Factor H (B1H) Level
*Build Your Own Panel Eligible [?]
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$444
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Description:
- Check immune system regulation levels
- Monitor kidney health risk factors
- Track recurrent infection related causes
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Price:
$444
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Factor II Activity, Clotting
*Build Your Own Panel Eligible [?]
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$476
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Description:
Factor II Activity, Clotting - The Factor II Activity clotting assay provides a quantitative level of Factor II (also known as Prothrombin) activity. Factor II/Prothrombin is essential for normal hemostasis and deficiencies are associated with increased bleeding risk. As a vitamin K- dependent clotting factor, decreased levels are observed with vitamin K antagonists (eg. warfarin therapy) and vitamin K deficiency. Deficiencies may also occur with hepatic dysfunction or as a result of inhibitor development. Antibodies to prothrombin can occur in patients with anti- phospholipid antibodies and can cause significant clinical bleeding; however, because these antibodies bind to a nonactive portion of the molecule, increased clearance occurs, so that a deficiency rather than an inhibitor is detected. Congenital Factor II deficiency is extremely rare. Anticoagulant interference: if not clinically contraindicated, avoid warfarin therapy for approximately 2 weeks before testing. Direct Xa or thrombin inhibitor therapy may cause falsely low levels (avoid for approximately 2-3 days before testing if not clinically contraindicated. The Factor II Activity, Clotting assay IS NOT intended to identify the Prothrombin 20210G>A Gene Mutation, which is associated with the increased thrombotic risk.
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Price:
$476
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Factor IX Activity and Human Inhibitor
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$788
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Description:
Factor IX Human Inhibitor provides a quantitative determination of inhibitors. This aids in developing treatment strategies for patients with hemophilia.
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Price:
$788
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Factor IX Activity, Clotting
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$476
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Description:
This test is useful to evaluate a prolonged aPTT. Deficiency of Factor IX can be seen with congenital deficiency (Hemophilia B, X-linked disorder) which affects approximately 1 in 25,000 males. As a vitamin K-dependent clotting factor, decreased levels are also observed with vitamin K antagonists (eg. warfarin therapy) and vitamin K deficiency. Deficiencies may be seen with liver disease, disseminated intravascular coagulation (DIC) and in other consumptive coagulopathies. Anticoagulant interference: Expected impact by therapeutic levels (potential interference depends upon drug concentration): Warfarin: decrease; Heparin (UFH or LMWH): no effect to inhibitor pattern; Dabigatran or Argatroban (Thrombin Inhibitors): no effect to inhibitor pattern; Rivaroxaban, Apixaban, Edoxaban (Factor Xa Inhibitors): no effect to inhibitor pattern. Other limitations: Lupus anticoagulant may cause falsely low to inhibitor pattern. Factor specific inhibitors (autoantibodies or in response to replacement therapies) may cause falsely low or inhibitor patterns.
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Price:
$476
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Factor IX Antigen
*Build Your Own Panel Eligible [?]
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$476
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Description:
The laboratory diagnosis of factor IX deficiency typically involves quantitative determinations of functional activity of factor IX. An ELISA for factor IX antigen may be used in conjunction with functional assays in the area of gene therapy, assessment of factor IX concentrates, determination of carrier status as well as distinguishing those patients with cross-reactive material (i.e. low functional activity but near normal antigen levels of factor IX).
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Price:
$476
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Factor V Activity and Human Inhibitor
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$733
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Description:
This panel quantifies coagulation factor V activity and inhibitors to factor V and may be used to support the diagnosis of factor V deficiency as a result of inhibitor development. Coagulation factor V plays an essential role in hemostasis by promoting thrombin generation at the activated platelet surface. Deficiency of factor V leads to a rare bleeding disorder and can be congenital or acquired. Congenital factor V deficiency is caused by pathogenic variants of the F5 gene, while acquired factor V deficiency can be caused by liver disease, consumptive coagulopathies, disseminated intravascular coagulation, or inhibitors (autoantibodies or alloantibodies) that interfere with factor V activity. Inhibition of factor V activity secondary to antibody development is a rare occurrence and may be induced by chemical agents, drugs, or surgical procedures using bovine thrombin [1]. Patients with inhibitors to factor V usually have prolonged prothrombin time (PT) and activated partial thromboplastin time (aPTT), low factor V activity levels, and a normal thrombin time. Factor V inhibitors are measured using a Bethesda assay and are reported in Bethesda titer units (BU). Quantification of factor V inhibitors may inform treatment decisions for acquired factor V deficiency and help monitor inhibitor suppression therapy [1].The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.Reference1. Tabibian S, et al. Semin Thromb Hemost. 2019;45(5):523-543.
