagnosis of central diabetes insipidus and in the differential diagnosis of central or nephrogenic diabetes insipidus. It is a reliable surrogate marker for arginine vasopressin (AVP).
Categories:
Price:
$546
|
Copper, 24-Hour Urine
*Build Your Own Panel Eligible [?]
|
$396
|
|
Description:
- Measures copper levels in urine.
- Checks copper balance in body.
- Assesses copper-related health conditions.
Includes:
Copper, 24-Hour Urine
Categories:
Price:
$396
|
Copper, Blood
*Build Your Own Panel Eligible [?]
|
$332
|
|
|
Description:
Exposure monitoring/investigation.
Categories:
Price:
$332
|
Copper, Hair
*Build Your Own Panel Eligible [?]
|
$671
|
|
|
Description:
Exposure monitoring/investigation. Not for clinical diagnostic purposes.
Categories:
Price:
$671
|
Copper, Liver Tissue
*Build Your Own Panel Eligible [?]
|
$49
|
|
|
Description:
Diagnosing Wilson disease and primary biliary cirrhosis using liver tissue specimens.
Categories:
Price:
$49
|
Copper, Random Urine
*Build Your Own Panel Eligible [?]
|
$372
|
|
|
Description:
Copper is an essential element that is a cofactor of many enzymes. Copper metabolism is disturbed in Wilson's disease, Menkes disease, primary biliary cirrhosis, and Indian childhood cirrhosis. Urinary copper concentrations are also useful to monitor patients on chelation therapy.
Includes:
Creatinine
Categories:
Allergy blood testing,
Geriatrics/Age Management,
Neurology,
Pediatrics,
Price:
$372
|
Copper, RBC
*Build Your Own Panel Eligible [?]
|
$300
|
|
|
Description:
Copper is an essential element that is a cofactor of many enzymes. Copper metabolism is distributed in Wilson's disease, Menkes disease, primary biliary cirrhosis, and Indian childhood cirrhosis. Copper concentrations increase in acute phase reactions. Copper concentrations are decreased with nephrosis, malabsorption, and malnutrition. Copper concentrations are also useful to monitor patients, especially preterm newborns, on nutritional supplementation. Results of copper are often interpreted together with ceruloplasmin.
Categories:
Price:
$300
|
Copper, Serum or Plasma
*Build Your Own Panel Eligible [?]
|
$84
|
|
|
Description:
Copper is an essential element that is a cofactor of many enzymes. Copper metabolism is disturbed in Wilson's disease, Menkes disease, primary biliary cirrhosis, and Indian childhood cirrhosis. Copper concentrations increase in acute phase reactions and during the third trimester of pregnancy. Copper concentrations are decreased with nephrosis, malabsorption, and malnutrition. Copper concentrations are also useful to monitor patients, especially preterm newborns, on nutritional supplementation. Results of copper are often interpreted together with ceruloplasmin.
Alternative Names(s): Cu, Plasma ; Cu, Serum.
A significant deviation from the normal range may require further evaluation by your physician.
Includes:
Copper, Serum or Plasma
Categories:
Liver diseases,
Price:
$84
|
Coriander/Cilantro (f317) IgE
*Build Your Own Panel Eligible [?]
|
$80
|
|
|
Description:
This test is an allergen-specific IgE antibody test that quantifies an individual’s IgE response to coriander/cilantro. It is an in vitro quantitative assay, which is intended to be used in conjunction with other clinical information to aid in the diagnosis of food allergy [1].
While allergen-specific serum IgE testing is considered comparable to skin testing in many instances, both the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology recognize that allergen-specific serum IgE testing may be preferred in some clinical situations. These include 1) the presence of widespread skin disease, 2) the recent use of antihistamines or other medications that can affect the results of allergy skin tests, 3) uncooperative patients, and 4) medical history suggesting that allergen skin testing would pose a significant risk for a serious allergic reaction [1].
Food-specific IgE tests are extremely sensitive. However, a positive test result only indicates that a patient is IgE sensitized to the food of concern. Many IgE-sensitized patients do not develop any symptoms when this food is ingested. A diagnosis of food allergy should only be made by a trained medical provider, after conducting a thorough clinical evaluation [2,3]. While food-specific IgE test results may contribute to that evaluation, they cannot replace it. In this regard, detection of food-specific IgE in serum provides evidence of IgE sensitization, but a history of clinical reactivity to the food of concern, is required to make a diagnosis of IgE-mediated food allergy. Moreover, several forms of food hypersensitivity are not associated with the presence of food-specific IgE in serum.
More specific information about this allergen can be found at https://www.thermofisher.com/phadia/wo/en/resources/allergen-encyclopedia/whole-allergens.html?key=f317
References
1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(suppl 3):S1-S148.
2. Sampson HA et al. J Allergy Clin Immunol. 2014;134(5):1016-1025.
3. Boyce JA, et al. J Allergy Clin Immunol. 2010;126(6 suppl):S1-S58.
Alternative names: ImmunoCAP®
Categories:
Allergy blood testing,
Price:
$80
|
Corn, Grass (g202) IgE
*Build Your Own Panel Eligible [?]
|
$49
|
|
|
Description:
This test quantifies an individual's IgE response to corn as a grass (corn pollen). Allergen-specific serum IgE testing is considered comparable to skin testing and may be preferred in some clinical situations. However, a positive test result only indicates that a patient is sensitized to the allergen of concern. Many IgE-sensitized individuals do not develop any symptoms when exposed to the allergen. A diagnosis of allergy should only be made by a trained medical provider after conducting a thorough clinical evaluation [1].More specific information about this allergen can be found on the following website: https://www.thermofisher.com/phadia/us/en/resources/allergen-encyclopedia.htmlReference 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.
Categories:
Price:
$49
|
Corn IgG4
*Build Your Own Panel Eligible [?]
|
$254
|
|
Description:
- Detect possible corn food sensitivity
- Screen digestive discomfort after eating
- Track energy levels and skin issues
Categories:
Price:
$254
|
Corn Smut, Tilletia tritici (m201), IgE
*Build Your Own Panel Eligible [?]
|
$49
|
|
|
Description:
This allergen-specific IgE antibody test quantifies an individual’s IgE response to corn smut. It is an in vitro quantitative assay that is intended to be used in conjunction with other clinical information to aid in the diagnosis of allergic diseases [1]. While allergen-specific serum IgE testing is considered comparable to skin testing in many instances, both the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology recognize that allergen-specific serum IgE testing may be preferred in some clinical situations. These include 1) the presence of widespread skin disease, 2) the recent use of antihistamines or other medications that can affect the results of allergy skin tests, 3) uncooperative patients, and 4) medical history suggesting that allergen skin testing would pose a significant risk for a serious allergic reaction [1]. A definitive clinical diagnosis of allergy should not be based on the results of any single diagnostic method, but should be made by a trained healthcare provider after all clinical and laboratory findings have been evaluated. More specific information about this allergen can be found at http://www.phadia.com/en/Products/Allergy-testing-products/ImmunoCAP-Allergen-Information/Molds-and-other-Microorganisms/Allergens/Tilletia-triticiUstilago/ Reference 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(Suppl 3):S1-S148.
Categories:
Price:
$49
|
Corticosterone
*Build Your Own Panel Eligible [?]
|
$410
|
|
|
Description:
Measurement of corticosterone may help confirm the diagnosis of the very rare aldosterone deficiency disorder, corticosterone methyl oxidase (18-hydroxylase) enzyme deficiency where the ratio of corticosterone to 18-hydroxycosticosterone may be increased.
Categories:
Price:
$410
|
Cortisol, 2 Specimens
*Build Your Own Panel Eligible [?]
|
$60
|
|
|
Description:
Cortisol is increased in Cushing's disease and decreased in Addison's disease (adrenal insufficiency).
Categories:
Price:
$60
|
Cortisol, 3 Specimens
*Build Your Own Panel Eligible [?]
|
$91
|
|
|
Description:
Cortisol is increased in Cushing's disease and decreased in Addison's disease (adrenal insufficiency).
Categories:
Price:
$91
|
Cortisol, AM
*Build Your Own Panel Eligible [?]
|
$54
|
|
|
Description:
Cortisol is the major adrenal glucocorticoid steroid hormone, and is normally under feedback control by pituitary ACTH and the hypothalamus.
Causes of low cortisol include pituitary destruction or failure, with resultant loss of ACTH to stimulate the adrenal, and metabolic errors or destruction of the adrenal gland itself (adrenogenital syndromes, tuberculosis, histoplasmosis). The diagnosis of hypoadrenalism generally requires confirmation with ACTH stimulation, due to the circadian rhythms of cortisol and other factors. Causes of increased cortisol, which may present initially simply as loss of normal diurnal variation, include pituitary overproduction of ACTH, production of ACTH by a tumor (notably oat cell cancers), and adrenal adenomas.