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Price:
$733
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Factor V Activity, Clotting
*Build Your Own Panel Eligible [?]
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$476
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Description:
This test measures coagulation factor V activity and may be used to help determine the cause of a prolonged prothrombin time (PT) or activated partial thromboplastin time (aPTT).Coagulation factor V plays an essential role in hemostasis by promoting thrombin generation at the activated platelet surface. Deficiency of factor V leads to a rare bleeding disorder and can be congenital or acquired. Congenital factor V deficiency, also known as parahemophilia or Owren's disease, has an incidence of 1 per one million [1] and is caused by pathogenic variants of the F5 gene, which encodes factor V. Acquired factor V deficiency can be caused by liver disease, consumptive coagulopathies, disseminated intravascular coagulation, or inhibitors (autoantibodies or alloantibodies) that interfere with factor V activity. Inhibitors to factor V may be induced by chemical agents, drugs, or surgical procedures using bovine thrombin [1].Factor activity assays, including factor V activity assay, are usually indicated in patients with bleeding symptoms and prolonged PT and aPTT [1].The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.Reference1. Tabibian S, et al. Semin Thromb Hemost. 2019;45(5):523-543.
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Price:
$476
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Factor V HR2 Allele DNA Mutation Analysis
*Build Your Own Panel Eligible [?]
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$548
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Description:
Factor V HR2 Allele, DNA Mutation Analysis is useful in patients who are carriers of Factor V Mutation (Leiden). Coinheritance of Factor V Mutation (Leiden) is associated with a 3-4-fold increased risk of venous thrombosis compared to inheritance of Factor V Mutation (Leiden) alone.
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Price:
$548
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Factor VII Activity, Clotting
*Build Your Own Panel Eligible [?]
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$476
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Description:
Test is useful to evaluate a prolonged PT. Deficiency is associated with bleeding risk.
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Price:
$476
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Factor VIII Activity, Chromogenic
*Build Your Own Panel Eligible [?]
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$371
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Description:
Preferred test in patients with Lupus anticoagulant, on heparin or direct thrombin inhibitors, or on Factor VIII concentrates.
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Price:
$371
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Factor VIII Activity, Clotting with Reflex to Chromogenic Method
*Build Your Own Panel Eligible [?]
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$404
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Description:
In the presence of a suspected lupus anticoagulant, the one-stage appt based assay may yield false low FVIII values consistent with "haemophilia" whereas the chromogenic assay avoids lupus anticoagulant interference and yields accurate FVIII results.
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Price:
$404
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Factor VIII Antigen
*Build Your Own Panel Eligible [?]
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$468
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Description:
An ELISA for Factor VIII antigen may be used in conjunction with the functional assays in the assessment of Factor VIII replacement therapies, assessment of carrier status, as well as to distinguish those patients that may be deemed cross-reactive material (CRM) positive.
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Price:
$468
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Factor VIII Inhibitor, Chromogenic
*Build Your Own Panel Eligible [?]
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$540
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Description:
Patients with severe and moderate hemophilia often need specific substitution therapy with plasma derived or recombinant Factor VIII concentrates. About 15-35% of hemophiliacs treated with FVIII concentrates develop specific alloantibodies against human FVIII (inhibitors). The development of functionally inhibiting alloantibodies in hemophilia represents a serious clinical problem. In some patients, infusion of excessive amounts of Factor VIII may be utilized to overcome the antibody. However, this may result in an increased titer of the inhibitor leaving the patient unresponsive to further treatment. Therefore, detection and quantitation of inhibitors is of great importance in the care of these patients.In non-hemophiliacs, development of circulating FVIII inhibitors can lead to acquired hemophilia, a rare bleeding disorder with an incidence of 1 per 106 persons per year. Acquired hemophilia can develop in patients with immunologic disorders such as rheumatoid arthritis, postpartum women, and in older individuals with no underlying disease.Inhibitors to Factor VIII have been denoted as high- or low-responses based on the amnestic response of the antibody to antigenic challenge. Alloantibodies, which demonstrate an increase in titer, have been termed high-response inhibitors while those that do not have been termed low-response inhibitors. An antibody which is persistently 5 Bethesda units per mL (BU/mL) despite repeated challenge with substitution factor concentrate should be termed as low-response inhibitor, whereas the term high-response inhibitor should be applied to cases where the inhibitory activities have been >5 BU/mL at any time.Factor VIII Activity and Factor VIII Inhibitor give a quantitative value for inhibitor activity in the determination of treatment options and the Nijmegen gives a more accurate value to low titer inhibitors which impacts treatment options.Unlike other tests which use human coagulation Factors IX and X, the reagents used in this test contain bovine Factors IX and X. In patients being treated with Emicizumab (Hemlibra), the drug will interact with activated Factor IX and Factor X, which will result in Factor X being activated in the absence of Factor VIII activity. This could result in a false negative result, as even in the presence of Factor VIII inhibitors Emicizumab will cause the coagulation cascade to proceed. Emicizumab does not interact with bovine factors therefore there is no risk of Emicizumab interference with this test.
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Price:
$540
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Factor VIII Inhibitor Panel
*Build Your Own Panel Eligible [?]
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$868
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Description:
The presence of alloantibodies against factor VIII activity is a complication of treatment in hemophilia A, while the presence of autoantibodies may develop spontaneously in patients with acquired Factor VIII-C deficiency. The presence of Factor VIII inhibitor may lead to the neutralization (inactivation) of transfused or endogenous Factor VIII activity. The detection and magnitude of Factor VIII inhibitor is of great importance in the care of these patients. Factor VIII inhibitor Chromogenic assay provides a quick method for the detection of Factor VIII inhibitor with less sample volume.
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Price:
$868
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Factor VII R353Q Mutation Analysis
*Build Your Own Panel Eligible [?]
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$681
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Description:
Factor VII is a serine protease found in plasma and is one of the vitamin K-dependent coagulation factors, along with prothrombin (factor II), factors IX and X, and proteins C and S. Factor VII is synthesized principally in the liver and is secreted as a single-chain glycoprotein of apparent M, 48,000. Cleavage of human factor VII to factor VIIa, a two-chain form held together by disulfide bonds, results in a 20-to 25-fold increase in enzyme activity. This cleavage can be affected by a number of activated coagulation factors, including factors XIIa, Xa, IXa, and thrombin. In the presence of tissue factor and calcium ions, factor VIIa converts factor X to factor Xa in the initiating reaction of the extrinsic coagulation pathway. The R353Q allele may confer protection against thrombosis.
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Price:
$681
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Factor V (Leiden) Mutation Analysis
*Build Your Own Panel Eligible [?]
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$578
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Description:
This test checks for a specific mutation in the Factor V gene, which can increase the risk of developing abnormal blood clots. People with this mutation may have a higher tendency for clotting disorders.
Categories:
Genetic testing,
Price:
$578
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Factor V (Leiden) Mutation Analysis with Reflex to HR2 Mutation Analysis
*Build Your Own Panel Eligible [?]
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$600
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Description:
This test detects the factor V Leiden variant, the most common cause of inherited thrombophilia; it may be used to evaluate individuals with a strong personal or family history of venous thromboembolism (VTE) and inform treatment or preventive decisions [1]. Testing the factor V R2 variant in factor V Leiden heterozygous patients helps assess additional risk of VTE.Factor V Leiden refers to the c.1691G>A variant in the FV gene, which encodes coagulation factor V. This variant results in resistance to factor V protein degradation by activated protein C and increases the risk of VTE 6 to 8 fold in heterozygous carriers and 80 fold in homozygous carriers [1]. The mean age of symptom onset is 31 to 44 years, but some heterozygous carriers can be asymptomatic [2]. In the United States, Factor V Leiden is most prevalent in White individuals, with an estimated frequency of 5% [1].Factor V Leiden testing may be indicated in clinical scenarios where results can help guide clinical decisions for the patient and family members. These clinical scenarios include first VTE developed under 50 years of age, VTE at an unusual site (eg, cerebral veins), recurrent VTE, a strong family history of VTE, and low activated protein C resistance activity [1].Routine testing for factor V Leiden is not recommended for prenatal carrier screening, newborn screening, or individuals taking an oral contraceptive [2]. A negative result of this test does not rule out inherited thrombophilia. Other than factor V Leiden, variants in the genes that encode coagulation factor II, protein C, protein S, and antithrombin can also cause inherited thrombophilia.If the factor V Leiden result is heterozygous, the R2 variant (c.3980A>G) in the FV gene will be tested. Although the R2 allele alone does not increase the risk of VTE, coinheritance of factor V R2 and factor V Leiden is associated with a 3- to 4-fold increase in risk of VTE [3].The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.References1. Zhang S, et al. Genet Med. 2018;20(12):1489-1498.2. Vnencak-Jones CL, et al. Genetics. In: Rifai R, et al, eds. Tietz Textbook of Laboratory Medicine. 7th ed. Elsevier Inc; 2022.3. Faioni EM, et al. Blood. 1999;94(9):3062-3066.
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Price:
$600
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Factor X Activity, Chromogenic
*Build Your Own Panel Eligible [?]