A significant deviation from the normal range may require further evaluation by your physician.
Includes:
Cortisol, AM
Patient Instructions:
Specimen should be collected between 7 AM and 9 AM. Assay is not recommended when patient is receiving prednisone/prednisolone therapy due to cross reactivity with the antibody used in this assay.
Categories:
Hormones & metabolism,
Price:
$54
|
Cortisol, Free, 24-Hour Urine with Creatinine, LC/MS/MS
*Build Your Own Panel Eligible [?]
|
$332
|
|
|
Description:
Measures the amount of free (unbound) cortisol excreted in urine over a 24-hour period, along with creatinine to verify collection adequacy. Using liquid chromatography-tandem mass spectrometry (LC/MS/MS) for high accuracy, this test is primarily used to help evaluate for excess cortisol production, as seen in Cushing's syndrome. The 24-hour collection captures total daily cortisol output, smoothing out the normal day-to-night fluctuations that a single blood draw would miss. Results are often reported both as a total amount and as a ratio to creatinine.
Categories:
Hormones & metabolism,
Price:
$332
|
Cortisol, Free And Cortisone, 24 Hour Urine with Creatinine
*Build Your Own Panel Eligible [?]
|
$752
|
|
|
Description:
Urinary free cortisol is useful in the detection of patients with Cushing's syndrome for whom free cortisol concentrations are elevated
Categories:
Price:
$752
|
Cortisol, Free and Total, LC/MS
*Build Your Own Panel Eligible [?]
|
$488
|
|
|
Description:
Free cortisol is useful in the detection of patients with Cushing's syndrome for whom free cortisol concentrations are elevated.
Categories:
Price:
$488
|
Cortisol, Free, LC/MS/MS, Second Void Urine
*Build Your Own Panel Eligible [?]
|
$341
|
|
|
Description:
Urinary free cortisol is useful in the detection of patients with Cushing's syndrome for whom free cortisol concentrations are elevated.
Categories:
Price:
$341
|
Cortisol, Free, LC/MS, Serum
*Build Your Own Panel Eligible [?]
|
$374
|
|
|
Description:
Free cortisol is useful in the detection of patients with Cushing's syndrome for whom free cortisol concentrations are elevated.
Categories:
Price:
$374
|
Cortisol, LC/MS, Saliva
*Build Your Own Panel Eligible [?]
|
$354
|
|
|
Description:
Salivary cortisol level, particularly late-night salivary cortisol (LNSC) level, is useful in screening for endogenous Cushing syndrome. Two or more positive results of LNSC tests may be used to confirm Cushing syndrome. LNSC measurement may also be used to monitor for recurrence of Cushing disease [1].Normally, the secretion of cortisol has a circadian rhythm. Patients with Cushing syndrome often lose the late-night circadian nadir. Therefore, an elevated LNSC level may provide initial evidence for Cushing syndrome. Two or more positive results of LNSC tests may establish the diagnosis of Cushing syndrome if non-neoplastic hypercortisolism (pseudo-Cushing syndrome) is excluded. Because saliva is convenient to collect, LNSC testing is especially useful for individuals who need to provide multiple specimens over time for the evaluation of cyclic Cushing syndrome [1].Annual LNSC testing is recommended to monitor for the recurrence of Cushing disease after pituitary surgery. LNSC testing may also be used in assessing treatment outcomes in patients receiving medical therapy for Cushing disease [1].Non-neoplastic hypercortisolism caused by obesity, psychiatric disorders, alcohol use disorder, and polycystic ovary syndrome may increase LNSC levels. LNSC testing should not be used to screen for Cushing syndrome in individuals without normal day and night cycles. LNSC testing has low sensitivity in patients with adrenal tumors [1].Other tests, such as urinary free cortisol (test code 14534) and dexamethasone suppression test (test code 6921), may also be used to screen for Cushing syndrome. Choice of tests should be individualized based upon clinical scenarios [1].The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.Reference1. Fleseriu M, et al. Lancet Diabetes Endocrinol. 2021;9(12):847-875.