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$419
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Description:
To assess Factor X chromogenic activity in plasma. This assay may help in monitoring OAC patients with prolonged pro-times such as Warfarin patients with lupus inhibitor.
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Price:
$419
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Factor X Activity, Clotting
*Build Your Own Panel Eligible [?]
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$476
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Description:
The Factor X Activity clotting assay provides a quantitative level of Factor X activity. Factor X is essential for normal hemostasis and deficiencies are associated with increased bleeding risk. As a vitamin K- dependent clotting factor, decreased levels are observed with vitamin K antagonists (eg. warfarin therapy) and vitamin K deficiency. Deficiencies may also occur with hepatic dysfunction, disseminated intravascular coagulopathy (DIC), as a result of inhibitor development, amyloidosis, and with certain malignancies. Congenital Factor X deficiency is extremely rare. Anticoagulant interference: If not clinically contraindicated, avoid warfarin therapy for approximately 2 weeks before testing. Because of the possibility of falsely low levels with direct thrombin inhibitors (eg. Argatroban and Dabigatran) and Factor Xa inhibitors (Rivaroxaban, Apixaban, Edoxaban), these drugs should be avoided, if not clinically contraindicated, for approximately 2-3 days before testing.
Categories:
Price:
$476
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Factor XI Activity and Human Inhibitor
*Build Your Own Panel Eligible [?]
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$868
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Description:
Factor XI Inactivator assay issued to quantitate inhibitor present in patient sample. The Bethesda assay is the most common test for determination of circulating FXI inhibitor in plasma.
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Price:
$868
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Factor XI Activity, Clotting
*Build Your Own Panel Eligible [?]
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$476
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Description:
This test is useful to evaluate a prolonged aPTT. Deficiency Factor XI is most common among those with Ashkenazi Jewish heritage. It should be noted that the risk for clinical bleeding does not correlate with the degree of deficiency. Occasionally patients with decreased Factor XI activity may show an inhibitor pattern on testing. This may be due to a lupus anticoagulant, a factor specific inhibitor, or a specific Factor XI inhibitor. The possibilities can be evaluated by mixing studies and/or specific testing for a lupus anticoagulant. Anticoagulant interference: Expected impact by therapeutic levels (potential interference depends upon drug concentration): Warfarin: no effect; Heparin (UFH or LMWH): no effect to inhibitor pattern; Dabigatran or Argatroban (Direct Thrombin Inhibitors): no effect to inhibitor pattern; Rivaroxaban or Apixaban (Factor Xa Inhibitors): no effect to inhibitor pattern. Because of the possibility of falsely low levels, these drugs should be avoided, if not clinically contraindicated, for approximately 2-3 days before testing.
Categories:
Price:
$476
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Factor XII Activity, Clotting
*Build Your Own Panel Eligible [?]
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$476
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Description:
The Factor XII Activity clotting assay provides a quantitative level of Factor XII activity. Deficiency of Factor XII is not associated with a bleeding or thrombotic risk. In the absence of a lupus anticoagulant, Factor XII deficiency should be suspected when an isolated prolonged aPTT occurs in a non-bleeding patient. Direct thrombin or factor Xa inhibitors may yield falsely low results and/or inhibitor pattern with testing. If not clinically contraindicated, avoid for approximately 2-3 days before testing. Vitamin K antagonists (eg. warfarin therapy) have no effect on levels.
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Price:
$476
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Factor XIII, Functional
*Build Your Own Panel Eligible [?]
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$369
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Description:
Low Factor XIII levels, i.e., <15%, may cause a bleeding disorder and levels
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Price:
$369
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Factor XII Inhibitor Panel
*Build Your Own Panel Eligible [?]
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$358
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Description:
- Check for unexplained clotting problems
- Screen abnormal clotting test results
- Assess unusual bleeding or bruising causes
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Price:
$358
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Factor XIII V34L Mutation Analysis
*Build Your Own Panel Eligible [?]
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$681
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Description:
A large meta-analysis provided evidence that the FXIII Val34Leu variant (NT_034880.3, 6258794) has a small, but significant protective effect against VTE. The variant is common in White populations, with a frequency of approximately 0.25-0.30. However, the frequency varies among ethnic groups, with the lowest (0.1) in Japanese and the highest (0.40) in Pima Indians. The biochemical consequences of the FXIII Val34Leu variant are not well understood. The FXIII Val34Leu variant does not result in a change in the plasma concentration of FXIII, but the amino acid change may modify FXIII activity. Activation of FXIIIA by thrombin was found to progress two to threefold more rapidly in plasma of FXIII Val34Leu variant carriers. This action has an effect on clot stability since the catalytic efficiency of thrombin-induced cleavage of FXIIIA alters the structure of the cross-linked fibrin such that fibrin fully crossed-linked by FXIII Val34Leu product has a finer structure with thinner fibers and smaller pores. Lateral aggregation of fibrin fibers is impaired.
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Price:
$681
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Factor XI Mutation Analysis (Ashkenazi Jewish)
*Build Your Own Panel Eligible [?]
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$763
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Description:
This test identifies Ashkenazi-Jewish individuals who are at risk of having prolonged bleeding incidents (especially during surgery) due to mutations in the factor XI gene.
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Price:
$763
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False Ragweed (w4) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This test quantifies an individual's IgE response to false ragweed. Allergen-specific serum IgE testing is considered comparable to skin testing and may be preferred in some clinical situations. However, a positive test result only indicates that a patient is sensitized to the allergen of concern. Many IgE-sensitized individuals do not develop any symptoms when exposed to the allergen. A diagnosis of allergy should only be made by a trained medical provider after conducting a thorough clinical evaluation [1].More specific information about this allergen can be found on the following website: https://www.thermofisher.com/phadia/us/en/resources/allergen-encyclopedia.htmlReference 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148
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Price:
$49
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Familial Dysautonomia Mutation Analysis
*Build Your Own Panel Eligible [?]
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$584
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Description:
Familial Dysautonomia (FD, affecting the autonomic nervous system) has a carrier rate of 1 in 40 in Ashkenazi Jewish individuals, This assay detects 99.5% of FD mutations in that population.
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Price:
$584
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Familial Hypercholesterolemia (FH) Panel
*Build Your Own Panel Eligible [?]
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$4151
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Description:
Familial hypercholesterolemia (FH) is characterized by high levels of LDL cholesterol (LDL-C). Elevated levels of LDL-C cause an increased risk for premature coronary artery disease, which can result in myocardial infarction. Individuals with FH may also develop visible lipid deposits in the tendons (tendon xanthoma) or eyes (corneal arcus). The LDLR, APOB, and PCSK9 genes are associated with familial hypercholesterolemia. This test includes comprehensive analysis of these three genes.
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Price:
$4151
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Familial Hyperinsulinism
*Build Your Own Panel Eligible [?]
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$788
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Description:
The familial hyperinsulinism (FH) test offers molecular detection of two common pathogenic variants in the ABCC8 gene, IVS32-9G>A (c.3989-9G>A) and F1387del (c.4160_4162delTCT), which account for approximately 90% of Ashkenazi-Jewish FH pathogenic variants. FH is an autosomal recessive disorder characterized by an inability to suppress insulin production that results in hypoglycemia (low blood sugar).
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Price:
$788
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Familial Mediterranean Fever Mutation Analysis
*Build Your Own Panel Eligible [?]
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$1040
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Description:
1. To identify disease-causing mutations in individuals affected with Familial Mediterranean Fever. 2. To identify carriers in high risk ethnic groups or people with a positive family history. 3. Prenatal diagnosis of Familial Mediterranean Fever.
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Price:
$1040
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Fanconi Anemia DNA Mutation Analysis
*Build Your Own Panel Eligible [?]
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$584
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Description:
Fanconi's Anemia is an autosomal recessive disease that causes patients to suffer bone marrow failure, congenital malformations, chromosomal instability, and increased risk of cancer. Approximately 1 in 87 individuals of Ashkenazi Jewish heritage are carriers. In this population, a single DNA mutation accounts for approximately 83%.
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Price:
$584
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Fatty Acid Panel, Comprehensive (C8-C26), Serum
*Build Your Own Panel Eligible [?]
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$962
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Description:
- Checks levels of fatty acids.
- Analyzes fat components in blood.
- Measures essential acid levels.
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Price:
$962
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Fatty Acid Panel, Essential (C12-C22), Serum
*Build Your Own Panel Eligible [?]
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$672
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Description:
- Analyzes essential fatty acid levels
- Supports cardiovascular and brain health
- Helps assess dietary fat intake:
Patient Instructions:
Patient should fast for 9-12 hours prior to collection of the specimen. Patient should not consume alcohol for 24 hours prior to collection of the specimen.
Categories:
Price:
$672
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Fatty Acid Panel, Essential (C12-C22), Serum
*Build Your Own Panel Eligible [?]
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$672
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Description:
- Analyzes essential fatty acid levels
- Supports cardiovascular and brain health
- Helps assess dietary fat intake:
Patient Instructions:
Patient should fast for 9-12 hours prior to collection of the specimen. Patient should not consume alcohol for 24 hours prior to collection of the specimen.
Categories:
Price:
$672
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Fatty Acid Panel, Mitochondrial (C8-C18), Serum
*Build Your Own Panel Eligible [?]