Categories:
Price:
$354
|
Cortisol, LC/MS, Saliva, 2 Samples
*Build Your Own Panel Eligible [?]
|
$397
|
|
|
Description:
Salivary cortisol level, particularly late-night salivary cortisol (LNSC) level, is useful in screening for endogenous Cushing syndrome. Two or more positive results of LNSC tests may be used to confirm Cushing syndrome. LNSC measurement may also be used to monitor for recurrence of Cushing disease [1].Normally, the secretion of cortisol has a circadian rhythm. Patients with Cushing syndrome often lose the late-night circadian nadir. Therefore, an elevated LNSC level may provide initial evidence for Cushing syndrome. Two or more positive results of LNSC tests may establish the diagnosis of Cushing syndrome if non-neoplastic hypercortisolism (pseudo-Cushing syndrome) is excluded. Because saliva is convenient to collect, LNSC testing is especially useful for individuals who need to provide multiple specimens over time for the evaluation of cyclic Cushing syndrome [1].Annual LNSC testing is recommended to monitor for the recurrence of Cushing disease after pituitary surgery. LNSC testing may also be used in assessing treatment outcomes in patients receiving medical therapy for Cushing disease [1].Non-neoplastic hypercortisolism caused by obesity, psychiatric disorders, alcohol use disorder, and polycystic ovary syndrome may increase LNSC levels. LNSC testing should not be used to screen for Cushing syndrome in individuals without normal day and night cycles. LNSC testing has low sensitivity in patients with adrenal tumors [1].Other tests, such as urinary free cortisol (test code 14534) and dexamethasone suppression test (test code 6921), may also be used to screen for Cushing syndrome. Choice of tests should be individualized based upon clinical scenarios [1].The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.Reference1. Fleseriu M, et al. Lancet Diabetes Endocrinol. 2021;9(12):847-875.
Categories:
Price:
$397
|
Cortisol, LC/MS, Saliva, 3 Samples
*Build Your Own Panel Eligible [?]
|
$522
|
|
|
Description:
Salivary cortisol level, particularly late-night salivary cortisol (LNSC) level, is useful in screening for endogenous Cushing syndrome. Two or more positive results of LNSC tests may be used to confirm Cushing syndrome. LNSC measurement may also be used to monitor for recurrence of Cushing disease [1].Normally, the secretion of cortisol has a circadian rhythm. Patients with Cushing syndrome often lose the late-night circadian nadir. Therefore, an elevated LNSC level may provide initial evidence for Cushing syndrome. Two or more positive results of LNSC tests may establish the diagnosis of Cushing syndrome if non-neoplastic hypercortisolism (pseudo-Cushing syndrome) is excluded. Because saliva is convenient to collect, LNSC testing is especially useful for individuals who need to provide multiple specimens over time for the evaluation of cyclic Cushing syndrome [1].Annual LNSC testing is recommended to monitor for the recurrence of Cushing disease after pituitary surgery. LNSC testing may also be used in assessing treatment outcomes in patients receiving medical therapy for Cushing disease [1].Non-neoplastic hypercortisolism caused by obesity, psychiatric disorders, alcohol use disorder, and polycystic ovary syndrome may increase LNSC levels. LNSC testing should not be used to screen for Cushing syndrome in individuals without normal day and night cycles. LNSC testing has low sensitivity in patients with adrenal tumors [1].Other tests, such as urinary free cortisol (test code 14534) and dexamethasone suppression test (test code 6921), may also be used to screen for Cushing syndrome. Choice of tests should be individualized based upon clinical scenarios [1].The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.Reference1. Fleseriu M, et al. Lancet Diabetes Endocrinol. 2021;9(12):847-875.
Categories:
Price:
$522
|
Cortisol, P.M.
*Build Your Own Panel Eligible [?]
|
$49
|
|
|
Description:
Cortisol is increased in Cushing's Disease and decreased in Addison's Disease (adrenal insufficiency).
Categories:
Price:
$49
|
Cortisol Response to ACTH Stimulation, Serum
*Build Your Own Panel Eligible [?]
|
$49
|
|
|
Description:
The cortisol response to infusion of synthetic ACTH is useful in diagnosing patients with adrenal insufficiency (Addison's disease).
Categories:
Price:
$49
|
Cortisol saliva test 4-tube
*Build Your Own Panel Eligible [?]
|
$359
|
|
Description:
- Measures stress hormone levels daily.
- Checks cortisol at four times daily.
- Monitors body's stress response pattern.