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$439
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Description:
Mitochondrial Fatty Acids (C8-C18), to be used to evaluate patients for certain mitochondrial fatty acid oxidation defects as well as for monitoring of dietary therapy.
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Price:
$439
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Feather Mix IgE (Chicken, Duck, Goose, Turkey)
*Build Your Own Panel Eligible [?]
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$249
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Description:
- Detect feather allergy trigger sources
- Screen for bird-related breathing issues
- Identify bedding causing skin rashes
Categories:
Price:
$249
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Febrile Antibodies Panel
*Build Your Own Panel Eligible [?]
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$730
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Description:
This panel comprises antibody testing for infections caused by Ricketssia rickettsii, Richetssia typhi, Salmonella, and Brucella in patients with fever. A 4-fold change in titers of antibodies between acute and convalescent sera confirms the infection. This panel provides targeted identification of antibodies, which supports differential diagnosis and can provide evidence of exposure.R rickettsii causes Rocky Mountain spotted fever (RMSF), the most severe rickettsial disease in the United States. RMSF is transmitted via several species of ticks and occurs most commonly in North Carolina, Tennessee, Missouri, Arkansas, and Oklahoma. Fever and headache along with other nonspecific symptoms begin 3 to 12 days after the bite. Serious complications that affect multiple systems may develop quickly and can lead to death in days, especially in children under 10 years old. Thus, early diagnosis and treatment are critical to survival [1].R typhi causes flea-borne (murine) typhus. The geographic distribution of murine typhus extends throughout tropical and subtropical areas worldwide; it is rare in the United States, occurring mainly in Southern California, Hawaii, and Texas. Fever begins with chills and can last about 12 days. Severe complications can happen, if the infection is not treated, but are unusual [2].Salmonella infection can be caused by eating contaminated foods including vegetables, eggs, chicken, pork, and fruits. It can also spread between people and from animals to people. Common symptoms, such as diarrhea, fever, and stomach cramps, are usually self-limiting. However, children under 5 years old, adults over 65, and people with compromised immune systems may develop serious or fatal complications [3]. This panel can detect antibodies to 5 Salmonella antigens: H type A, B, and D; O type Vi and D.Brucella infections are commonly acquired from farm animals and raw dairy products in countries without effective public health and domestic animal health programs. Fever and other nonspecific symptoms of brucellosis start suddenly and later may become remittent. Recurrent brucellosis affects multiple systems with endocarditis as one of the most severe complications [4].Clinical false-negative results for IgG- and IgM-based serologic tests can occur due to compromised immunity, testing before antibody response has started, or the presence of interfering substances in host serum. A 4-fold change in titers of antibodies between acute and convalescent sera confirms the infection [1,2,4].The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.References1. Rocky Mountain spotted fever (RMSF). Centers for Disease Control and Prevention. Accessed September 25, 2021. https://www.cdc.gov/rmsf/index.html2. Flea-borne (murine) typhus. Centers for Disease Control and Prevention. Accessed September 25, 2021. https://www.cdc.gov/typhus/murine/index.html3. Salmonella. Centers for Disease Control and Prevention. Accessed September 25, 2021. https://www.cdc.gov/salmonella/4. Brucellosis. Centers for Disease Control and Prevention. Accessed September 25, 2021. https://www.cdc.gov/brucellosis/
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Price:
$730
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Fecal Fat, Qualitative
*Build Your Own Panel Eligible [?]
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$160
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Description:
Results may indicate malabsorption or maldigestion. False positive results can occur due to mineral oil or castor oil present in the specimen. Large number of neutral fat globules may indicate steatorrhea.
Categories:
Price:
$160
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Fecal Fat, Total, Quantitative
*Build Your Own Panel Eligible [?]
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$398
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Description:
Increased in disease of the pancreas, cystic fibrosis, celiac syndrome, bile duct obstruction, diarrhea, and lipase deficiency.
Categories:
Price:
$398
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Fecal Globin by Immunochemistry (InSure®)
*Build Your Own Panel Eligible [?]
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$325
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Description:
- Detects hidden blood in stool.
- Screens for colorectal cancer early.
- Simple test for digestive health check.
Includes:
Fecal Globin by Immunochemistry (InSure®)
Patient Instructions:
Fecal specimens should be collected from toilet water and brushed on the. Please visit the Lab to get the InSure® FOBT test card needed for this test.
Keep the specimen at room temperature. Be sure to add the date and time of collection.
This test is not available for California, Missouri, or Pennsylvania residents.
Categories:
Price:
$325
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Fecal Globin by Immunochemistry (InSure®)
*Build Your Own Panel Eligible [?]
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$325
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Description:
- Detects hidden blood in stool
- Screens for early colon cancer signs
- Uses stool sample to find blood
Includes:
Fecal Globin by Immunochemistry (InSure®)
Patient Instructions:
You will need to go to Quest to pick up the InSure® FOBT test card.
See the collection instructions included in the InSure® test kit.
Categories:
Price:
$325
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Fecal Globin by Immunochemistry (InSure®)
*Build Your Own Panel Eligible [?]
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$243
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Description:
- Detects hidden blood in stool
- Screens for colon cancer signs
- Checks digestive tract health
Includes:
Fecal Globin by Immunochemistry (InSure®)
Categories:
Price:
$243
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Fecal Leukocyte Stain
*Build Your Own Panel Eligible [?]
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$130
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Description:
The presence of leukocytes is an indicator of inflammation. Generally, inflammation is a product of bacteria-host interaction.
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Price:
$130
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Feel Good Summer Package
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$353
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Description:
- Measure how well your body burns energy
- Balance your hormones for steady moods
- Assess your risk for weight changes
Includes:
Comprehensive Metabolic Profile (includes eGFR): Albumin, Albumin/Globulin Ratio (calculated), Alkaline Phosphatase, ALT, AST, BUN/Creatinine Ratio (calculated), Calcium, Carbon Dioxide, Chloride, Creatinine with GFR Estimated, Globulin (calculated), Glucose, Potassium, Sodium, Total Bilirubin, Total Protein, Urea Nitrogen
Tri-iodothyronine Free (FT3)
Thyroxine Free, Direct Dialysis (FT4)
Cortisol, AM
Insulin.
Complete Blood Count / CBC (includes Differential and Platelets):
WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet Count, MPV and Differential (Absolute and Percent - Neutrophils, Lymphocytes, Monocytes, Eosinophils, and Basophils)
Thyroid-Stimulating Hormone (TSH)
Leptin
Estimated turnaround for results is 4-8 business days.
Vitamin D, 25-OH, Total;
Vitamin D, 25-OH, D3;
Vitamin D, 25-OH, D2
Patient Instructions:
You should fast for 12 hours before collection of the specimen. Fasting is defined as no consumption of food or beverage other than water for at least 12 hours before testing. Specimens should be collected in the morning between 7 AM and 9 AM. Samples should not be collected during or soon after the administration of heparin. Assay is not recommended when patient is receiving prednisone/prednisolone therapy due to cross reactivity with the antibody used in this assay.
Estimated turnaround for results is 8 business days. If confirmation testing is required, the estimated time may be extended.
Categories:
Hormones & metabolism,
Price:
$353
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Felbamate
*Build Your Own Panel Eligible [?]
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$180
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Description:
Felbamate is an antiepileptic drug used to treat patients with a variety of types of seizures. Therapeutic drug monitoring is useful to optimize dose and avoid toxicity.
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Price:
$180
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Female Comprehensive Hormone Panel (LC/MS/MS)
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$454
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Description:
This test uses equilibrium dialysis methodology.
The Testosterone test in this panel will provide levels of Total Testosterone results ranging from 0 to 9,999. However, any value greater than 9,999 will be displayed as ">10,000" (over 10,000) instead of a specific number.
Significant deviations from the normal range may require further evaluation by your physician.
Includes:
Complete Blood Count / CBC (includes Differential and Platelets): WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet Count, MPV and Differential (Absolute and Percent - Neutrophils, Lymphocytes, Monocytes, Eosinophils, and Basophils)
Comprehensive Metabolic Profile ( includes eGFR ): Albumin, Albumin/Globulin Ratio (calculated), Alkaline Phosphatase, ALT, AST, BUN/Creatinine Ratio (calculated), Calcium, Carbon Dioxide, Chloride, Creatinine with GFR Estimated, Globulin (calculated), Glucose, Potassium, Sodium, Total Bilirubin, Total Protein, Urea Nitrogen
Dehydroepiandrosterone (DHEA-s) Sulfate
Estradiol
Estrogens (Total), Serum
Lipid Panel:Cholesterol, total; high-density lipoprotein (HDL) cholesterol; low-density lipoprotein (LDL) cholesterol (calculated); triglycerides; Non-HDL Cholesterol (calculated).
Pregnenolone, LC/MS
Progesterone
Testosterone, Free and Total, LC/MS/MS
Thyroid-Stimulating Hormone (TSH)
Tri-iodothyronine Free (FT3)
This testosterone test will also provide Total Testosterone results when the value is >1500 but <10,000.
Patient Instructions:
Patient should fast for 12-14 hours prior to collection of the specimen. If using a testosterone cream please be sure you have not rubbed any into the antecubital area of your arm for the last 24 hours as it can give elevated results. No radioisotopes administered 24 hours prior to venipuncture. Some tests in this panel may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H or coenzyme R). Patient should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.