Patient Instructions:
No fasting needed.
Categories:
Price:
$359
|
Cortisol, Total
*Build Your Own Panel Eligible [?]
|
$59
|
|
|
Description:
Measures the level of cortisol, crucial for managing stress, regulating metabolism & maintaining overall health.
Too much cortisol can throw off your hormone production and lead to all sorts of things, including unwanted weight gain.
It's like peeking into your body's stress response system, ensuring it's in balance and functioning smoothly so you can feel happy and calm.
Includes:
Cortisol, Total
Patient Instructions:
Cortisol, Total assay not recommended when patient is on prednisone/prednisolone therapy due to cross reactivity with the antibody used in this assay
Categories:
Hormones & metabolism,
Fitness, nutrition, anti-aging,
Price:
$59
|
Cortisol, Total, LC/MS
*Build Your Own Panel Eligible [?]
|
$354
|
|
|
Description:
Total cortisol concentrations are decreased in Addison's Disease and increased in Cushing's Disease and in other conditions of glucocorticoid excess.
Categories:
Price:
$354
|
Cortisone, 24-Hour Urine
*Build Your Own Panel Eligible [?]
|
$504
|
|
|
Description:
This test, when used in conjunction with the measurement of 24-hour urine cortisol, may help in the diagnosis of apparent mineralocorticoid excess (AME) syndrome [1].Cortisone is an inactive metabolite of cortisol converted by 11-beta-hydroxysteroid dehydrogenase type 2 (11-beta-HSD2) in the kidney. In patients with AME syndrome, deficiency of 11-beta-HSD2 impairs the deactivation of cortisol to cortisone. Consequently, accumulated cortisol activates mineralocorticoid receptors and leads to clinical manifestations resembling primary aldosteronism. Patients with AME typically present with low-renin hypertension, hypokalemia, and metabolic alkalosis. Similarly, ingestion of certain compounds that inhibit 11-beta-HSD2 activity, such as glycyrrhetinic acid (in licorice), carbenoxolone, and phthalates, may also reduce the conversion of cortisol to cortisone. Therefore, a high cortisol-to-cortisone ratio measured in 24-hour urine may help in identifying disorders caused by impaired activity of 11-beta-HSD2 [1, 2].This test should be used in conjunction with 24-hour urine cortisol testing to evaluate the activity of 11-beta-HSD2 [1]. High serum cortisol-to-cortisone ratios in addition to low cortisone levels may also be helpful in the diagnosis of AME syndrome [2].The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.References1. Young WF, Jr., et al. Endocrine Reviews. 2017;38(2):103-122.2. Carvajal CA, et al. J Clin Endocrinol Metab. 2020;105(4):dgz315.
Categories:
Price:
$504
|
Cortisone, Serum
*Build Your Own Panel Eligible [?]
|
$410
|
|
|
Description:
Measurement of both Free Cortisol and Cortisone are useful in diagnosing patients with low-renin hypertension caused by apparent mineralocorticoid excess. This may be due to either an inherited defect in 11HSDB2 enzyme or an acquired inhibitor of the enzyme by such compounds as glycyrrhizic acid, a component of natural licorice.
Categories:
Price:
$410
|
Cotton, Crude Fibers (o1) IgE
*Build Your Own Panel Eligible [?]
|
$49
|
|
|
Description:
This test detects the presence of specific IgE against crude fibers from cotton. A positive test only indicates that a person is sensitized and potentially allergic to this allergen. A diagnosis of allergy requires clinical signs and symptoms that appear to be associated with exposure to the allergen in addition to the detection of markers of IgE sensitization [1].More specific information about this allergen can be found on the following website: https://www.thermofisher.com/phadia/us/en/resources/allergen-encyclopedia.htmlReference1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.
Categories:
Price:
$49
|
Cotton Seed (k83) IgE
*Build Your Own Panel Eligible [?]
|
$49
|
|
|
Description:
This test detects the presence of specific IgE against cotton seeds. A positive test only indicates that a person is sensitized and potentially allergic to this allergen. A diagnosis of allergy requires clinical signs and symptoms that appear to be associated with exposure to the allergen in addition to the detection of markers of IgE sensitization [1].More specific information about this allergen can be found on the following website: https://www.thermofisher.com/phadia/us/en/resources/allergen-encyclopedia.htmlReference1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.
Categories:
Price:
$49
|