Estimated turnaround for results is 7 business days. If confirmation testing is required, the estimated time may be extended.
Categories:
Hormones & metabolism,
Specific blood tests for women,
Price:
$454
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Female Hormone Optimization Panel (LC/MS/MS)
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$502
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Description:
This test uses equilibrium dialysis methodology.
The Testosterone test in this panel will provide levels of Total Testosterone results ranging from 0 to 9,999. However, any value greater than 9,999 will be displayed as ">10,000" (over 10,000) instead of a specific number.
Significant deviations from the normal range may require further evaluation by your physician.
Includes:
Complete Blood Count / CBC (includes Differential and Platelets): WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet Count, MPV and Differential (Absolute and Percent - Neutrophils, Lymphocytes, Monocytes, Eosinophils, and Basophils)
Comprehensive Metabolic Profile ( includes eGFR ): Albumin, Albumin/Globulin Ratio (calculated), Alkaline Phosphatase, ALT, AST, BUN/Creatinine Ratio (calculated), Calcium, Carbon Dioxide, Chloride, Creatinine with GFR Estimated, Globulin (calculated), Glucose, Potassium, Sodium, Total Bilirubin, Total Protein, Urea Nitrogen
Cortisol, Total
Dehydroepiandrosterone (DHEA-s) Sulfate
DHEA (Dehydroepiandrosterone), Unconjugated, LC/MS/MS
Estradiol
Follicle-stimulating Hormone (FSH)
Luteinizing Hormone (LH)
Hemoglobin (Hgb) A1c
Insulin-Like Growth Factor I (IGF-I, LC/MS)
Lipid Panel:Cholesterol, total; high-density lipoprotein (HDL) cholesterol; low-density lipoprotein (LDL) cholesterol (calculated); triglycerides; Non-HDL Cholesterol (calculated).
Pregnancy test (very early) - Human Chorionic Gonadotropin (hCG), Total, Quantitative
Sex Hormone binding Globulin, (SHBG)
Testosterone, Free and Total, LC/MS/MS
Thyroid-Stimulating Hormone (TSH)
Thyroxine Free (FT4), Immunoassay
Tri-iodothyronine Free (FT3)
Vitamin D, 25-Hydroxy LC/MS/MS: Vitamin D, 25-OH, Total; Vitamin D, 25-OH, D3; Vitamin D, 25-OH, D2
This testosterone test will also provide Total Testosterone results when the value is >1500 but <10,000.
Patient Instructions:
Patient should fast for 12-14 hours prior to collection of the specimen. Fasting is defined as no consumption of food or beverage other than water before testing. Cortisol, Total assay not recommended when patient is on prednisone/prednisolone therapy due to cross reactivity with the antibody used in this assay. If using a testosterone cream please be sure you have not rubbed any into the antecubital area of your arm for the last 24 hours as it can give elevated results. Some tests in this panel may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H or coenzyme R). Patient should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.
Estimated turnaround for results is 7 business days. If confirmation testing is required, the estimated time may be extended.
Categories:
Hormones & metabolism,
Specific blood tests for women,
Price:
$502
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Fentanyl and Norfentanyl
*Build Your Own Panel Eligible [?]
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$326
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Description:
Fentanyls are extensively used for anesthesia and analgesia. There are fentanyl transdermal patches available that are used in chronic pain management.
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Price:
$326
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Ferret Epithelium (e217) IgE
*Build Your Own Panel Eligible [?]
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$49
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Description:
This allergen-specific IgE antibody test quantifies an individual’s IgE response to ferret epithelium. It is an in vitro quantitative assay that is intended to be used in conjunction with other clinical information to aid in the diagnosis of allergic diseases [1]. While allergen-specific serum IgE testing is considered comparable to skin testing in many instances, both the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology recognize that allergen-specific serum IgE testing may be preferred in some clinical situations. These include 1) the presence of widespread skin disease, 2) the recent use of antihistamines or other medications that can affect the results of allergy skin tests, 3) uncooperative patients, and 4) medical history suggesting that allergen skin testing would pose a significant risk for a serious allergic reaction [1]. A definitive clinical diagnosis of allergy should not be based on the results of any single diagnostic method, but should be made by a trained healthcare provider after all clinical and laboratory findings have been evaluated. More specific information about this allergen can be found at http://www.phadia.com/en/products/allergy-testing-products/immunocap-allergen-information/epidermals-and-animal-proteins/allergens/ferret-epithelium/ Reference 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(Suppl 3):S1-S148.
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Price:
$49
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